27 research outputs found
Chaos and Logistic Map based Key Generation Technique for AES-driven IoT Security
Several efforts have been seen claiming the lightweight block ciphers as a necessarily suitable substitute in securing the Internet of Things. Currently, it has been able to envisage as a pervasive frame of reference almost all across the privacy preserving of smart and sensor-oriented appliances. Different approaches are likely to be inefficient, bringing desired degree of security considering the easiness and surely the process of simplicity but security. Strengthening the well-known symmetric key and block dependent algorithm using either chaos motivated logistic map or elliptic curve has shown a far-reaching potential to be a discretion in secure real-time communication. The popular feature of logistic maps, such as the un-foreseeability and randomness often expected to be used in dynamic key-propagation in sync with chaos and scheduling technique towards data integrity. As a bit alternation in keys, able to come up with oversize deviation, also would have consequence to leverage data confidentiality. Henceforth it may have proximity to time consumption, which may lead to a challenge to make sure instant data exchange between participating node entities. In consideration of delay latency required to both secure encryption and decryption, the proposed approach suggests a modification on the key-origination matrix along with S-box. It has plausibly been taken us to this point that the time required proportionate to the plain-text sent while the plain-text disproportionate to the probability happening a letter on the message made. In line with that the effort so far sought how apparent chaos escalates the desired key-initiation before message transmission
Association of serum pregnancy associated plasma protein: a with gestational diabetes mellitus
Background: Gestational diabetes mellitus is defined as diabetes diagnosed during pregnancy that is not clearly overt diabetes. GDM has many adverse consequences on the health of mother and fetus.
Methods: This cohort study was carried out involving 77 women of 11 to14-week pregnant attending in the Gynecology & Obstetrics and Fetomaternal Medicine OPD, BSMMU from September 2020 to August 2021.
Results: Respondents were divided into two groups. Low PAPP-A group (<0.5MoM) and normal PAPP-A group (>0.5MoM). In low PAPP-A group, out of 16 respondents, 8 (42.1%) developed GDM and remaining 8(13.8%) were euglycemic. Whereas, in normal PAPP-A group, out of 61 respondents, majority 50 (86.2%) were euglycemic and only 11 (57.9%) women developed GDM. A total 19 (24.68%) respondents developed GDM from both low and normal PAPP-A group. ROC analysis of PAPP-A level for detection of GDM, a AUC value of 0.889 (95% CI 0.818-0.960) found which was statistically significant. A cut off value of ≤16.80 showed the highest Youden index (0.652) with 89.4% sensitivity and 81% specificity, the accuracy was 83.35. Moreover, a cut off value ≤16.80 showed PPV and NPV of 62.1% and 95.9%, respectively. PAPP-A level of GDM detected (10.32±5.56) µg/ml was significantly lower from non GDM mothers (25.08 ±9.85) µg/ml, where p<0. 001.
Conclusions: Study finding revealed that maternal serum PAPP-A level was lower in 11-14 weeks of pregnancy who subsequently developed GDM. So, a low PAPP-A level (<0.5 MoM) in 11-14 weeks of pregnancy is associated for development of GDM
ANTIOXIDATIVE POTENTIAL OF DURANTA REPENS (LINN.) FRUITS AGAINST H2O2 INDUCED CELL DEATH IN VITRO
The effects of Duranta repens fruits were investigated on H2O2 induced oxidative cell death to evaluate its antioxidative potential in vitro. HEK293T cells were treated with different concentrations [0-1000 µg/ ml] of ethanol extract (E-Ex) and methanol extract (M-Ex) of D. repens for 24h, and then treated with 100 µM H2O2 for 24h. Cell viability, antioxidant parameters of cells, and antioxidant constituents of the extracts were determined. Treatment with limited dose of E-Ex or M-Ex increased the survival rate of H2O2–treated HEK293T cells, however the extra-high dose showed growth inhibitory effect. Treatment with E-Ex or M-Ex protected cellular lipid per-oxidation. In vitro analyses showed the 2,2-diphenyl-1-picrylhydrazyl and H2O2 scavenging activities as well as reducing potential of the extracts. We report here that the limited dose of E-Ex and M-Ex possess antioxidative potential, which can protect H2O2-induced oxidative cell damage
Prevalence and seroprevalence of Plasmodium infection in Myanmar reveals highly heterogeneous transmission and a large hidden reservoir of infection.
Malaria incidence in Myanmar has significantly reduced over recent years, however, completeness and timeliness of incidence data remain a challenge. The first ever nationwide malaria infection and seroprevalence survey was conducted in Myanmar in 2015 to better understand malaria epidemiology and highlight gaps in Annual Parasite Index (API) data. The survey was a cross-sectional two-stage stratified cluster-randomised household survey conducted from July-October 2015. Blood samples were collected from household members for ultra-sensitive PCR and serology testing for P. falciparum and P. vivax. Data was gathered on demography and a priori risk factors of participants. Data was analysed nationally and within each of four domains defined by API data. Prevalence and seroprevalence of malaria were 0.74% and 16.01% nationwide, respectively. Prevalent infection was primarily asymptomatic P. vivax, while P. falciparum was predominant in serology. There was large heterogeneity between villages and by domain. At the township level, API showed moderate correlation with P. falciparum seroprevalence. Risk factors for infection included socioeconomic status, domain, and household ownership of nets. Three K13 P. falciparum mutants were found in highly prevalent villages. There results highlight high heterogeneity of both P. falciparum and P. vivax transmission between villages, accentuated by a large hidden reservoir of asymptomatic P. vivax infection not captured by incidence data, and representing challenges for malaria elimination. Village-level surveillance and stratification to guide interventions to suit local context and targeting of transmission foci with evidence of drug resistance would aid elimination efforts
Immunohepatotoxicity of the persistent environmental pollutants perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS)
Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS), manufactured for a variety of industrial and consumer applications, are ubiquitous environmental pollutants. Their accumulation in humans and wildlife raises serious health concerns. Here, we examined the potential effects of PFOA and PFOS on the innate immune system in mice. Short-term dietary exposure to high doses reduces the total number and subpopulations of circulating white blood cells. Moreover, production of proinflammatory cytokines by macrophages in the peritoneal cavity and bone marrow, but not in the spleen following exposure to in vitro or in vivo stimulation by bacterial lipopolysaccharides is enhanced. With respect to adaptive immunity, PFOS reduces the total numbers of thymocytes and splenocytes and subpopulations thereof in a dose dependent fashion. Furthermore, comparison of wild-type mice and the corresponding knock-out strain lacking peroxisome proliferator-activated receptor-alpha revealed that these immunological changes are partially dependent on this receptor. Our further studies also show that sub-chronic dietary exposure to an environmentally relevant dose of PFOS does not alter the cellularity of the thymus and spleen and exerts no influence on humoral immune responses. To facilitate examination of the effects of PFOA and PFOS on the hepatic immune system, we developed a procedure for mechanical disruption that yields a larger number of functionally competent immune cells from this organ. In our last study, lower doses of PFOA or PFOS induced hypertrophy of hepatocytes and altered the hepatic immune status. Thus, we find that short-term, high- and low-dose exposure of mice to these fluorochemicals is immunohepatotoxic.Perfluorooktanat (PFOA) och perfluorooktansulfonat (PFOS) som tillverkas för många olika industri och konsumentprodukter, är globalt förekommande miljögifter. Deras ackumulering i människor och djur ger upphov till en stark oro för hälsoproblem. Vi har granskat effekterna av PFOA och PFOS på det medfödda, ospecifika immunförsvaret. Exponering för höga doser via maten under kort tid minskar det totala antalet cirkulerande vita blodkroppar samt delpopulationerna.. Immunsvaret ökar dock efter stimulering med bakteriella lipopolysaccharider både in vitro och in vivo , dvs produktionen av proinflammatoriska cytokiner av makrofager i bukhålan och benmärgen, men inte i mjälten ökar.. När det gäller adaptiv, specifik immunitet minskar PFOS det totala antalet tymocyter och splenocyter och deras olika subpopulationer. Vid exponering för lägre doser av PFOS induceras hepatomegali utan att påverka tymus eller mjälten. Vi kunde visa att peroxisomal proliferator-aktiverad receptor-alfa medierar effekterna utav PFOS i tymus samt delar av effekterna av PFOS i mjälten genom att använda möss som saknade denna receptor. . Dettastöds av vår studie med subkronisk exponering för en miljömässig dos av PFOS vilken inte ändrade den cellulära sammansättningen i vare sig tymus eller mjälte och inte hade något inflytande på det humorala immunsvaret. För att underlätta studier av hur PFOA och PFOS påverkar immunsystemet i levern utvecklade vi en metod för framrening av immunceller via mekanisk sönderdelning av levern, vilket gavett större antal av funktionella immunceller från detta organ. I vår sista studie kunde vi påvisa att lägre doser av PFOA eller PFOS inducerade hypertrofi av hepatocyter samt en påverkan av leverns immunförsvar
Evolution de l'épidémie du VIH/SIDA au Cambodge et élaboration d'un projet de notification de partenaires
Le Cambodge a été très touché par l'épidémie du VIH surtout depuis les années 90. Cependant le gouvernement cambodgien a montré une volonté exemplaire pour lutter contre cette épidémie en atteignant l'objectif du millénaire pour le développement 6 en 2010, l'objectif 6 étant "Combattre le VIH/sida, le paludisme et d'autres maladies". Cependant le Cambodge a une nouvelle ambition: celle d'attendre 0 nouvelle infection au VIH. L'objectif de ce travail a donc été l'élaboration d'une des stratégies qui pourrait permettre d'atteindre le 0 nouvelle infection. Cette stratégie est la notification de partenaires des personnes les plus à risque d'infection au VIH. Une revue et une analyse bibliographique a été entreprise afin d'identifier les stratégies déjà existantes dans d'autres PED. Onze articles répondant aux critères d'inclusions ont été analysés. Les résultats de cette analyse ont montré qu'aucun PED n'a encore mis en place une stratégie de notification de partenaires. Donc une revue bibliographique dans les pays développés, des entretiens avec des experts et des entretiens avec les populations cibles ont été nécessaires pour proposer une stratégie adaptée au contexte cambodgien. Donc une stratégie innovante basée sur les pays développés adaptée au contexte cambodgien a été proposée. La stratégie proposée pour le Cambodge comporte donc quatre méthodes au lieu de trois qui devraient être mises en place dans les mois à suivre. De plus une motivation financière pourrait être incluse pour que les partenaires viennent se faire dépister contre une somme d'argent définieLYON1-BU Santé (693882101) / SudocSudocFranceF
Chaos and Logistic Map Based Key Generation Technique for AES-Driven IoT Security
Several efforts has been seen claiming the lightweight block ciphers as a necessarily suitable substitute in securing the Internet of Things. Currently, it has been able to envisage as a pervasive frame of reference almost all across the privacy preserving of smart and sensor oriented appliances. Different approaches are likely to be inefficient, bringing desired degree of security considering the easiness and surely the process of simplicity but security. Strengthening the well-known symmetric key and block dependent algorithm using either chaos motivated logistic map or elliptic curve has shown a far reaching potentials to be a discretion in secure real-time communication. The popular feature of logistic maps, such as the un-foreseeability and randomness often expected to be used in dynamic key-propagation in sync with chaos and scheduling technique towards data integrity. As a bit alternation in keys, able to come up with oversize deviation, also would have consequence to leverage data confidentiality. Henceforth it may have proximity to time consumption, which may lead to a challenge to make sure instant data exchange between participating node entities. In consideration of delay latency required to both secure encryption and decryption, the proposed approach suggests a modification on the key-origination matrix along with S-box. It has plausibly been taken us to this point that the time required proportionate to the plain-text sent while the plain-text disproportionate to the probability happening a letter on the message made. In line with that the effort so far sought how apparent chaos escalates the desired key-initiation before message transmission.</p
Effects of Plasma transfusion on various hematological and biochemical parameters in goats
This study investigated the clinical and hematological responses of plasma transfusion and hematinic administration in severely anemic goats. The blood profile of the recipient goats were assessed for hematological: Total Erythrocyte Count (TEC), Total Leukocyte Count (TLC), Hemoglobin (Hb), Packed Cell Volume (PCV), Neutrophil, Eosinophil, Lymphocyte, Monocyte, and Electrolytes and Biochemical parameters: Alanine Transaminase (ALT), Aspartate Transaminase (AST), Creatinine and Total Protein (TP) before and after (1st, 7th, 14th, 21th, 28th days) treatment with plasma transfusion or hematinic administration. In plasma transfusion group (Group A), TEC, PCV, Hb, ALT, AST and TP were increased significantly (p < 0.01) at 1st, 7th, 14th, 21th, 28th days of post-transfusion in comparison to pre-transfusion values. In the hematinic group (Group B), two patients died treated with hematinic. However, no significant changes (p > 0.05) in clinical parameters, electrolytes (K+, Na+ and Cl−) levels and creatinine values were observed in recipient goats after plasma transfusion and hematinic administration. After 28 days of treatment, all patients of plasma transfusion group (100%) and three in hematinic treatment group (60%) were recovered successfully. The plasma transfusion was found superior to hematinic administration to upgrade the hematological and biochemical parameters in anemic goats. It did not produce any adverse reaction in the recipient goats. Plasma transfusion could be an effective tool for the clinical management of anemic goats. [J Bangladesh Agril Univ 2023; 21(1.000): 38-45
Chaos and Logistic Map Based Key Generation Technique for AES-Driven IoT Security
Several efforts has been seen claiming the lightweight block ciphers as a necessarily suitable substitute in securing the Internet of Things. Currently, it has been able to envisage as a pervasive frame of reference almost all across the privacy preserving of smart and sensor oriented appliances. Different approaches are likely to be inefficient, bringing desired degree of security considering the easiness and surely the process of simplicity but security. Strengthening the well-known symmetric key and block dependent algorithm using either chaos motivated logistic map or elliptic curve has shown a far reaching potentials to be a discretion in secure real-time communication. The popular feature of logistic maps, such as the un-foreseeability and randomness often expected to be used in dynamic key-propagation in sync with chaos and scheduling technique towards data integrity. As a bit alternation in keys, able to come up with oversize deviation, also would have consequence to leverage data confidentiality. Henceforth it may have proximity to time consumption, which may lead to a challenge to make sure instant data exchange between participating node entities. In consideration of delay latency required to both secure encryption and decryption, the proposed approach suggests a modification on the key-origination matrix along with S-box. It has plausibly been taken us to this point that the time required proportionate to the plain-text sent while the plain-text disproportionate to the probability happening a letter on the message made. In line with that the effort so far sought how apparent chaos escalates the desired key-initiation before message transmission.</p