Faktori rizika promena stanja usta i zuba dece obolele od epilepsije - informativni rad

Epilepsy is the most common neurological disorder in people of all ages. Based on the data regarding the prevalence of epilepsy in other countries, about 12,000 individuals under the age of 18 are estimated to suffer from active epilepsy. Children with epilepsy are a high risk group for oral diseases primarily due to psychiatric and psycho-social consequences of the primary disorder as well as the adverse effects of anti-epileptic therapy. Due to the primary disorder, children with epilepsy have reduced motivation for a number of activities, reduced mental and physical abilities, neglected social contacts, more difficult adoption of knowledge, skills, positive attitudes and behavior as well as general and oral healthcare. In children with epilepsy, there is an additional risk for oral diseases due to the adverse effects of anti-epileptic therapy such as gingival hyperplasia. Studies in other countries and in Serbia showed higher prevalence and frequency of oral diseases compared to the control group of healthy children of the same age. This paper emphasizes the need for dental educational work with children with epilepsy and their parents as well as doctors who treat the primary disorder.Epilepsija je najčešći neurološki poremećaj koji pogađa ljude svih uzrasta. Na osnovu podataka o prevalenciji epilepsije u drugim zemljama, procenjuje se da u Srbiji oko 12.000 dece i omladine mlađe od 18 godina boluje od aktivne epilepsije. Deca obolela od epilepsije predstavljaju grupu visokog rizika za oralna oboljenja, pre svega zbog psihijatrijskih i psihosocijalnih posledica osnovne bolesti, ali i zbog neželjenih dejstava antiepileptične terapije. Zbog osnovne bolesti, kod dece s epilepsijom smanjena je motivacija za bavljenjem mnogim aktivnostima, smanjuju im se mentalne i fizičke sposobnosti, zanemaruju socijalni kontakti, otežano im je usvajanje znanja i veština, pozitivnih stavova i ponašanja, a time i briga za sopstveno opšte i oralno zdravlje. Kod dece s epilepsijom postoji i dodatni rizik od razvoja oralnih oboljenja zbog neželjenog dejstva antiepileptične terapije, koja loše utiče na stanje usta i zuba, najčešće u vidu hiperplazije gingive. Istraživanja u svetu i kod nas pokazala su da među ovom decom postoji veća rasprostranjenost i učestalost oralnih oboljenja nego kod zdrave dece istog uzrasta. Istaknuta je potreba za ciljnim stomatološkim zdravstvenovaspitnim radom sa decom obolelom od epilepsije i njihovim roditeljima, kao i s lekarima koji leče osnovno oboljenje

Importance of cultivar and harvest date on the yield and processing quality of sugar beet

The results assessed from sugar beet microtrials at Kljajićevo (Serbia) in 2010 harvested at three harvest periods demonstrated that the average root yield tended to increase from the first to the third harvest period. The average increase in root yield between the first and the second harvest period was 29.06 t ha-1 or 32.76%, between the second and the third period 14.77 t ha-1 or 12.54% and between the first and the third period 43.83 t ha-1 or 49.40%. In average, the content of sugar in root showed a similar tendency. The highest increase in this parameter was registered between the second and the third harvest period and it amounted to 1.00% abs. Other indicators of sugar beet processing quality showed a slow increase or slight decrease depending on the harvest date, probably due to plentiful rainfall in September. Mean granulated sugar yield had an increasing tendency: 3.413 t ha-1 or 32.82% between the first and the second harvest period, 2.820 t ha-1 or 20.42% between the second and the third and 6.233 t ha-1 or 59.94% between the first and the third period

Epilepsy and interictal epileptiform activity in patients with autism spectrum disorders

Purpose: The purpose of this study was to determine the prevalence of epilepsy and subclinical epileptiform abnormalities in children with autism spectrum disorder (ASD), and to investigate its effects on core autistic symptoms and adaptive behavior skills. Methods: Patients with diagnosis of ASD who met full criteria on Autism Diagnostic Interview-Revised (ADI-R) were included in the study. Adaptive behavior skills were assessed by Vineland Adaptive Behavior Scale-II (VABS-II). Clinical assessment for epilepsy and video electroencephalography (EEG) (v-EEG) examinations during wakefulness and/or sleep were prospectively performed in all patients. Results: A total of 112 patients with diagnosis of ASD of mean age 6.58 +/- 3.72 were included in the study. Based on clinical and v-EEG assessments, three groups of patients were defined: 1) patients with epilepsy (n = 17; 15.2%); 2) patients with epileptiform discharges in absence of clinical seizures (n = 14; 12.5%); 3) patients without epilepsy and without epileptiform discharges ( n = 81; 72.3%). There were no significant differences between three groups of patients on ADI-R subscores. Speech development was also not significantly related to epilepsy. There was a slight tendency of the VABS-II motor skills score to be higher in the group of patients with autism without clinical diagnosis of epilepsy and without subclinical epileptiform discharges (p lt 0.05) in comparison with the two other groups. According to this tendency, we might claim that patients with higher scores on motor skills could have 0.88 times lower odds for having epileptiform EEG activity. Conclusions: According to our results, we were not able to detect differences in the ADI-R between the three populations with ASD, all with unknown etiology. Epilepsy, as well as subdinical epileptic discharges, showed small effects on Motor Skills in patients with autism, and had no effect on adaptive behavior Communication/Socialization/Daily Living Skills