Small intestinal presentation of nodular lymphocyte-predominant Hodgkin lymphoma with T cell/histiocyte-rich B cell lymphoma-like areas—with review of literature on extranodal presentation of this disease

Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL), accounts for ∼5% of all cases of Hodgkin lymphoma and is characterized by involvement of the peripheral lymph nodes. NLPHL occurs in young adults and is associated with frequent relapses. In 3% to 7% of cases, NLPHL progresses to a diffuse large B cell lymphoma. Furthermore, a proportion of NLPHL also have areas with features of T cell/histiocyte-rich large B cell lymphoma (THRLBCL), either at presentation or on follow-up. Here, we describe a 32-year-old man who presented to the emergency department with small bowel perforation. The resected small bowel showed full-thickness mural ulceration and involvement by a lymphoma with features of NLPHL that also had areas resembling THRLBCL. The patient had axillary lymphadenopathy, biopsy of which showed NLPHL with focal THRLBCL-like areas. Such a lymphoma presenting as small intestinal lesion/perforation has not been reported in the literature before. We take this opportunity to review the literature on extranodal presentations of NLPHL and discuss the natural history of this disease

Dynamics and Transport in the Middle Atmosphere Using Remote Sensing Techniques from Ground and Space

International audienceThe middle atmosphere is generally defined as the region of the atmosphere located between the tropopause (8–17 km) and the mesopause (85–90 km). It includes the stratosphere, where the ozone layer takes place, and the mesosphere. The temperature and wind structure of this region is mainly driven by radiative processes (mainly on of solar radiation by ozone and infrared cooling by CO2) and dynamic processes (propagation and breaking of planetary and gravity waves, meridional circulation from equator to poles in the stratosphere, and from summer pole to winter pole in the mesosphere). A good knowledge of these processes is required to understand the transport of constituents playing a role in the photochemistry of stratospheric ozone and the heat budget of the middle atmosphere determining its thermal structure. In-situ measurements at these high altitudes are not easy to perform and several remote sensing techniques have been developed to observe these regions from the ground and from space, among them infrasound measurement is a promising one. This article presents the main characteristics of dynamics and transport in the middle atmosphere and gives a review of the remote sensing techniques used to observe this region in complement to infrasound detection: lidars, radars, infrared and microwave sounders, and GNSS radio-occultation

Bone marrow in Hodgkin lymphoma and mimickers.

the chapter describes the features of bone marrow involvement by Hodgkin lymphom