1,409 research outputs found
El aprendizaje a través del movimiento en la enseñanza del alemán como lengua extranjera en la educación secundaria obligatoria. Un estudio de un caso práctico
Learning through movement is a teaching method in which physical movement is considered a central teaching
and learning tool. It is intended to support the learning process and lead to better information processing and
retention in learners of all ages. Despite this, however, physical activity is primarily used at the preschool and
primary levels. At the secondary level, where concentrated learning and grades are usually the primary focus,
movement activities often lose importance. This article presents findings from a school-based case study aimed
at investigating whether the use of learning through movement can lead to measurable performance gains in
adolescents.El aprendizaje a través del movimiento es un método de enseñanza en el que el movimiento físico se considera
una herramienta central de enseñanza y aprendizaje. Su objetivo es apoyar el proceso de aprendizaje y conducir a
un mejor procesamiento y retención de la información en alumnos de todas las edades. Sin embargo, la actividad
física se utiliza principalmente en la educación infantil y primaria. En el nivel secundario, donde el aprendizaje
concentrado y las calificaciones están en primer plano, las actividades de movimiento suelen perder importancia.
Este artículo presenta los resultados de un estudio de caso en un instituto de educación secundaria, cuyo objetivo
es investigar si el uso del aprendizaje a través del movimiento puede conducir a un aumento mensurable del
rendimiento entre los adolescentes
Artenliste der Zikaden Deutschlands, mit Angaben zu Nährpflanzen, Lebenszyklen und Verbreitung: (Hemiptera, Fulgoromorpha et Cicadomorpha)
Check list of the planthoppers and leafhoppers of Germany, with notes on food plants, life cycle and distribution (Hemiptera, Fulgoromorpha et Cicadomorpha). – An annotated check list of the planthoppers and leafhoppers of Germany is presented, with specifications of food plants, overwintering stage, annual generation numbers and overall distribution. The list includes 620 species, comprising 145 planthoppers and 475 leafhoppers. Five taxa, which were commonly considered as separate species were treated as morphs or varieties of other species. On the other hand, in a number of cases there is evidence that a taxon hitherto regarded as a single species may comprise at least two species. Two names were declared as new synonyms. Five species probably breed only irregularly, and at least four are neozoa originating form North America, Asia or the Mediterranean region
Ultra high performance liquid chromatographic-tandem mass spectrometric multi-analyte approach for target screening and quantification in human blood plasma : development, validation, and application
In the presented studies, the development of an UHPLC-MS/MS approach for fast target screening and quantification in plasma was described. This approach covered 136 analytes out of the drug classes of antidepressants, neuroleptics, benzodiazepines, beta-blockers, oral antidiabetics, and analytes to be determined in the context of brain death diagnosis. Further, it was possible to find one chromatographic system with the same column and mobile phase compositions to separate almost all these analytes sufficiently. A fast and simple liquid-liquid extraction for all these analytes was developed. In addition, the presented studies showed that ion suppression and enhancement tests were essential, particularly for the selection of internal standards for UHPLC-MS/MS multi-analyte procedures and for combining co-eluting analytes during method validation. Furthermore, this approach was fully validated for the most important drug classes of antidepressants, neuroleptics, and benzodiazepines. This approach was valid for 28 antidepressants, 24 neuroleptics, and 21 benzodiazepines. In addition, the applicability was shown successfully using authentic human blood samples and external quality control samples. The cost and time saving one-point calibration was shown to be sufficient for more than half of the analytes.Im Rahmen dieser Dissertation wurde die Entwicklung einer UHPLC-MS//MS Methode für schnelles Target-Screening und Quantifizierung im Plasma beschrieben. Die Methode umfasste 136 Arzneistoffe aus den Stoffgruppen der Antidepressiva, Neuroleptika, Benzodiazepine, Betablocker, orale Antidiabetika und Arzneistoffe, die im Rahmen der Hirntoddiagnostik untersucht werden müssen. Weiterhin war es möglich, ein chromatographisches System, unter Verwendung derselben Säule und Fließmittelzusammensetzung, für die Trennung aller Arzneistoffe zu finden. Eine schnelle und einfache Flüssig-Flüssig-Extraktion wurde für alle Arzneistoffe entwickelt. Die Notwendigkeit von Untersuchungen zur Ionenunterdrückung und Ionenerhöhung konnte ebenfalls in dieser Arbeit belegt werden. Diese Untersuchungen waren für die Wahl des internen Standards für LC-MS/MS Methoden und für die Zusammensetzung von co-chromatographierenden Stoffen wichtig. Weiterhin wurde diese Methode für die wichtigsten Stoffgruppen nämlich die Antidepressiva, Neuroleptika und Benzodiazepine voll validiert. Es konnte gezeigt werden, dass die Methode für 28 Antidepressiva, 24 Neuroleptika und 21 Benzodiazepine valide war. Die Anwendbarkeit wurde mittels humaner authentischer Plasmaproben und mittels externen Qualitätskontrollproben gezeigt. Die kosten- und zeitsparende Ein-Punkt-Kalibrierung erwies sich für über die Hälfte der Arzneistoffe als akzeptabel
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