22 research outputs found
The neurological features of HIV-positive patients in Glasgow - a retrospective study of 90 cases
No full textA retrospective study of the neurological problems arising in HIV-I seropositive patients in a single defined geographical area was undertaken. Ninety patients were referred for a neurological opinion from a total known HIV-I seropositive population of 436. Minor problems were frequently encountered early in the course of disease (20 at CDC stage II, 12 at CDC stage III), including seizures related to drug abuse in six. The most frequent neurological problem in those patients in CDC group IV (58 patients) were the AIDS dementia complex (14 patients), an axonal sensorimotor neuropathy (12), toxoplasmosis (nine) and cryptococcal meningitis (three). All patients with a structural lesion had appropriate focal signs on examination. The value and role of CT cranial scanning in the diagnosis of toxoplasmosis is discussed and the importance of recognizing potentially treatable causes of both intellectual impairment and cytomegalovirus-related neuropathies is stressed. This is the First report of an unselected series of patients at all stages of HIV-I related neurological disease from a single UK centre
The neurological features of HIV-positive patients in Glasgow - a retrospective study of 90 cases
No full textA retrospective study of the neurological problems arising in HIV-I seropositive patients in a single defined geographical area was undertaken. Ninety patients were referred for a neurological opinion from a total known HIV-I seropositive population of 436. Minor problems were frequently encountered early in the course of disease (20 at CDC stage II, 12 at CDC stage III), including seizures related to drug abuse in six. The most frequent neurological problem in those patients in CDC group IV (58 patients) were the AIDS dementia complex (14 patients), an axonal sensorimotor neuropathy (12), toxoplasmosis (nine) and cryptococcal meningitis (three). All patients with a structural lesion had appropriate focal signs on examination. The value and role of CT cranial scanning in the diagnosis of toxoplasmosis is discussed and the importance of recognizing potentially treatable causes of both intellectual impairment and cytomegalovirus-related neuropathies is stressed. This is the First report of an unselected series of patients at all stages of HIV-I related neurological disease from a single UK centre
Sporadic myopathy and exercise intolerance associated with the mitochondrial 8328G>A tRNALys mutation
No full textCatastrophic presentation of mitochondrial disease due to a mutation in the tRNAHis gene
No full text
Partial deficiency of complexes I and IV of the mitochondrial respiratory chain in skeletal muscle of two patients with mitochondrial myopathy
No full textXeroderma Pigmentosum Patients from Germany (the Mannheim XP Collection): Clinical and Biochemical Characteristics
No full textMiopatia mitocondrial relato de 12 casos com estudo histoquÃmico do músculo esquelético
Get PDFSão relatados 12 pacientes com o diagnóstico de MM definidos histoquimicamente. Nove pacientes eram do sexo masculino e três do sexo feminino. A idade de inÃcio dos sintomas variou desde o perÃodo neonatal até os 35 anos de idade (mediana 14 anos). Foram identificadas como caracterÃsticas principais a fraqueza muscular, oftalmoplegia e ptose palpebral em 10 pacientes. Um paciente apresentou quadro de intolerância aos exercÃcios e outro além da fraqueza muscular, alteração do comportamento. São discutidos aspectos clÃnicos e o diagnóstico diferencial de nossos pacientes
