Antimitotic Effect of Ethanol Fraction of Hibiscus mutabilis Leaf and Flowers

Hibiscus mutabilis is reported for bioactive constituent. Ethanol fraction of Hibiscus mutabilis leaf and flower were studied for antimitotic activity. Allium cepa roots were used to evaluate cytotoxicity effect of the extracts. Ethanol soluble part of leaf and flower showed inhibitory effect on root length and root number growth on third day of incubation which is comparable with paracetamol as standard drug used. Reduction in number of dividing cells in the root meristem due to ethanolic fraction of leaf reveals antimitotic activity which is dose dependant. The constituents present in ethanolic extract may be responsible for cytoskeleton or tubulin polymerization or degradation that demonstrates antimitotic behavior

Multi-Language based Android Application for Motor Control

some wise individual once aforementioned that system could be a system wherever we will finish off the machine whenever we'd like. That’s the distinction between controlled and uncontrolled system. Our project is regarding create this system economical and dynamic. Because the name instructed the automated management is for dominant the motor from remote place, look over its operational conditions; get feedback from the motor itself. Our target is to manage the motor from distant place by mobile DTMF tone and conjointly get feedback by SMS whereas it's in ON or OFF condition. We tend to conjointly make sure the safe operation of the motor by police investigation the voltage of the supply and guarantee feedback from system whereas it's over or below voltage. Once more we tend to conjointly get these feedbacks by SMS additionally. GSM network is all over in our country that’s why we decide GSM network to control our motor conjointly transferring feedback data through it. We tend to conjointly use GSM network as a result of if we tend to use it then we tend to don’t have to be compelled to establish further instrumentation for networking. To transmit feedback signals we tend to use GSM electronic equipment at the motor finish conjointly generate management signal by mobile DTMF as a result of it's terribly simple to get DTMF by mobile station and send feedback SMS by electronic equipment additionally. In industrial sector we tend to hope our project is become handy and value effective to control motor and provides its protection

STUDIES ON BIOAVAILABILITY ENHANCEMENT OF CURCUMIN

Objective: The objective of the present work was to improve aqueous solubility and in vivo bioavailability of curcumin and structural analogues of curcumin such as potassium, calcium, magnesium salts and nitro derivative. Methods: Structural analogues of curcumin were prepared by reaction of curcumin with potassium chloride, magnesium chloride hexahydrate and calcium chloride dihydrate in a suitable solvent. The nitro derivative synthesized by treating curcumin with sulphuric acid and nitric acid. The prepared analogues were evaluated for melting behavior, solubility, UV spectrophotometry, partition coefficient, moisture content, cellular uptake, FTIR analysis, antimicrobial activity and in vivo bioavailability in the rat. Results: Chemical modification of curcumin increased the saturation solubility to 11.6, 16.5, 21.5, 28.0 µg/ml in calcium salt, magnesium salt, potassium salt and nitro derivative respectively, against 8.6 µg/ml of curcumin. The analogues were chemically stable as curcumin analyzed by FTIR spectrophotometry. Increased cellular uptake, as well as enhanced antimicrobial activity, was demonstrated by modified curcumin analogues. Moreover, significant improvement in plasma levels was estimated with nitro derivative. Conclusion: The present work recommends that nitration of curcumin improves aqueous solubility which may improve absorption and in vivo bioavailability

Celastrus paniculatus and memantine prevent alcohol dependence and improve decision making in alcohol dependent C57BL6 mice

Background: Alcohol use disorder poses a huge burden with only a handful of approved drugs. AUD is associated with impaired decision-making that leads to compulsive drinking despite negative consequences. A drug that decreases alcohol consumption as well as improves decision-making may thus prove more useful. This study was planned to evaluate the effect of two drugs, Celastrus paniculatus and memantine on alcohol preference and decision impairment in alcohol-dependent mice. Methods: In part 1, the effect of both the study drugs on alcohol consumption was studied using intermittent access model in 70 male C57BL6 mice. In part 2, effect of drugs on decision making was studied using the rodent version of Iowa gambling task. Mice were divided in seven study groups: Group 1-3: Celastrus paniculatus (140, 280, and 560 mg/kg), Group 4: memantine (25 mg/kg), Group 5: vehicle control 1 (Milk), Group 6: vehicle control 2 (normal saline) and Group 7: naltrexone(1mg/kg). Results: Percentage alcohol preference was lower in test groups i.e., Celastrus paniculatus at medium (40.90±15.18%) and high doses (31.79±7.46%) vs. milk (82.74±8.53%; p<0.05); and in memantine group (36.28±10.99%) vs. normal saline (83.27±5.51%; p<0.05). The results were not significantly different to Naltrexone (19.70±6.90%). Percentage preference to disadvantageous arms was also lower in Celastrus paniculatus, at medium (50.52±1.92%) and high doses (48.11±2.43%) compared to milk (54.47±2.73%; p<0.05) and memantine (47.45±1.67%) compared to normal saline (54.00±2.73%; p<0.05), indicating better decision-making ability in the test groups. The findings were comparable to Naltrexone group (45.43±2.52%). Conclusions: These results indicate that Celastrus paniculatus and memantine reduce alcohol consumption and improve decision making in alcohol-dependent mice

Temperature, RF Field, and Frequency Dependence Performance Evaluation of Superconducting Niobium Half-Wave Coaxial Cavity

Recent advancement in superconducting radio frequency cavity processing techniques, with diffusion of impurities within the RF penetration depth, resulted in high quality factor with increase in quality factor with increasing accelerating gradient. The increase in quality factor is the result of a decrease in the surface resistance as a result of nonmagnetic impurities doping and change in electronic density of states. The fundamental understanding of the dependence of surface resistance on frequency and surface preparation is still an active area of research. Here, we present the result of RF measurements of the TEM modes in a coaxial half-wave niobium cavity resonating at frequencies between 0.3 - 1.3 GHz. The temperature dependence of the surface resistance was measured between 4.2 K and 1.6 K. The field dependence of the surface resistance was measured at 2.0 K. The baseline measurements were made after standard surface preparation by buffered chemical polishing

LAN Monitoring Using Android Phone

ABSTRACT: Now a day's android phones are used for the various applications. We can use android phone for monitor and control the network. It is to control the network when network admin is in admin office but it is difficult to control the network from outside the office. It is integrated software solution that allows a network admin to remotely monitor his LAN network by his Android phone with GUI. The main purpose of this application is to provide all the important details of the network to the admin on their android phone with the help of GPRS or Wi-Fi. We are using data connectivity or Wi-Fi to connect the mobile phone to LAN server. And we also are using password encryption for authentication in phone

New records of Conidae (Mollusca, Gastropoda) from Andhra Pradesh, east coast of India

641-647A benthic investigation from the coastal corridor of Andhra Pradesh revealed 17 species of cone snails. Of these, seven species, namely Conasprella aculeiformis Reeve, C. coromandelica (E. A. Smith), Conus amadis (Gmelin), C. caracteristicus (Fischer von Waldheim), C. coronatus (Gmelin), C. monile Hwass in Bruguiere, and C. sulcatus Hwass in Bruguière are recorded for the first time from the coastal waters of Andhra Pradesh. The present findings of Conus from Andhra Pradesh coast are indicative of the species extended distribution to the northeast coast along the Bay of Bengal. Additionally, the live specimens collected could be of resource value for species description and historical analyses

New records of Conidae (Mollusca, Gastropoda) from Andhra Pradesh, east coast of India

A benthic investigation from the coastal corridor of Andhra Pradesh revealed 17 species of cone snails. Of these, seven species, namely Conasprella aculeiformis Reeve, C. coromandelica (E. A. Smith), Conus amadis (Gmelin), C. caracteristicus (Fischer von Waldheim), C. coronatus (Gmelin), C. monile Hwass in Bruguiere, and C. sulcatus Hwass in Bruguière are recorded for the first time from the coastal waters of Andhra Pradesh. The present findings of Conus from Andhra Pradesh coast are indicative of the species extended distribution to the northeast coast along the Bay of Bengal. Additionally, the live specimens collected could be of resource value for species description and historical analyses

First record of Veneridae clam Protapes ziczac (Linnaeus, 1758) from east coast of India, Andhra Pradesh

A venerid bivalve Protapes ziczac (Linnaeus, 1758) from benthic collections is reported for the first time from the coastal waters of Andhra Pradesh, east coast of India. The findings of this study indicate the extended distributional range of the species, until now documented from the west coast of India