19 research outputs found

    Search for Gravitational Waves Associated with Gamma-Ray Bursts Detected by Fermi and Swift during the LIGO-Virgo Run O3b

    Get PDF
    We search for gravitational-wave signals associated with gamma-ray bursts (GRBs) detected by the Fermi and Swift satellites during the second half of the third observing run of Advanced LIGO and Advanced Virgo (2019 November 1 15:00 UTC-2020 March 27 17:00 UTC). We conduct two independent searches: A generic gravitational-wave transients search to analyze 86 GRBs and an analysis to target binary mergers with at least one neutron star as short GRB progenitors for 17 events. We find no significant evidence for gravitational-wave signals associated with any of these GRBs. A weighted binomial test of the combined results finds no evidence for subthreshold gravitational-wave signals associated with this GRB ensemble either. We use several source types and signal morphologies during the searches, resulting in lower bounds on the estimated distance to each GRB. Finally, we constrain the population of low-luminosity short GRBs using results from the first to the third observing runs of Advanced LIGO and Advanced Virgo. The resulting population is in accordance with the local binary neutron star merger rate. © 2022. The Author(s). Published by the American Astronomical Society

    The actin cytoskeleton in ageing and apoptosis.

    No full text
    Regulated cell death, or apoptosis, has evolved to fulfil a myriad of functions amongst multicellular organisms. It is now apparent that programmed cell death occurs in unicellular organisms such as yeast. In yeast, as in higher eukaryotes, the actin cytoskeleton is an essential component of a number of cellular activities, and many of the regulatory proteins involved are highly conserved. Recent evidence from diverse eukaryotic systems suggests that the actin cytoskeleton has a role in regulating apoptosis via interactions with the mitochondria. This interaction also appears to have a significant impact on the management of oxidative stress and so cellular ageing. In this mini-review we summarise some of the work, which suggests that actin is a key regulator of apoptosis and ageing in eukaryotic cells

    Alzheimer’s Disease Targeted Nano-Based Drug Delivery Systems

    No full text

    Searches for continuous gravitational waves from young supernova remnants in the early third observing run of Advanced LIGO and Virgo

    No full text
    We present results of three wide-band directed searches for continuous gravitational waves from 15 young supernova remnants in the first half of the third Advanced LIGO and Virgo observing run. We use three search pipelines with distinct signal models and methods of identifying noise artifacts. Without ephemerides of these sources, the searches are conducted over a frequency band spanning from 10~Hz to 2~kHz. We find no evidence of continuous gravitational radiation from these sources. We set upper limits on the intrinsic signal strain at 95% confidence level in sample sub-bands, estimate the sensitivity in the full band, and derive the corresponding constraints on the fiducial neutron star ellipticity and rr-mode amplitude. The best 95% confidence constraints placed on the signal strain are 7.7×10267.7\times 10^{-26} and 7.8×10267.8\times 10^{-26} near 200~Hz for the supernova remnants G39.2--0.3 and G65.7+1.2, respectively. The most stringent constraints on the ellipticity and rr-mode amplitude reach 107\lesssim 10^{-7} and 105 \lesssim 10^{-5}, respectively, at frequencies above 400\sim 400~Hz for the closest supernova remnant G266.2--1.2/Vela Jr

    Search for Gravitational Waves Associated with Fast Radio Bursts Detected by CHIME/FRB During the LIGO--Virgo Observing Run O3a

    No full text
    We search for gravitational-wave transients associated with fast radio bursts (FRBs) detected by the Canadian Hydrogen Intensity Mapping Experiment Fast Radio Burst Project (CHIME/FRB), during the first part of the third observing run of Advanced LIGO and Advanced Virgo (1 April 2019 15:00 UTC-1 Oct 2019 15:00 UTC). Triggers from 22 FRBs were analyzed with a search that targets compact binary coalescences with at least one neutron star component. A targeted search for generic gravitational-wave transients was conducted on 40 FRBs. We find no significant evidence for a gravitational-wave association in either search. Given the large uncertainties in the distances of the FRBs inferred from the dispersion measures in our sample, however, this does not conclusively exclude any progenitor models that include emission of a gravitational wave of the types searched for from any of these FRB events. We report 90%90\% confidence lower bounds on the distance to each FRB for a range of gravitational-wave progenitor models. By combining the inferred maximum distance information for each FRB with the sensitivity of the gravitational-wave searches, we set upper limits on the energy emitted through gravitational waves for a range of emission scenarios. We find values of order 105110^{51}-105710^{57} erg for a range of different emission models with central gravitational wave frequencies in the range 70-3560 Hz. Finally, we also found no significant coincident detection of gravitational waves with the repeater, FRB 20200120E, which is the closest known extragalactic FRB
    corecore