14 research outputs found
Biomodulation effects of LED and therapeutic ultrasound combined with semipermeable dressing in the repair process of cutaneous lesions in rats
Mental health problems among medical students in Brazil: a systematic review and meta-analysis
The mitochondrial toxin 3-nitropropionic acid aggravates reserpine-induced oral dyskinesia in rats
The effects of a previous long-term administration of the mitochondrial toxin 3-nitropropionic acid were studied on an animal model of tardive dyskinesia, i.e., die frequency of spontaneous tongue protrusions in rats repeatedly treated with reserpine. 3-Nitropropionic acid (10 or 15 mg/kg ip, every other day for 17 days) potentiated the increase in tongue-protrusion frequency induced by reserpine (1 mg/kg, sc, every other day for 3 days) but did not modify reserpine-induced increase in immobility duration and decrease in locomotion frequency. These results support the notion that neurotoxic events are associated with the development of tardive dyskinesia. (C) 2001 Elsevier Science Inc. All rights reserved.Dept Farmacol, BR-04023970 São Paulo, BrazilUniversidade Federal de São Paulo, Dept Pediat, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Pediat, São Paulo, BrazilWeb of Scienc