146 research outputs found
Search for a Technicolor omega_T Particle in Events with a Photon and a b-quark Jet at CDF
If the Technicolor omega_T particle exists, a likely decay mode is omega_T ->
gamma pi_T, followed by pi_T -> bb-bar, yielding the signature gamma bb-bar. We
have searched 85 pb^-1 of data collected by the CDF experiment at the Fermilab
Tevatron for events with a photon and two jets, where one of the jets must
contain a secondary vertex implying the presence of a b quark. We find no
excess of events above standard model expectations. We express the result of an
exclusion region in the M_omega_T - M_pi_T mass plane.Comment: 14 pages, 2 figures. Available from the CDF server (PS with figs):
http://www-cdf.fnal.gov/physics/pub98/cdf4674_omega_t_prl_4.ps
FERMILAB-PUB-98/321-
Measurement of the B0 anti-B0 oscillation frequency using l- D*+ pairs and lepton flavor tags
The oscillation frequency Delta-md of B0 anti-B0 mixing is measured using the
partially reconstructed semileptonic decay anti-B0 -> l- nubar D*+ X. The data
sample was collected with the CDF detector at the Fermilab Tevatron collider
during 1992 - 1995 by triggering on the existence of two lepton candidates in
an event, and corresponds to about 110 pb-1 of pbar p collisions at sqrt(s) =
1.8 TeV. We estimate the proper decay time of the anti-B0 meson from the
measured decay length and reconstructed momentum of the l- D*+ system. The
charge of the lepton in the final state identifies the flavor of the anti-B0
meson at its decay. The second lepton in the event is used to infer the flavor
of the anti-B0 meson at production. We measure the oscillation frequency to be
Delta-md = 0.516 +/- 0.099 +0.029 -0.035 ps-1, where the first uncertainty is
statistical and the second is systematic.Comment: 30 pages, 7 figures. Submitted to Physical Review
Alcohol consumers’ attention to warning labels and brand information on alcohol packaging: Findings from cross-sectional and experimental studies
Background
Alcohol warning labels have a limited effect on drinking behavior, potentially because people devote minimal attention to them. We report findings from two studies in which we measured the extent to which alcohol consumers attend to warning labels on alcohol packaging, and aimed to identify if increased attention to warning labels is associated with motivation to change drinking behavior.
Methods
Study 1 (N = 60) was an exploratory cross-sectional study in which we used eye-tracking to measure visual attention to brand and health information on alcohol and soda containers. In study 2 (N = 120) we manipulated motivation to reduce drinking using an alcohol brief intervention (vs control intervention) and measured heavy drinkers’ attention to branding and warning labels with the same eye-tracking paradigm as in study 1. Then, in a separate task we experimentally manipulated attention by drawing a brightly colored border around health (or brand) information before measuring participants’ self-reported drinking intentions for the subsequent week.
Results
Study 1 showed that participants paid minimal attention to warning labels (7% of viewing time). Participants who were motivated to reduce drinking paid less attention to alcohol branding and alcohol warning labels. Results from study 2 showed that the alcohol brief intervention decreased attention to branding compared to the control condition, but it did not affect attention to warning labels. Furthermore, the experimental manipulation of attention to health or brand information did not influence drinking intentions for the subsequent week.
Conclusions
Alcohol consumers allocate minimal attention to warning labels on alcohol packaging and even if their attention is directed to these warning labels, this has no impact on their drinking intentions. The lack of attention to warning labels, even among people who actively want to cut down, suggests that there is room for improvement in the content of health warnings on alcohol packaging
Two Host Factors Regulate Persistence of H7a-Specific T Cells Injected in Tumor-Bearing Mice
BACKGROUND: Injection of CD8 T cells primed against immunodominant minor histocompatibility antigens (MiHA) such as H7(a) can eradicate leukemia and solid tumors. To understand why MiHA-targeted T cells have such a potent antitumor effect it is essential to evaluate their in vivo behavior. In the present work, we therefore addressed two specific questions: what is the proliferative dynamics of H7(a)-specifc T cells in tumors, and do H7(a)-specific T cells persist long-term after adoptive transfer? METHODOLOGY/PRINCIPAL FINDINGS: By day 3 after adoptive transfer, we observed a selective infiltration of melanomas by anti-H7(a) T cells. Over the next five days, anti-H7(a) T cells expanded massively in the tumor but not in the spleen. Thus, by day 8 after injection, anti-H7(a) T cells in the tumor had undergone more cell divisions than those in the spleen. These data strongly suggest that anti-H7(a) T cells proliferate preferentially and extensively in the tumors. We also found that two host factors regulated long-term persistence of anti-H7(a) memory T cells: thymic function and expression of H7(a) by host cells. On day 100, anti-H7(a) memory T cells were abundant in euthymic H7(a)-negative (B10.H7(b)) mice, present in low numbers in thymectomized H7(a)-positive (B10) hosts, and undetectable in euthymic H7(a)-positive recipients. CONCLUSIONS/SIGNIFICANCE: Although in general the tumor environment is not propitious to T-cell invasion and expansion, the present work shows that this limitation may be overcome by adoptive transfer of primed CD8 T cells targeted to an immunodominant MiHA (here H7(a)). At least in some cases, prolonged persistence of adoptively transferred T cells may be valuable for prevention of late cancer relapse in adoptive hosts. Our findings therefore suggest that it may be advantageous to target MiHAs with a restricted tissue distribution in order to promote persistence of memory T cells and thereby minimize the risk of cancer recurrence
Search for second generation leptoquarks in the dimuon plus dijet channel of p-pbar collisions at sqrt{s}=1.8 TeV
We report on a search for second generation leptoquarks (Phi_2) using a data
sample corresponding to an integrated luminosity of 110 pb^{-1} collected at
the Collider Detector at Fermilab. We present upper limits on the production
cross section as a function of Phi_2 mass, assuming that the leptoquarks are
produced in pairs and decay into a muon and a quark with branching ratio beta.
Using a Next-to-Leading order QCD calculation, we extract a lower mass limit of
M_{\Phi_2} > 202 (160) GeV$/c^{2} at 95% confidence level for scalar
leptoquarks with beta=1(0.5).Comment: 11 pages, 2 figure
Search for New Particles Decaying to b bbar in p pbar Collisions at sqrt{s}=1.8 TeV
We have used 87 pb^-1 of data collected with the Collider Detector at
Fermilab to search for new particles decaying to b bbar. We present
model-independent upper limits on the cross section for narrow resonances which
excludes the color-octet technirho in the mass interval 350 < M < 440 GeV/c^2.
In addition, we exclude topgluons, predicted in models of topcolor-assisted
technicolor, of width Gamma = 0.3 M in the mass range 280 < M < 670 GeV/c^2, of
width Gamma = 0.5 M in the mass range 340 < M < 640 GeV/c^2, and of width Gamma
= 0.7 M in the mass range 375 < M < 560 GeV/c^2.Comment: 17 pages in a LaTex generated postscript file, with one table and
four figures. Resubmitted to Physical Review Letters. Minor clarifications
were added to the text. The displayed normalization of the resonance models
in Figure 2 was modified to correspond to our 95% CL upper limit on the cross
section (instead of arbitrary normalization which was used previously). All
results are identical to those in the previous submissio
Search for a W' Boson via the Decay Mode W' -> mu nu in 1.8 TeV p-pbar Collisions
We report the results of a search for a W' boson produced in p-pbar
collisions at a center-of-mass energy of 1.8 TeV using a 107 pb-1 data sample
recorded by the Collider Detector at Fermilab. We consider the decay channel W'
-> mu nu and search for anomalous production of high transverse mass mu-nu
lepton pairs. We observe no excess of events above background and set limits on
the rate of W' boson production and decay relative to Standard Model W boson
production and decay using a fit of the transverse mass distribution observed.
If we assume Standard Model strength couplings of the W' boson to quark and
lepton pairs, we exclude a W' boson with invariant mass less than 660 GeV/c**2
at 95% confidence level.Comment: 19 pages, 2 figure
Impact of pretransplant conditioning and donor T cells on chimerism, graft-versus-host disease, graft-versus-leukemia reactivity, and tolerance after bone marrow transplantation
Impact of pretransplant conditioning and donor T cells on chimerism, graft-versus-host disease, graft-versus-leukemia reactivity, and tolerance after bone marrow transplantation
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