1,328 research outputs found
Moral reasoning and homosexuality: the acceptability of arguments about lesbian and gay issues
In the political arena, lesbian and gay issues have typically been contested on grounds of human rights, but with variable success. Using a moral developmental framework, the purpose of this study was to explore preferences for different types of moral arguments when thinking about moral dilemmas around lesbian and gay issues. The analysis presented here comprised data collected from 545 students at UK universities, who completed a questionnaire, part of which comprised a moral dilemma task. Findings of the study showed that respondents do not apply moral reasoning consistently, and do not (clearly) favour human rights reasoning when thinking about lesbian and gay issues. Respondents tended to favour reasoning supporting existing social structures and frameworks, therefore this study highlights the importance of structural change in effecting widespread attitude change in relation to lesbian and gay rights issues. The implications of the findings for moral education are also discussed.</p
Exponential martingales and changes of measure for counting processes
We give sufficient criteria for the Dol\'eans-Dade exponential of a
stochastic integral with respect to a counting process local martingale to be a
true martingale. The criteria are adapted particularly to the case of counting
processes and are sufficiently weak to be useful and verifiable, as we
illustrate by several examples. In particular, the criteria allow for the
construction of for example nonexplosive Hawkes processes as well as counting
processes with stochastic intensities depending on diffusion processes
In-situ velocity imaging of ultracold atoms using slow--light
The optical response of a moving medium suitably driven into a slow-light
propagation regime strongly depends on its velocity. This effect can be used to
devise a novel scheme for imaging ultraslow velocity fields. The scheme turns
out to be particularly amenable to study in-situ the dynamics of collective and
topological excitations of a trapped Bose-Einstein condensate. We illustrate
the advantages of using slow-light imaging specifically for sloshing
oscillations and bent vortices in a stirred condensate
RNA-seq and Tn-seq reveal fitness determinants of vancomycin-resistant Enterococcus faecium during growth in human serum
BACKGROUND: The Gram-positive bacterium Enterococcus faecium is a commensal of the human gastrointestinal tract and a frequent cause of bloodstream infections in hospitalized patients. The mechanisms by which E. faecium can survive and grow in blood during an infection have not yet been characterized. Here, we identify genes that contribute to growth of E. faecium in human serum through transcriptome profiling (RNA-seq) and a high-throughput transposon mutant library sequencing approach (Tn-seq). RESULTS: We first sequenced the genome of E. faecium E745, a vancomycin-resistant clinical isolate, using a combination of short- and long read sequencing, revealing a 2,765,010 nt chromosome and 6 plasmids, with sizes ranging between 9.3 kbp and 223.7 kbp. We then compared the transcriptome of E. faecium E745 during exponential growth in rich medium and in human serum by RNA-seq. This analysis revealed that 27.8% of genes on the E. faecium E745 genome were differentially expressed in these two conditions. A gene cluster with a role in purine biosynthesis was among the most upregulated genes in E. faecium E745 upon growth in serum. The E. faecium E745 transposon mutant library was then used to identify genes that were specifically required for growth of E. faecium in serum. Genes involved in de novo nucleotide biosynthesis (including pyrK_2, pyrF, purD, purH) and a gene encoding a phosphotransferase system subunit (manY_2) were thus identified to be contributing to E. faecium growth in human serum. Transposon mutants in pyrK_2, pyrF, purD, purH and manY_2 were isolated from the library and their impaired growth in human serum was confirmed. In addition, the pyrK_2 and manY_2 mutants were tested for their virulence in an intravenous zebrafish infection model and exhibited significantly attenuated virulence compared to E. faecium E745. CONCLUSIONS: Genes involved in carbohydrate metabolism and nucleotide biosynthesis of E. faecium are essential for growth in human serum and contribute to the pathogenesis of this organism. These genes may serve as targets for the development of novel anti-infectives for the treatment of E. faecium bloodstream infections
Определение оптимальных параметров источника рентгеновского излучения на базе малогабаритного ускорителя электронов
Проведено моделирование спектров рентгеновского излучения, генерируемого электронами с энергией 4…10 МэВ в мишенях из различных материалов и разной толщины. Определены оптимальные параметры мишени-конвертора для использования ее в медицинских источниках монохроматического рентгеновского излучения на базе малогабаритных электронных ускорителей. Проведены оценки интенсивности излучения и сравнение источников на базе разных ускорителей
Temperature and Frequency Dependence of Complex Conductance of Ultrathin YBa2Cu3O7-x Films: A Study of Vortex-Antivortex Pair Unbinding
We have studied the temperature dependencies of the complex sheet conductance
of 1-3 unit cell (UC) thick YBa2Cu3O7-x films sandwiched between semiconducting
Pr0.6Y0.4Ba2Cu3O7-x layers at high frequencies. Experiments have been carried
out in a frequency range between: 2 - 30 MHz with one-spiral coil technique,
100 MHz - 1 GHz frequency range with a new technique using the spiral coil
cavity and at 30 GHz by aid of a resonant cavity technique. The real and
imaginary parts of the mutual-inductance between a coil and a film were
measured and converted to complex conductivity by aid of the inversion
procedure. We have found a quadratic temperature dependence of the kinetic
inductance, L_k^-1(T), at low temperatures independent of frequency, with a
break in slope at T^dc_BKT, the maximum of real part of conductance and a large
shift of the break temperature and the maximum position to higher temperatures
with increasing frequency. We obtain from these data the universal ratio
T^dc_BKT/L_k^-1(T^dc_BKT) = 25, 25, and 17 nHK for 1-, 2- and 3UC films,
respectively in close agreement with theoretical prediction of 12 nHK for
vortex-antivortex unbinding transition. The activated temperature dependence of
the vortex diffusion constant was observed and discussed in the framework of
vortex-antivortex pair pinning.
PACS numbers: 74.80.Dm, 74.25.Nf, 74.72.Bk, 74.76.BzComment: PDF file, 10 pages, 6 figures, to be published in J. Low Temp. Phys.;
Proc. of NATO ARW: VORTEX 200
ASTEC -- the Aarhus STellar Evolution Code
The Aarhus code is the result of a long development, starting in 1974, and
still ongoing. A novel feature is the integration of the computation of
adiabatic oscillations for specified models as part of the code. It offers
substantial flexibility in terms of microphysics and has been carefully tested
for the computation of solar models. However, considerable development is still
required in the treatment of nuclear reactions, diffusion and convective
mixing.Comment: Astrophys. Space Sci, in the pres
First Stars. I. Evolution without mass loss
The first generation of stars was formed from primordial gas. Numerical
simulations suggest that the first stars were predominantly very massive, with
typical masses M > 100 Mo. These stars were responsible for the reionization of
the universe, the initial enrichment of the intergalactic medium with heavy
elements, and other cosmological consequences. In this work, we study the
structure of Zero Age Main Sequence stars for a wide mass and metallicity range
and the evolution of 100, 150, 200, 250 and 300 Mo galactic and pregalactic Pop
III very massive stars without mass loss, with metallicity Z=10E-6 and 10E-9,
respectively. Using a stellar evolution code, a system of 10 equations together
with boundary conditions are solved simultaneously. For the change of chemical
composition, which determines the evolution of a star, a diffusion treatment
for convection and semiconvection is used. A set of 30 nuclear reactions are
solved simultaneously with the stellar structure and evolution equations.
Several results on the main sequence, and during the hydrogen and helium
burning phases, are described. Low metallicity massive stars are hotter and
more compact and luminous than their metal enriched counterparts. Due to their
high temperatures, pregalactic stars activate sooner the triple alpha reaction
self-producing their own heavy elements. Both galactic and pregalactic stars
are radiation pressure dominated and evolve below the Eddington luminosity
limit with short lifetimes. The physical characteristics of the first stars
have an important influence in predictions of the ionizing photon yields from
the first luminous objects; also they develop large convective cores with
important helium core masses which are important for explosion calculations.Comment: 17 pages, 24 figures, 2 table
pQCD Physics of multiparton interactions
We study production of two pairs of jets in %hard hadron--hadron collisions
in view of extracting contribution of {\em double hard interactions} of three
and four partons (, ). Such interactions, in spite of being power
suppressed at the level of the total cross section, become comparable with the
standard hard collisions of two partons, , in the {\em back-to-back
kinematics} when the transverse momentum imbalances of two pairing jets are
relatively small.
We express differential and total cross sections for two-dijet production in
double parton collisions through the generalized two-parton distributions,
GPDs \cite{BDFS1}, that contain large-distance two-parton correlations of
non-perturbative origin as well as small-distance correlations due to parton
evolution. We find that these large- and small-distance correlations
participate in different manner in 4-jet production, and treat them in the
leading logarithmic approximation of pQCD that resums collinear logarithms in
all orders.
A special emphasis is given to double hard interaction processes that
occur as an interplay between large- and short-distance parton correlations and
were not taken into consideration by approaches inspired by the parton model
picture. We demonstrate that the mechanism, being of the same order in
\as as the process, turns out to be {\em geometrically enhanced}
compared to the latter and should contribute significantly to 4-jet production.
The framework developed here takes into systematic consideration perturbative
evolution of GPDs. It can be used as a basis for future analysis of
NLO corrections to multi-parton interactions (MPI) at LHC and Tevatron
colliders, in particular for improving evaluation of QCD backgrounds to new
physics searches.Comment: 16 pages,4 figures Improved presentation; list of references
reworked; qualitative estimate of the magnitude of different contributions in
the beck-to- back region correcte
Politieke kennis en effecten van nieuws
Welk nieuws doet ertoe en hoeveel nieuws doet ertoe, en in welke mate hangt dit af van de politieke kennis van de ontvanger? Dit artikel beschrijft een longitudinale studie naar de verkiezingsstrijd voor het Nederlandse parlement in 2006
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