Physico-chemical basis of the durum wheat milling quality

Physico-chemical basis of the [i]durum wheat[/i] milling quality. ICC Conference in association with AGS

In-Depth Study of Durum Wheat Grain Tissue Distribution at Milling

The starchy endosperm proportion in durum wheat grain and its ability to be isolated from the peripheral tissues appear as main intrinsic characteristics potentially related to the milling value but still difficult to assess. In this study, several durum wheat samples displaying distinct grading characteristics were analyzed and processed through a pilot mill. The histological composition of grains and milling fractions was monitored by using identified biochemical markers of each wheat grain tissue. Contrasted milling yields of semolina and flour were observed between samples, despite displaying a similar starchy endosperm proportion determined by hand dissection. These yields were related both to differences in the starchy endosperm extraction and to the presence of the aleurone layer, particularly its cellular content. Furthermore, two distinct types of fractionation behavior of the aleurone layer were distinguished depending on the wheat grain sample. Extraction of the envelopes and embryonic axis into semolina and flours were found negligible in comparison with the other tissues

Identification of key factors influencing endosperm extraction in durum wheat

Identification of key factors influencing endosperm extraction in durum wheat. Journée de l’école doctorale Sciences des Procédés-Science des aliment

Compréhension et détermination des facteurs clés de la valeur semoulière

La valeur semoulière d’un lot de blé dur rend compte de son potentiel de rendement en semoule et de la pureté de ses produits. Elle dépend d’un grand nombre de facteurs qui déterminent le comportement des blés durs en mouture. La compréhension des mécanismes sous-jacents offre des perspectives pour sa maîtrise et son optimisation. Au-delà de l’identification des facteurs influents, le développement de méthodes de mesure des caractéristiques des grains en vue de déterminer leur valeur semoulière demeure un enjeu majeur pour les industries de première transformation. Cet article décrit l’état des connaissances sur la valeur semoulière, ainsi que l’évolution des méthodes de mesure permettant de l’apprécier

Synthesis of 6-[¹8F]fluoro-PBR28, a novel radiotracer for imaging the TSPO 18 kDa with PET

6-Fluoro-PBR28 (N-(6-fluoro-4-phenoxypyridin-3-yl)-N-(2-methoxybenzyl)acetamide), a fluorinated analogue of the recently developed TSPO 18 kDa ligand PBR28, was synthesized and labelled with fluorine-18. 6-Fluoro-PBR28 and its 6-chloro/6-bromo counterparts were synthesized in six chemical steps and obtained in 16%, 10% and 19% overall yields, respectively. Labelling with fluorine-18 was performed in one single step (chlorine/bromine-for-fluorine heteroaromatic substitution) using a Zymate-XP robotic system affording HPLC-purified, ready-to-inject, 6-[(18)F]fluoro-PBR28 (>95% radiochemically pure). Non-decay-corrected overall yields were 9-10% and specific radioactivities ranged from 74 to 148 GBq/μmol. In vitro binding experiments, dynamic μPET studies performed in a rat model of acute neuroinflammation (unilaterally, AMPA-induced, striatum-lesioned rats) and ex vivo autoradiography on the same model demonstrated the potential of 6-[(18)F]fluoro-PBR28 to image the TSPO 18 kDa using PET