The electrical diagnosis of peripheral nerve injury, and some applications of electronics to physiology and clinical medicine

In the summer of 1941 the Scottish E. M. S. Hospitals organization established a special Unit for the reception and treatment of patients suffering from peripheral nerve injury at Gogarburn Hospital on the outskirts of Edinburgh. In connection with this specialized type of injury, relatively rare in peacetime but assuming considerable importance in War, invitations were issued to various Persons sroecializing in ancillary branches of Medicine and Surgery to attend the clinical meetings of the Peripheral Nerve Unit, to consider applications of their work to this particular problem, and to have access to the patient for the assessment of their methods.Peripheral nerve injury diagnosis and treatment involves a considerable field of application for methods which have been primarily developed as physiological techniques, particularly in the use of modern electrical apparatus, and the Director of the Unit, Professor J. R. Learmonth, invited me to attend the clinical meetings, and to make a study on the patients of modern methods of electrical diagnosis, and this opportunity, gladly accepted, has furnished me with a wealth of problems and of material ever since.This thesis accordingly presents such of these problems as have at present been worked out to the extent of being of clinical or laboratory use

EXTRACELLULAR MATRIX NANOPARTICLES EFFECTS ON THE LUNG IN VIVO

Acute respiratory distress syndrome (ARDS) is a life-threatening condition that causes diffuse alveolar damage and a loss of the extracellular matrix (ECM). This leads to pulmonary edema and lung function deterioration. Our lab has created decellularized porcine lung, electrosprayed ECM nanoparticles that have been previously shown to have pro-regenerative capabilities in vitro. In this study, the ECM nanoparticle effects on young murine lungs were tested in vivo. An ECM nanoparticle suspension, previously used for the in vitro studies, was aerosolized intratracheally into the lungs using a microsprayer. 24 hours later, the lung mechanics, bronchoalveolar lavage fluid, and histology were evaluated. The ECM nanoparticles had no significant damaging effects to the lungs and were comparable to the control groups. Further studies are being done to establish an ARDS model using the ECM nanoparticle treatment

Development of a ductile columbium alloy rocket engine combustion chamber

Development and testing of ductile niobium alloy with silicide coating for rocket engine combustion chambe

Reversible Mode Switching in Y coupled Terahertz Lasers

Electrically independent terahertz (THz) quantum cascade lasers (QCLs) are optically coupled in a Y configuration. Dual frequency, electronically switchable emission is achieved in one QCL using an aperiodic grating, designed using computer-generated hologram techniques, incorporated directly into the QCL waveguide by focussed ion beam milling. Multi-moded emission around 2.9 THz is inhibited, lasing instead occurring at switchable grating-selected frequencies of 2.88 and 2.92 THz. This photonic control and switching behaviour is selectively and reversibly transferred to the second, unmodified QCL via evanescent mode coupling, without the transfer of the inherent grating losses

Y coupled terahertz quantum cascade lasers

Here we demonstrate a Y coupled terahertz (THz) quantum cascade laser (QCL) system. The two THz QCLs working around 2.85 THz are driven by independent electrical pulsers. Total peak THz output power of the Y system, with both arms being driven synchronously, is found to be more than the linear sum of the peak powers from the individual arms; 10.4 mW compared with 9.6 mW (4.7 mW + 4.9 mW). Furthermore, we demonstrate that the emission spectra of this coupled system are significantly different to that of either arm alone, or to the linear combination of their individual spectra.Comment: 9 pages, 3 figure

Alien Registration- Ritchie, Augusta E. (Eastport, Washington County)

https://digitalmaine.com/alien_docs/1225/thumbnail.jp

Possible evidence of a spontaneous spin-polarization in mesoscopic 2D electron systems

We have experimentally studied the non-equilibrium transport in low-density clean 2D electron systems at mesoscopic length scales. At zero magnetic field (B), a double-peak structure in the non-linear conductance was observed close to the Fermi energy in the localized regime. From the behavior of these peaks at non-zero B, we could associate them to the opposite spin states of the system, indicating a spontaneous spin polarization at B = 0. Detailed temperature and disorder dependence of the structure shows that such a splitting is a ground state property of the low-density 2D systems.Comment: 7 pages, 5 figure