Clinical perspective on non-suicidal self injury in adolescents : a qualitative study

There has been an increase in the number of adolescents who engage in non-suicidal selfinjury (NSSI). This qualitative study explored clinical social workers’ perceptions of the causes of NSSI and the processes whereby social workers develop treatment for this behavior. This research was based on 10 in-person interviews conducted with Massachusetts licensed clinical social workers (mean average experience=20 years) who treat adolescent self-harm. Findings suggest adolescents often feel pressure to cut in order to fit in and therefore are more likely to engage in self-harm if their peers are encouraging this behavior. Further findings suggest that many participants seemed less aware than the literature implied about how neuroscience and attachment theory can be utilized to explain self-harming behavior. In order to develop effective treatment methods, it is imperative that clinicians increase their understanding of the motivations for NSSI, especially the influence of peer relationships. At the graduate level, social work students should learn how to apply theoretical frameworks to guide their interventions and clinical practice. The results of this study expand knowledge of NSSI in adolescents as well as how to best educate emerging social workers about effective treatment methods

Procedural Discretionary Decisions and Access to Justice Before Administrative Tribunals

This thesis considers procedural discretionary decision-making by administrative tribunals and access to justice for marginalized and low-income individuals. I begin by reviewing literature regarding discretionary decision-making, access to justice, procedural justice, and ideal theories focusing on transparent and respectful engagement and dialogue between decision-makers and litigants. I then analyze three case studies regarding procedural discretionary decision-making and accommodations in the hearing process, addressing primarily disability and language barriers experienced by litigants before the Social Benefits Tribunal, Human Rights Tribunal of Ontario, and Landlord and Tenant Board. I then compare theories of discretionary decision-making with actual decision-making practices employed by tribunal adjudicators. While certain positive practices may play a role in achieving more meaningful engagement between decision-makers and parties, my analysis also reveals systemic barriers to access to justice and limitations of procedural discretionary decision-making by tribunals

Age Differences In Social Support And Mental Health In Male Veterans

Psychological concerns among United States veterans of all ages are considerable, however social support may help improve the mental health of these individuals. The protective effect of social support on mental health has been observed in older and younger samples of veterans, but it is unclear whether social support may be more beneficial at certain life stages. By assessing cross-sectional survey data from a large sample of veterans using an extreme groups approach (EGA), the impact of perceived support, structural support, and community integration on mental health difficulty and screening positive for a mental disorder was assessed. The effect of individual perceived social support items on mental health was also evaluated. Given evidence from the socio-emotional selectivity theory that older individuals place greater importance on close supportive relationships relative to younger individuals, we hypothesized that older veterans would benefit most from social support, especially from emotional-based types of support. There were significant interactions for age and support, with higher perceived support significantly reducing mental health difficulty and likelihood of screening positive for a mental disorder in the younger but not older group, while community integration decreased mental health difficulty in the older but not younger group. The positive social interaction item predicted lower mental health difficulty in the younger group, while the emotional/affectionate support predicted lower mental health difficulty in the older group. Although the results showed mixed support for the socio-emotional selectivity theory, identifying these differences in benefit from social support can help improve care for veteran populations throughout the life course

From Idea to Paradigm: The Integrated Primary and Mental Health Care Model in North Carolina

The Affordable Care Act included funding for the piloting of the integration of mental health and physical health, a model that may help address poor outcomes and low quality of care for persons with mental illness. There is growing interest in this model and evidence for its effectiveness. This paper explores the development of the integration of physical and mental health care from an idea to a paradigm and explores how a model that has gained national attention can be implemented and spread at a local level. Using frameworks such as Kingdon's three streams model and the Advocacy Coalition Framework, as well as diffusion of innovation theory, in this study I look at the role that advocates, evidence, values, and policy played in the spread of the integrated health care model. This research triangulates three methods: a careful review of the literature, a systematic review of government policy documents, and in-depth policy interviews with key stakeholders and other experts in the field. I used non-probability and convenience sampling to identify potential participants based on positions of leadership and expertise related to integrated health care in North Carolina. I coded interviews and analyzed them for common themes. I interviewed six participants who represented elected government, bureaucratic government, academia, and advocacy. In the view of the participants, the spread of integrated care is driven by recognition of a problem, the view that integrated care is an attractive solution, and the excitement and collaboration of stakeholders. Participants also agreed that the integrated care model will be important in the future, becoming a permanent fixture in the way that primary care is practiced and the way persons with mental illness are treated. Their views, however, differed on the role of research, with half of the participants seeing research as not important in the spread of integrated care. Identified barriers to dissemination included payment models, cultural differences between providers, and a lack of clear definitions. Suggestions to overcome these barriers included creating a means for proponents to share lessons and clear definitions to facilitate communication.Master of Public Healt

The \u3cem\u3eHalo\u3c/em\u3e Effect: Willful Infringement and Enhanced Damages in Light of \u3cem\u3eHalo\u3c/em\u3e

The Supreme Court’s decision in Halo Electronics, Inc. v. Pulse Electronics, Inc. overruled the United States Court of Appeals for the Federal Circuit’s longstanding Seagate test and empowered district courts to exercise their discretion in deciding whether to enhance damages for willful patent infringement. In the three years since the Halo decision, district courts have developed their own approaches to addressing willfulness allegations at the various stages of litigation, including pleading, summary judgment, trial, and post-trial. This Article observes trends in how district courts have addressed willfulness claims at each stage of litigation, highlights factors courts have considered when declining to enhance damages for an infringer’s egregious misconduct, and identifies practice tips in view of the emerging trends in the case law

Discovery of a dark, massive, ALMA-only galaxy at z~5-6 in a tiny 3-millimeter survey

We report the serendipitous detection of two 3 mm continuum sources found in deep ALMA Band 3 observations to study intermediate redshift galaxies in the COSMOS field. One is near a foreground galaxy at 1.3", but is a previously unknown dust-obscured star-forming galaxy (DSFG) at probable $z_{CO}=3.329$, illustrating the risk of misidentifying shorter wavelength counterparts. The optical-to-mm spectral energy distribution (SED) favors a grey $\lambda^{-0.4}$ attenuation curve and results in significantly larger stellar mass and SFR compared to a Calzetti starburst law, suggesting caution when relating progenitors and descendants based on these quantities. The other source is missing from all previous optical/near-infrared/sub-mm/radio catalogs ("ALMA-only"), and remains undetected even in stacked ultradeep optical ($>29.6$ AB) and near-infrared ($>27.9$ AB) images. Using the ALMA position as a prior reveals faint $SNR\sim3$ measurements in stacked IRAC 3.6+4.5, ultradeep SCUBA2 850$\mu$m, and VLA 3GHz, indicating the source is real. The SED is robustly reproduced by a massive $M^*=10^{10.8}$M$_\odot$ and $M_{gas}=10^{11}$M$_\odot$, highly obscured $A_V\sim4$, star forming $SFR\sim300$ M$_{\odot}$yr$^{-1}$ galaxy at redshift $z=5.5\pm$1.1. The ultrasmall 8 arcmin$^{2}$ survey area implies a large yet uncertain contribution to the cosmic star formation rate density CSFRD(z=5) $\sim0.9\times10^{-2}$ M$_{\odot}$ yr$^{-1}$ Mpc$^{-3}$, comparable to all ultraviolet-selected galaxies combined. These results indicate the existence of a prominent population of DSFGs at $z>4$, below the typical detection limit of bright galaxies found in single-dish sub-mm surveys, but with larger space densities $\sim3 \times 10^{-5}$ Mpc$^{-3}$, higher duty cycles $50-100\%$, contributing more to the CSFRD, and potentially dominating the high-mass galaxy stellar mass function.Comment: Accepted for publication in ApJ. 2 galaxies, too many pages, 8 figures, 2 table

Policy Options for Financing Long-Term Care in the U.S.

Unlike many other developed nations, the U.S. has no system that protects its residents against the high costs of long-term care, which many people will need as they age. Medicaid coverage kicks in only after families have exhausted their resources. Until then, families bear the financial and caregiving burden of LTC themselves. In the absence of a national system, several states have considered or passed programs that offer some support for LTC. Many peer nations have more comprehensive systems to spread the risk for LTC costs across their population, through social insurance or other mechanisms. This Issue Brief reviews international models of financing LTC, as well as recent state efforts, to help U.S. policymakers design a program that can meet the LTC challenges of an aging population

Reversible Optogenetic Control of Subcellular Protein Localization in a Live Vertebrate Embryo.

We demonstrate the utility of the phytochrome system to rapidly and reversibly recruit proteins to specific subcellular regions within specific cells in a living vertebrate embryo. Light-induced heterodimerization using the phytochrome system has previously been used as a powerful tool to dissect signaling pathways for single cells in culture but has not previously been used to reversibly manipulate the precise subcellular location of proteins in multicellular organisms. Here we report the experimental conditions necessary to use this system to manipulate proteins in vivo. As proof of principle, we demonstrate that we can manipulate the localization of the apical polarity protein Pard3 with high temporal and spatial precision in both the neural tube and the embryo's enveloping layer epithelium. Our optimizations of optogenetic component expression and chromophore purification and delivery should significantly lower the barrier for establishing this powerful optogenetic system in other multicellular organisms

The effect of stress on the expression of the amyloid precursor protein in rat brain

AbstractThe abnormal processing of the amyloid precursor protein (APP) is a pivotal event in the development of the unique pathology that defines Alzheimer's disease (AD). Stress, and the associated increase in corticosteroids, appear to accelerate brain ageing and may increase vulnerability to Alzheimer's disease via altered APP processing. In this study, rats were repeatedly exposed to an unavoidable stressor, an open elevated platform. Previous studies in this laboratory have shown that a single exposure produces a marked increase in plasma corticosterone levels but animals develop tolerance to this effect between 10 and 20 daily sessions. Twenty-four hours after stress, there was an increase in the ratio of the deglycosylated form of APP in the particulate fraction of the brain, which subsequently habituated after 20 days. The levels of soluble APP (APPs) tended to be lower in the stress groups compared to controls except for a significant increase in the hippocampus after 20 days of platform exposure. Since APPs is reported to have neurotrophic properties, this increased release may represent a neuroprotective response to repeated stress. It is possible that the ability to mount this response decreases with age thus increasing the vulnerability to stress-induced AD-related pathology

Photometric Redshift Probability Distributions for Galaxies in the SDSS DR8

We present redshift probability distributions for galaxies in the SDSS DR8 imaging data. We used the nearest-neighbor weighting algorithm presented in Lima et al. 2008 and Cunha et al. 2009 to derive the ensemble redshift distribution N(z), and individual redshift probability distributions P(z) for galaxies with r < 21.8. As part of this technique, we calculated weights for a set of training galaxies with known redshifts such that their density distribution in five dimensional color-magnitude space was proportional to that of the photometry-only sample, producing a nearly fair sample in that space. We then estimated the ensemble N(z) of the photometric sample by constructing a weighted histogram of the training set redshifts. We derived P(z) s for individual objects using the same technique, but limiting to training set objects from the local color-magnitude space around each photometric object. Using the P(z) for each galaxy, rather than an ensemble N(z), can reduce the statistical error in measurements that depend on the redshifts of individual galaxies. The spectroscopic training sample is substantially larger than that used for the DR7 release, and the newly added PRIMUS catalog is now the most important training set used in this analysis by a wide margin. We expect the primary source of error in the N(z) reconstruction is sample variance: the training sets are drawn from relatively small volumes of space. Using simulations we estimated the uncertainty in N(z) at a given redshift is 10-15%. The uncertainty on calculations incorporating N(z) or P(z) depends on how they are used; we discuss the case of weak lensing measurements. The P(z) catalog is publicly available from the SDSS website.Comment: 29 pages, 9 figures, single colum