Awareness of Individual Daily Caloric Requirements and Food Energy Content and its Relation to Calorie Intake: A Multiple Baseline Design

The terms overweight and obesity are used to identify ranges of body weight that are linked to an increased risk for certain diseases and health problems such as cardiovascular disease, diabetes, sleep apnea, certain cancers, and others. Current estimates indicate that over two-thirds of American adults are overweight or obese while one-third of American children are overweight or obese. Therefore, this has become a significant public health issue. One strategy for combating overweight and obesity is to educate people about nutrition and the nutritional content of the food they consume. Nutrition labeling of prepackaged foods and calorie posting in restaurants are policies implemented to provide people with the needed information to make choices about food purchases. Through a multiple baseline design, this study analyzes the effects of caloric requirements knowledge and awareness of food energy content on calorie intake while self-monitoring in a college sample composed of Hispanic females

Atomic-Scale Interface Engineering of Majorana Edge Modes in a 2D Magnet-Superconductor Hybrid System

Topological superconductors are predicted to harbor exotic boundary states - Majorana zero-energy modes - whose non-Abelian braiding statistics present a new paradigm for the realization of topological quantum computing. Using low-temperature scanning tunneling spectroscopy (STS), we here report on the direct real-space visualization of chiral Majorana edge states in a monolayer topological superconductor, a prototypical magnet-superconductor hybrid system comprised of nano-scale Fe islands of monoatomic height on a Re(0001)-O(2$\times$1) surface. In particular, we demonstrate that interface engineering by an atomically thin oxide layer is crucial for driving the hybrid system into a topologically non-trivial state as confirmed by theoretical calculations of the topological invariant, the Chern number.Comment: 26 pages, 9 figure

Multi-Sensor Field Studies of Lightning and Implications for MTG-LI

Future geostationary satellite systems will offer a variety of improved observing capabilities which will be extremely useful for many applications like numerical weather forecasting, nowcasting of severe weather, climate research or hydrology. The planning for MTG (Meteosat Third Generation) includes an optical lightning imager (LI) as part of the payload. One requirement for a proper interpretation of these optical data is a better understanding of what components of a flash are to be seen from space and how these observations relate to ground based radio frequency observations. Therefore, the objectives of the present study concern the improvement of the understanding of the complex lightning process which then enables a proper interpretation of the optical data. For assessing the future performances and benefits of a geostationary lightning sensor this study takes advantage of the comprehensive lightning data sets obtained from the recent CHUVA field experiment performed in Brazil. (CHUVA - Cloud processes of tHe main precipitation systems in Brazil: A contribUtion to cloud resolVing modeling and to the GPM (GlobAl Precipitation Measurement)). During the rainy season of 2011-2012 a large number of ground based lightning detection systems was set up in the Sao Paulo area in Brazil. In the present study we look at the detailed radio frequency (RF) based observation from LINET (Lightning detection network operated by DLR, nowcast and USP) and observing strokes in the VLF/LF (very low and low frequency) range, the LMA (Lightning mapping array) from NASA observing RF sources in the VHF (very high frequency) range and the TRMM-LIS (Tropical Rainfall Measuring Mission-Lightning Imaging Sensor) optical space borne lightning imager. The LIS is used as a reference instrument for the future MTG-LI sensor as well as for the corresponding GLM sensor (Geostationary Lightning Mapper) on GOES-R. Thus it is possible to study the relations between the RF and optical signals from lightning in detail and to assess the performance of the future geostationary observations from a set of proxy satellite data generated from the ground based observations. In confirmation of previous studies, it was found that often a direct temporal coincidence of RF signals (LINET strokes) and optical pulses (LIS groups) exists. The short baseline configuration of LINET allowed to observe the strokes mapping the flash branches similar to LMA, but by locating the limited number of strong cloud strokes rather than a large number of weak source points from leader steps. An initial breakdown phase of vertically propagating sources can often be found in LINET and LMA data. The higher level LINET and LMA signals have higher probability to be optically detected. Lower level LINET and LMA signals are optically detected from above in case of missing high level precipitation as inferred from radar observations provided by USP. The new comprehensive data set allows for constructing proxy data for the future geostationary lightning mappers

Effectiveness of Feeding Therapy Approaches on Consumption and Dietary Variety in Children With Sensory-Based Feeding Challenges

This project was completed in collaboration with Hannah Michlmayer (OTR/L) at Therapy Services for Children in Seattle, Washington. The research team conducted a literature review to investigate the following question: For children ages 3-12 with sensory-based feeding challenges, what are the most effective interventions to improve dietary diversity and/or food acceptance? Evidence indicates that ABA-based interventions are the most studied, followed by video modeling and caregiver/parent training. These approaches demonstrate short-term increases in consumption and dietary variety. Most studies had small sample sizes with minimal long-term follow-up. There is a lack of research on group interventions, the SOS approach, and other sensory-based interventions (all used in OT practice). Further research in the following domains is strongly recommended: long-term follow-up studies, group feeding therapy approaches, sensory-based interventions, qualitative research, and higher level study designs. Knowledge translation (KT) activities focused on helping the collaborator improve service delivery of the SOS method and data collection on its effectiveness. Current caregiver/parent education materials were modified to increase accessibility for families to track their child’s progress at home, and a home documentation log was created to facilitate more robust progress tracking over time. Generalizable conclusions about the effectiveness of each KT activity cannot be drawn due to the small sample size of feedback providers. However, feedback received indicates the home documentation log was understandable and easy to use for caregivers/parents, and an effective progress monitoring tool for the collaborator. Collaborator feedback also indicated increased accessibility of caregiver/parent education materials. This suggests potential for home documentation and caregiver/parent education materials to facilitate increased progress tracking and understanding of the SOS feeding approach

Early neutrophil trajectory following clozapine may predict clozapine response - Results from an observational study using electronic health records

Background: Clozapine has unique effectiveness in treatment-resistant schizophrenia and is known to cause immunological side-effects. A transient spike in neutrophils commonly occurs in the first weeks of clozapine therapy. There is contradictory evidence in the literature as to whether neutrophil changes with clozapine are linked to treatment response. Aims: The current study aims to further examine the neutrophil changes in response to clozapine and explore any association between neutrophil trajectory and treatment response. Methods: A retrospective cohort study of patients undergoing their first treatment with clozapine and continuing for at least 2 years identified 425 patients (69% male/31% female). Neutrophil counts at baseline, 3 weeks and 1 month were obtained predominantly by linkage with data from the clozapine monitoring service. Clinical Global Impression- Severity (CGI-S) was rated from case notes at the time of clozapine initiation and at 2 years. Latent class growth analysis (LCGA) was performed to define distinct trajectories of neutrophil changes during the first month of treatment. Logistic regression was then conducted to investigate for association between the trajectory of neutrophil count changes in month 1 and clinical response at 2 years as well as between baseline neutrophil count and response. Results: Of the original cohort, 397 (93%) patients had useable neutrophil data during the first 6 weeks of clozapine treatment. LCGA revealed significant differences in neutrophil trajectories with a three-class model being the most parsimonious. The classes had similar trajectory profiles but differed primarily on overall neutrophil count: with low, high-normal and high neutrophil classes, comprising 52%, 40% and 8% of the sample respectively. Membership of the high-normal group was associated with significantly increased odds of a positive response to clozapine, as compared to the low neutrophil group [Odds ratio (OR) = 2.10, p-value = 0.002; 95% confidence interval (95% CI) = 1.31–3.36]. Baseline neutrophil count was a predictor of response to clozapine at 2 years, with counts of ≥5 × 109/l significantly associated with positive response (OR = 1.60, p-value = 0.03; 95% CI = 1.03–2.49). Conclusions: Our data are consistent with the hypothesis that patients with low-level inflammation, reflected in a high-normal neutrophil count, are more likely to respond to clozapine, raising the possibility that clozapine exerts its superior efficacy via immune mechanisms.</p

Algunos aspectos lingüísticos de los debates electorales Zapatero-Rajoy 2008

Dada la escasa tradición de los debates políticos electorales en España, el que ha tenido lugar este año entre Rodríguez Zapatero y Rajoy reviste singular importancia. Desde la perspectiva del lenguaje político (que se proyecta sobre el periodístico), conviene analizar lo más sobresaliente de su contenido para examinar aquellos puntos peculiares (que se ponen al servicio de la persuasión y la propaganda). Este análisis es realizado en el nivel sintáctico (empleo de deícticos, estructuras repetitivas y esquemas ordenadores) y semántico (eufemismos, metáforas, palabras símbolo y valoración de la sufijación).Given the lack of tradition in Spain for presidential debates, the one which took place earlier this year between Rodríguez Zapatero and Rajoy is of great importance. From the perspective of political language (seen trough the journalistic language), it would be convenient to analyse the most important details from its content in orden to examine those special points (which are at the service of persuasion and propaganda). This anlysis is carried out on a syntactic level (use of deictic, repetitive structures and ordering schemes) and on a semantic level (euphemisms, metaphors, symbol words and valuation of suffixation)

Factors and considerations for establishing and improving seasonal influenza vaccination of health workers: Report from a WHO meeting, January 16-17, Berlin, Germany

Health workers represent an important target group for seasonal influenza vaccination because of their increased risk of infection as well as the risk of transmitting infection to vulnerable patients in the health care setting. Moreover, seasonal vaccination of health workers contributes to pandemic preparedness. However, many countries, especially in Africa and Asia, do not have policies for health worker influenza vaccination. In countries where such policies exist, vaccination coverage is often low. The World Health Organization (WHO) is developing a manual to guide the introduction of seasonal influenza vaccination of health workers. An Independent External Advisory Group (IEAG) that is advising WHO on the content of the manual met to discuss issues that are relevant and often unique to health worker vaccination. This meeting report summarizes the main issues that were discussed and the outcomes of the discussion. The issues include policy considerations, including the evidence in support of health worker vaccination; categorization and prioritization of health workers; the choice of vaccination strategy; its integration into broader health worker vaccination and occupational health policies; planning and management of vaccination, particularly the approaches for communication and demand generation; and the challenges with monitoring and evaluation of health worker vaccination, especially in low and middle-income countries