9,225 research outputs found

    PIN50: VALIDATION OF THE HEALTH RELATED PRODUCTIVITY QUESTIONNAIRE DIARY (HRPQ-D) ON A SAMPLE OF PATIENTS WITH INFECTIOUS MONONUCLEOSIS: RESULTS FROM AN OBSERVATIONAL STUDY

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    A Sharp Inequality of Markov Type for Polynomials Associated with Laguerre Weight

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    AbstractThe best possible constant An in an inequality of Markov type [ddx(e−xpn(x))][0, ∞)⩽An‖e−xpn(x)‖[0, ∞), where ‖·‖[0, ∞) denotes the sup-norm on the half real line [0, ∞) and pn is an arbitrary polynomial of degree at most n, is determined in terms of the weighted Chebyshev polynomials associated with the Laguerre weight e−x on [0, ∞)

    Resilience and Quality of Life in Taiwanese Survivors of Childhood Cancer

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    Survivors of childhood cancer are at risk to develop physiologic-psychosocial complications that affect their quality of life. This study explored how the independent variables of illness-related risk (ILLRK), individual risks (IRK), protective factors (PF) and resilience (RS) affected the dependent variable---quality of life (QOL)--in Taiwanese survivors of childhood cancer. Triangulated research methodology was employed to (1) identify the statistical relationships between the variables and (2) explore qualitatively what these variables meant to the subjects and how their perceptions further explained the statistical results. Haase\u27s (2004) Adolescent Resilience Model was used as the theoretical framework. Ninety-eight Taiwanese adolescent cancer survivors, diagnosed with brain tumors or leukemia before the age of 16 years, surviving at least 5 years after diagnosis, were recruited. From this sample, 12 were selected for the interview segment. Four valid and reliable Likert-scale instruments were used to assess the variables, while a semi-structured interview format was used for the qualitative component. Descriptive statistics, ANOVA, and multiple regressions were used to describe the sample, and analyze the data. Analysis of the interview data looked for recurring themes. Quantitative findings: (1) statistical significance (p \u3c .001) between the QOL in survivors of brain tumor and leukemia; (2) statistically positive relationships (p \u3c .001) between PF, RS, and QOL; (3) statistically negative relationships (p \u3c .001) between ILLRK, IRK and QOL. The significant predictors affecting QOL were ILLRK, IRK, RS and cancer types. Qualitative findings: (1) theme of loss of self explained IRK; (2) chronic fear explained ILLRK; (3) good sense of self explained PF; (4) rebounding even using less than optimal coping strategies explained RS; (5) control of one\u27s life explained QOL. Culture influenced ones sense of self and control. Resilience is critical to achieving optimal quality of life. Protective factors can predict type of resilience and quality of life. Interventions to enhance protective factors are critical. Cancer type also contributes to lower QOL. Different interventions for brain tumors or leukemia survivors must be considered. Cultural beliefs and practices can influence how survivors interpret risks, resilience, and quality of life. These results can support nursing efforts to effect changes in health policy, nursing education, and nursing practice in Taiwan

    Two Simple W' Models for the Early LHC

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    W' gauge bosons are good candidates for early LHC discovery. We define two reference models, one containing a W'_R and one containing a W'_L, which may serve as ``simplified models'' for presenting experimental results of W' searches at the LHC. We present the Tevatron bounds on each model and compute the constraints from precision electroweak observables. We find that indirect low-energy constraints on the W'_L are quite strong. However, for a W'_R coupling to right-handed fermions there exists a sizeable region in parameter space beyond the bounds from the Tevatron and low-energy precision measurements where even 50 inverse picobarns of integrated LHC luminosity are sufficient to discover the W'_R. The most promising final states are two leptons and two jets, or one lepton recoiling against a ``neutrino jet''. A neutrino jet is a collimated object consisting of a hard lepton and two jets arising from the decay of a highly boosted massive neutrino.Comment: 20 pages, 8 figures. v2: references adde

    Trends for nanotechnology development in China, Russia, and India

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    China, Russia, and India are playing an increasingly important role in global nanotechnology research and development (R&D). This paper comparatively inspects the paper and patent publications by these three countries in the Thomson Science Citation Index Expanded (SCI) database and United States Patent and Trademark Office (USPTO) database (1976–2007). Bibliographic, content map, and citation network analyses are used to evaluate country productivity, dominant research topics, and knowledge diffusion patterns. Significant and consistent growth in nanotechnology papers are noted in the three countries. Between 2000 and 2007, the average annual growth rate was 31.43% in China, 11.88% in Russia, and 33.51% in India. During the same time, the growth patterns were less consistent in patent publications: the corresponding average rates are 31.13, 10.41, and 5.96%. The three countries’ paper impact measured by the average number of citations has been lower than the world average. However, from 2000 to 2007, it experienced rapid increases of about 12.8 times in China, 8 times in India, and 1.6 times in Russia. The Chinese Academy of Sciences (CAS), the Russian Academy of Sciences (RAS), and the Indian Institutes of Technology (IIT) were the most productive institutions in paper publication, with 12,334, 6,773, and 1,831 papers, respectively. The three countries emphasized some common research topics such as “Quantum dots,” “Carbon nanotubes,” “Atomic force microscopy,” and “Scanning electron microscopy,” while Russia and India reported more research on nano-devices as compared with China. CAS, RAS, and IIT played key roles in the respective domestic knowledge diffusion

    SU(7) Unification of SU(3)_C*SU(4)_W* U(1)_{B-L}

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    We propose the SUSY SU(7) unification of the SU(3)_C* SU(4)_W* U(1)_{B-L} model. Such unification scenario has rich symmetry breaking chains in a five-dimensional orbifold. We study in detail the SUSY SU(7) symmetry breaking into SU(3)_C* SU(4)_W* U(1)_{B-L} by boundary conditions in a Randall-Sundrum background and its AdS/CFT interpretation. We find that successful gauge coupling unification can be achieved in our scenario. Gauge unification favors low left-right and unification scales with tree-level \sin^2\theta_W=0.15. We use the AdS/CFT dual of the conformal supersymmetry breaking scenario to break the remaining N=1 supersymmetry. We employ AdS/CFT to reproduce the NSVZ formula and obtain the structure of the Seiberg duality in the strong coupling region for 3/2N_c<N_F<3N_C. We show that supersymmetry is indeed broken in the conformal supersymmetry breaking scenario with a vanishing singlet vacuum expectation value.Comment: 25 pages, 1 figure

    Genomic signatures of population decline in the malaria mosquito Anopheles gambiae

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    Population genomic features such as nucleotide diversity and linkage disequilibrium are expected to be strongly shaped by changes in population size, and might therefore be useful for monitoring the success of a control campaign. In the Kilifi district of Kenya, there has been a marked decline in the abundance of the malaria vector Anopheles gambiae subsequent to the rollout of insecticide-treated bed nets. To investigate whether this decline left a detectable population genomic signature, simulations were performed to compare the effect of population crashes on nucleotide diversity, Tajima's D, and linkage disequilibrium (as measured by the population recombination parameter ρ). Linkage disequilibrium and ρ were estimated for An. gambiae from Kilifi, and compared them to values for Anopheles arabiensis and Anopheles merus at the same location, and for An. gambiae in a location 200 km from Kilifi. In the first simulations ρ changed more rapidly after a population crash than the other statistics, and therefore is a more sensitive indicator of recent population decline. In the empirical data, linkage disequilibrium extends 100-1000 times further, and ρ is 100-1000 times smaller, for the Kilifi population of An. gambiae than for any of the other populations. There were also significant runs of homozygosity in many of the individual An. gambiae mosquitoes from Kilifi. These results support the hypothesis that the recent decline in An. gambiae was driven by the rollout of bed nets. Measuring population genomic parameters in a small sample of individuals before, during and after vector or pest control may be a valuable method of tracking the effectiveness of interventions

    The Maximal U(1)LU(1)_L Inverse Seesaw from d=5d=5 Operator and Oscillating Asymmetric Sneutrino Dark Matter

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    The maximal U(1)LU(1)_L supersymmetric inverse seesaw mechanism (MLLSIS) provides a natural way to relate asymmetric dark matter (ADM) with neutrino physics. In this paper we point out that, MLLSIS is a natural outcome if one dynamically realizes the inverse seesaw mechanism in the next-to minimal supersymmetric standard model (NMSSM) via the dimension-five operator (N)2S2/M(N)^2S^2/M_*, with SS the NMSSM singlet developing TeV scale VEV; it slightly violates lepton number due to the suppression by the fundamental scale MM_*, thus preserving U(1)LU(1)_L maximally. The resulting sneutrino is a distinguishable ADM candidate, oscillating and favored to have weak scale mass. A fairly large annihilating cross section of such a heavy ADM is available due to the presence of singlet.Comment: journal versio

    PainDroid: An android-based virtual reality application for pain assessment

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    Earlier studies in the field of pain research suggest that little efficient intervention currently exists in response to the exponential increase in the prevalence of pain. In this paper, we present an Android application (PainDroid) with multimodal functionality that could be enhanced with Virtual Reality (VR) technology, which has been designed for the purpose of improving the assessment of this notoriously difficult medical concern. Pain- Droid has been evaluated for its usability and acceptability with a pilot group of potential users and clinicians, with initial results suggesting that it can be an effective and usable tool for improving the assessment of pain. Participant experiences indicated that the application was easy to use and the potential of the application was similarly appreciated by the clinicians involved in the evaluation. Our findings may be of considerable interest to healthcare providers, policy makers, and other parties that might be actively involved in the area of pain and VR research
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