1,045 research outputs found

    Binary companions of nearby supernova remnants found with Gaia

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    © ESO, 2017. Aims. We search for runaway former companions of the progenitors of nearby Galactic core-collapse supernova remnants (SNRs) in the Tycho-Gaia astrometric solution (TGAS). Methods. We look for candidates among a sample of ten SNRs with distances 2kpc, taking astrometry and G magnitude from TGAS and B,V magnitudes from the AAVSO Photometric All-Sky Survey (APASS). A simple method of tracking back stars and finding the closest point to the SNR centre is shown to have several failings when ranking candidates. In particular, it neglects our expectation that massive stars preferentially have massive companions. We evolve a grid of binary stars to exploit these covariances in the distribution of runaway star properties in colour - magnitude - ejection velocity space. We construct an analytic model which predicts the properties of a runaway star, in which the model paramet ers are the location in the grid of progenitor binaries and the properties of the SNR. Using nested sampling we calculate the Bayesian evidence for each candidate to be the runaway and simultaneously constrain the properties of that runaway and of the SNR itself. Results. We identify four likely runaway companions of the Cygnus Loop (G074.0-08.5), HB 21 (G089.0+ 04.7), S147 (G180.0+ 01.7) and the Monoceros Loop (G205.5+ 00.5). HD 37424 has previously been suggested as the companion of S147, however the other three stars are new candidates. The favoured companion of HB 21 is the Be star BD+50 3188 whose emission-line features could be explained by pre-supernova mass transfer from the primary. There is a small probability that the 2M candidate runaway TYC 2688-1556-1 associated with the Cygnus Loop is a hypervelocity star. If the Monoceros Loop is related to the on-going star formation in the Mon OB2 association, the progenitor of the Monoceros Loop is required to be more massive than 40M which is in tension with the posterior for our candidate runaway star HD 261393.DPB is grateful to the Science and Technology Facilities Council (STFC) for providing Ph.D. funding. M.F. is supported by a Royal Society – Science Foundation Ireland University Research Fellowship. This work was partly supported by the European Union FP7 programme through ERC grant number 320360. RGI thanks the STFC for funding his Rutherford fellowship under grant ST/L003910/1 and Churchill College, Cambridge for his fellowship

    Future Cities: Asserting Public Governance

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    The smart city has become a main prism through which urban futures are viewed. With it comes the promise of big data technology enabling more resource-efficient urban systems and improved governance. Increasingly, however, this technocentric view is being challenged, at least rhetorically, by seeking to place people at the heart of smart city development. Yet, especially in the case of the UK, such development typically takes place within a governance context which marginalises established planning and decision processes, thus arguably weakening public accountability. Moreover, the norms of engagement change in that citizens are assigned more of an entrepreneurial role as co-producers of data-driven information. It becomes necessary, therefore, to reconsider as well as reinvigorate the place of the public in the future city. This article seeks to do so by making the case, on one hand, for strengthening institutional frameworks and, on the other, advancing a more active role for citizens to become involved in actualising and scrutinising future cities

    Ozone-depleting substances (ODSs) and related chemicals

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    The amended and adjusted Montreal Protocol continues to be successful at reducing emissions and atmospheric abundances of most controlled ozone-depleting substances (ODSs).Global Ozone Research and Monitoring Projec

    Core-collapse supernova progenitor constraints using the spatial distributions of massive stars in local galaxies

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    We study the spatial correlations between the Hα\alpha emission and different types of massive stars in two local galaxies, the Large Magellanic Cloud (LMC) and Messier 33. We compare these to correlations derived for core-collapse supernovae (CCSNe) in the literature to connect CCSNe of different types with the initial masses of their progenitors and to test the validity of progenitor mass estimates which use the pixel statistics method. We obtain samples of evolved massive stars in both galaxies from catalogues with good spatial coverage and/or completeness, and combine them with coordinates of main-sequence stars in the LMC from the SIMBAD database. We calculate the spatial correlation of stars of different classes and spectral types with Hα\alpha emission. We also investigate the effects of distance, noise and positional errors on the pixel statistics method. A higher correlation with Hα\alpha emission is found to correspond to a shorter stellar lifespan, and we conclude that the method can be used as an indicator of the ages, and therefore initial masses, of SN progenitors. We find that the spatial distributions of type II-P SNe and red supergiants of appropriate initial mass (≳\gtrsim9 M⊙M_{\odot}) are consistent with each other. We also find the distributions of type Ic SNe and WN stars with initial masses ≳\gtrsim20 M⊙M_{\odot} consistent, while supergiants with initial masses around 15 M⊙M_{\odot} are a better match for type IIb and II-L SNe. The type Ib distribution corresponds to the same stellar types as type II-P, which suggests an origin in interacting binaries. On the other hand, we find that luminous blue variable stars show a much stronger correlation with Hα\alpha emission than do type IIn SNe.ERC, STF

    A randomised control trial of low glycaemic index carbohydrate diet versus no dietary intervention in the prevention of recurrence of macrosomia

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    <p>Abstract</p> <p>Background</p> <p>Maternal weight and maternal weight gain during pregnancy exert a significant influence on infant birth weight and the incidence of macrosomia. Fetal macrosomia is associated with an increase in both adverse obstetric and neonatal outcome, and also confers a future risk of childhood obesity. Studies have shown that a low glycaemic diet is associated with lower birth weights, however these studies have been small and not randomised <abbrgrp><abbr bid="B1">1</abbr><abbr bid="B2">2</abbr></abbrgrp>. Fetal macrosomia recurs in a second pregnancy in one third of women, and maternal weight influences this recurrence risk <abbrgrp><abbr bid="B3">3</abbr></abbrgrp>.</p> <p>Methods/Design</p> <p>We propose a randomised control trial of low glycaemic index carbohydrate diet vs. no dietary intervention in the prevention of recurrence of fetal macrosomia.</p> <p>Secundigravid women whose first baby was macrosomic, defined as a birth weight greater than 4000 g will be recruited at their first antenatal visit.</p> <p>Patients will be randomised into two arms, a control arm which will receive no dietary intervention and a diet arm which will be commenced on a low glycaemic index diet.</p> <p>The primary outcome measure will be the mean birth weight centiles and ponderal indices in each group.</p> <p>Discussion</p> <p>Altering the source of maternal dietary carbohydrate may prove to be valuable in the management of pregnancies where there has been a history of fetal macrosomia. Fetal macrosomia recurs in a second pregnancy in one third of women. This randomised control trial will investigate whether or not a low glycaemic index diet can affect this recurrence risk.</p> <p>Current Controlled Trials Registration Number</p> <p>ISRCTN54392969</p

    Follicular fluid levels of vascular endothelial growth factor and early corpus luteum function during assisted reproductive technology cycles

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    BACKGROUND: The relation between vascular endothelial growth factor (VEGF) and early luteal function has rarely been proven in humans. The purpose of this study was to define the relation between follicular fluid concentrations of VEGF (FF VEGF) and early luteal function at the preimplantation stage during assisted reproductive technology (ART) cycles. METHODS: 71 women were divided into two groups, based on reproductive outcome: women who became pregnant after embryo transfer (ET) (n = 18, Group A) and non-pregnant women (n = 53, Group B). Serum progesterone (Se P) and inhibin A on ET day, and FF VEGF levels were measured in all women. Data were expressed as mean ± standard deviation. Statistical analysis was performed using Excel Office 98 for Student's t-test, linear regression test and chi-square test. A p value of < 0.05 was considered statistically significant. RESULTS: The groups were comparable for age, ovarian reserve, number and quality of the oocytes retrieved and of the embryos obtained and transferred. FF VEGF levels were increased (4235 ± 1433 vs 3432 ± 1231 pg/ml), while Se P and inhibin A levels were significantly reduced (83.1 ± 34.1 vs 112.0 ± 58.8 ng/ml and 397.4 ± 223 vs 533.5 ± 283 pg/ml, respectively) in the non-pregnant group and were negatively correlated with FF VEGF (r = -0.482, p < 0.05; r = -0.468, p < 0.05) only in pregnant women. CONCLUSION: Much has to be learned about the regulation and role of VEGF during the early luteal phase. We advance the hypothesis that the existence of a negative correlation between FF VEGF/Se P and FF VEGF/inhibin A in pregnant women might indicate the existence of a normal VEGF-mediated paracrine response when Se P and inhibin A levels are decreased. Excess production of FF VEGF and the absence of a correlation between FF VEGF/Se P and FF VEGF/inhibin A in non-pregnant women may be a paracrine reaction to immature luteal vasculature, resulting in luteal dysfunction

    Insights from Amphioxus into the Evolution of Vertebrate Cartilage

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    Central to the story of vertebrate evolution is the origin of the vertebrate head, a problem difficult to approach using paleontology and comparative morphology due to a lack of unambiguous intermediate forms. Embryologically, much of the vertebrate head is derived from two ectodermal tissues, the neural crest and cranial placodes. Recent work in protochordates suggests the first chordates possessed migratory neural tube cells with some features of neural crest cells. However, it is unclear how and when these cells acquired the ability to form cellular cartilage, a cell type unique to vertebrates. It has been variously proposed that the neural crest acquired chondrogenic ability by recruiting proto-chondrogenic gene programs deployed in the neural tube, pharynx, and notochord. To test these hypotheses we examined the expression of 11 amphioxus orthologs of genes involved in neural crest chondrogenesis. Consistent with cellular cartilage as a vertebrate novelty, we find that no single amphioxus tissue co-expresses all or most of these genes. However, most are variously co-expressed in mesodermal derivatives. Our results suggest that neural crest-derived cartilage evolved by serial cooption of genes which functioned primitively in mesoderm
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