34 research outputs found
Circumstellar disks and planets. Science cases for next-generation optical/infrared long-baseline interferometers
We present a review of the interplay between the evolution of circumstellar
disks and the formation of planets, both from the perspective of theoretical
models and dedicated observations. Based on this, we identify and discuss
fundamental questions concerning the formation and evolution of circumstellar
disks and planets which can be addressed in the near future with optical and
infrared long-baseline interferometers. Furthermore, the importance of
complementary observations with long-baseline (sub)millimeter interferometers
and high-sensitivity infrared observatories is outlined.Comment: 83 pages; Accepted for publication in "Astronomy and Astrophysics
Review"; The final publication is available at http://www.springerlink.co
The effector T cell response to influenza infection
Influenza virus infection induces a potent initial innate immune response, which serves to limit the extent of viral replication and virus spread. However, efficient (and eventual) viral clearance within the respiratory tract requires the subsequent activation, rapid proliferation, recruitment, and expression of effector activities by the adaptive immune system, consisting of antibody producing B cells and influenza-specific T lymphocytes with diverse functions. The ensuing effector activities of these T lymphocytes ultimately determine (along with antibodies) the capacity of the host to eliminate the viruses and the extent of tissue damage. In this review, we describe this effector T cell response to influenza virus infection. Based on information largely obtained in experimental settings (i.e., murine models), we will illustrate the factors regulating the induction of adaptive immune T cell responses to influenza, the effector activities displayed by these activated T cells, the mechanisms underlying the expression of these effector mechanisms, and the control of the activation/differentiation of these T cells, in situ, in the infected lungs
Multiple uses of fibrin sealant for nervous system treatment following injury and disease
Radial gradients in initial mass function sensitive absorption features in the Coma brightest cluster galaxies
Using the Oxford ShortWavelength Integral Field specTrograph, we trace radial variations of initial mass function (IMF)-sensitive absorption features of three galaxies in the Coma cluster. We obtain resolved spectroscopy of the central 5 kpc for the two central brightest cluster galaxies (BCGs) NGC4889, NGC4874, and the BCG in the south-west group NGC4839, as well as unresolved data for NGC4873 as a low-σ* control.We present radial measurements of the IMF-sensitive features: sodium Na I SDSS , calcium triplet CaT, and iron-hydride FeH0.99, along with the magnesium Mg I0.88 and titanium oxide TiO0.89 features. We employ two separate methods for both telluric correction and sky subtraction around the faint FeH feature to verify our analysis. Within NGC4889 we find strong gradients of Na I SDSS and CaT but a flat FeH profile, which, from comparing to stellar population synthesis models, suggests an old, α-enhanced population with a Chabrier, or even bottom-light IMF. The age and abundance are in line with previous studies but the normal IMF is in contrast to recent results suggesting an increased IMF slope with increased velocity dispersion.We measure flat Na I SDSS and FeH profiles within NGC4874, and determine an old, possibly slightly α-enhanced and Chabrier IMF population. We find an α-enhanced, Chabrier IMF population in NGC4873. Within NGC4839 we measure both strong Na I SDSS and strong FeH, although with a large systematic uncertainty, suggesting a possible heavier IMF. The IMFswe infer for these galaxies are supported by published dynamical modelling. We stress that IMF constraints should be corroborated by further spectral coverage and independent methods on a galaxy-by-galaxy basis
Radial gradients in initial mass function sensitive absorption features in the Coma brightest cluster galaxies
Using the Oxford ShortWavelength Integral Field specTrograph, we trace radial variations of initial mass function (IMF)-sensitive absorption features of three galaxies in the Coma cluster. We obtain resolved spectroscopy of the central 5 kpc for the two central brightest cluster galaxies (BCGs) NGC4889, NGC4874, and the BCG in the south-west group NGC4839, as well as unresolved data for NGC4873 as a low-σ* control.We present radial measurements of the IMF-sensitive features: sodium Na I SDSS , calcium triplet CaT, and iron-hydride FeH0.99, along with the magnesium Mg I0.88 and titanium oxide TiO0.89 features. We employ two separate methods for both telluric correction and sky subtraction around the faint FeH feature to verify our analysis. Within NGC4889 we find strong gradients of Na I SDSS and CaT but a flat FeH profile, which, from comparing to stellar population synthesis models, suggests an old, α-enhanced population with a Chabrier, or even bottom-light IMF. The age and abundance are in line with previous studies but the normal IMF is in contrast to recent results suggesting an increased IMF slope with increased velocity dispersion.We measure flat Na I SDSS and FeH profiles within NGC4874, and determine an old, possibly slightly α-enhanced and Chabrier IMF population. We find an α-enhanced, Chabrier IMF population in NGC4873. Within NGC4839 we measure both strong Na I SDSS and strong FeH, although with a large systematic uncertainty, suggesting a possible heavier IMF. The IMFswe infer for these galaxies are supported by published dynamical modelling. We stress that IMF constraints should be corroborated by further spectral coverage and independent methods on a galaxy-by-galaxy basis
The Oxford SWIFT spectrograph: First commissioning and on-sky results
The Oxford SWIFT spectrograph, an I and z band (6500-10500 A) integral field spectrograph, is designed to operate as a facility instrument at the 200 inch Hale Telescope on Palomar Mountain, in conjunction with the Palomar laser guide star adaptive optics system PALAO (and its upgrade to PALM3000). SWIFT provides spectra at R(≡λ/Δλ)∼4000 of a contiguous two-dimensional field, 44 x 89 spatial pixels (spaxels) in size, at spatial scales of 0.235″;, 0.16″, and 0.08″ per spaxel. It employs two 250μm thick, fully depleted, extremely red sensitive 4k X 2k CCD detector arrays (manufactured by LBNL) that provide excellent quantum efficiency out to 1000 nm. We describe the commissioning observations and present the measured values of a number of instrument parameters. We also present some first science results that give a taste of the range of science programs where SWIFT can have a substantial impact. © 2010 Copyright SPIE - The International Society for Optical Engineering
KMOS: Assembly, integration and testing of three 0.8-2.5 micron spectrographs
KMOS is a second generation instrument in construction for use at the European Southern Observatory (ESO) Very Large Telescope (VLT). It operates in the near-infrared (0.8 to 2.5 microns) and employs 24 deployable, image slicing integral field units (IFUs) feeding three spectrographs. The spectrographs are designed and built by a partnership of the University of Oxford and Rutherford Appleton Laboratories (RAL). We describe the assembly, integration and alignment procedures involved in the construction of these spectrographs in detail. We also present the results of the cryogenic optical tests, including the first data taken through the full spectrograph optical train and the details of the test facility and procedures involved. © 2010 Copyright SPIE - The International Society for Optical Engineering
