Path enumeration program (ENUMPTH) for physical protection effectiveness evaluation

Descriptions are presented of the structure and of ENUMPTH, a program for enumerating paths which an adversary might follow in attempting defeat of physical protection systems. The paths are evaluated in terms of the probability of detecting and then interrupting the adversary as the paths are traversed. The program is intended to be practical in orientation, selecting all paths which meet some specified minimum criteria. The nature of the physical protection issue suggests that all such paths may be of equal interest to analysts who are concerned with a total facility. An example is given to demonstrate the program's applicability to practical problems

Absence of a dose-rate effect in the transformation of C3H 10T1/2 cells by α-particles

The findings of Hill et al. (1984) on the greatly enhanced transformation frequencies at very low dose rates of fission neutrons induced us to perform an analogous study with -particles at comparable dose rates. Transformation frequencies were determined with γ-rays at high dose rate (0·5 Gy/min), and with -particles at high (0·2 Gy/min) and at low dose rates (0·83-2·5 mGy/min) in the C3H 10T1/2 cell system. α-particles were substantially more effective than γ-rays, both for cell inactivation and for neoplastic transformation at high and low dose rates. The relative biological effectiveness (RBE) for cell inactivation and for neoplastic transformation was of similar magnitude, and ranged from about 3 at an -particle dose of 2 Gy to values of the order of 10 at 0·25 Gy. In contrast to the experiments of Hill et al. (1984) with fission neutrons, no increased transformation frequencies were observed when the -particle dose was protracted over several hours

Climate Change in Queensland's Grazing Lands. I. Approaches and Climatic Trends

Climate change is an important global issue but is yet to be recognised as such by many rangelands users. This paper reviews some of the uncertainties relating to pre-instrumental and future climate change and documents current trends and fluctuations in climate of Queensland's grazing lands. Analysis of daily climate surfaces for Queensland's pastoral/cropping zone shows high variability in annual rainfall which is influenced by the El NiHo-Southern Oscillation (ENSO) phenomenon. This relationship, when examined using moving windows, has changed during this century with the 1930-40s being a period of low correlation. Minimum temperatures taken from the climate surfaces also changed, showing a significant (P<0.01) increase over time especially in May. Over the 40 years since 1957, annual minimum temperatures have increased by l.0°C for the pastoral/cropping zone and coastal sub-zone, winter minimum temperatures by 1.2°C for the pastoral/cropping zone (1.3°C for the coastal sub-zone), summer minimum temperatures by 0.7°C for the pastoral/cropping zone and coastal sub-zone, and May minimum temperatures by 2.8°C for the pastoral/cropping zone (3.0°C for the coastal sub-zone). Consistent significant trends in vapour pressure (increasing, P<0.001) and solar radiation (decreasing, P<0.05) also occurred in May. The mechanisms for the identified climate trends and unusual behaviour of ENS0 are the subject of speculation with attribution of causes to natural variability or the enhanced greenhouse effect being unresolved. Continued monitoring of these trends and fluctuations will be important for the future management of Queensland's grazing lands with this analysis highlighting the need for discrimination of trends from natural variability. In terms of grazing management and degradation processes, this work also highlights that general changes in climate averages may disguise important variation at yearly and decadal time scales

Herbicide-use trends in prairie canola production systems

Non-Peer Reviewe

Gaussian quantum marginal problem

The quantum marginal problem asks what local spectra are consistent with a given spectrum of a joint state of a composite quantum system. This setting, also referred to as the question of the compatibility of local spectra, has several applications in quantum information theory. Here, we introduce the analogue of this statement for Gaussian states for any number of modes, and solve it in generality, for pure and mixed states, both concerning necessary and sufficient conditions. Formally, our result can be viewed as an analogue of the Sing-Thompson Theorem (respectively Horn's Lemma), characterizing the relationship between main diagonal elements and singular values of a complex matrix: We find necessary and sufficient conditions for vectors (d1, ..., dn) and (c1, ..., cn) to be the symplectic eigenvalues and symplectic main diagonal elements of a strictly positive real matrix, respectively. More physically speaking, this result determines what local temperatures or entropies are consistent with a pure or mixed Gaussian state of several modes. We find that this result implies a solution to the problem of sharing of entanglement in pure Gaussian states and allows for estimating the global entropy of non-Gaussian states based on local measurements. Implications to the actual preparation of multi-mode continuous-variable entangled states are discussed. We compare the findings with the marginal problem for qubits, the solution of which for pure states has a strikingly similar and in fact simple form.Comment: 18 pages, 1 figure, material added, references updated, except from figure identical with version to appear in Commun. Math. Phy

Prolonged enoxaparin therapy compared with standard-of-care antithrombotic therapy in opiate-treated patients undergoing primary percutaneous coronary intervention

A novel enoxaparin regimen consisting of intra-arterial bolus (0.75 mg/kg) followed by intravenous infusion (0.75 mg/kg/6 hours) has been developed as a possible solution to the delayed absorption of oral P2Y12 inhibitors in opiate-treated ST-elevation myocardial infarction (STEMI) patients undergoing primary angioplasty. We aimed to study the feasibility of this regimen as an alternative to standard-of-care treatment (SOC) with unfractionated heparin ± glycoprotein IIb/IIIa antagonist (GPI). One hundred opiate-treated patients presenting with STEMI and accepted for primary angioplasty were randomized (1:1) to either enoxaparin or SOC. Fifty patients were allocated enoxaparin (median age 61, 40% females) and 49 allocated SOC (median age 62, 22% females). One developed stroke before angiography and was withdrawn. One SOC patient had a gastrointestinal bleed resulting in 1 g drop in hemoglobin and early cessation of GPI infusion. Two enoxaparin patients had transient minor bleeding: one transient gingival bleed and one episode of coffee ground vomit with no hemoglobin drop or hemodynamic instability. Two SOC and no enoxaparin group patients had acute stent thrombosis. These preliminary data support further study of this novel 6-hour enoxaparin regimen in opiate-treated PPCI patients

Finite covers of random 3-manifolds

A 3-manifold is Haken if it contains a topologically essential surface. The Virtual Haken Conjecture posits that every irreducible 3-manifold with infinite fundamental group has a finite cover which is Haken. In this paper, we study random 3-manifolds and their finite covers in an attempt to shed light on this difficult question. In particular, we consider random Heegaard splittings by gluing two handlebodies by the result of a random walk in the mapping class group of a surface. For this model of random 3-manifold, we are able to compute the probabilities that the resulting manifolds have finite covers of particular kinds. Our results contrast with the analogous probabilities for groups coming from random balanced presentations, giving quantitative theorems to the effect that 3-manifold groups have many more finite quotients than random groups. The next natural question is whether these covers have positive betti number. For abelian covers of a fixed type over 3-manifolds of Heegaard genus 2, we show that the probability of positive betti number is 0. In fact, many of these questions boil down to questions about the mapping class group. We are lead to consider the action of mapping class group of a surface S on the set of quotients pi_1(S) -> Q. If Q is a simple group, we show that if the genus of S is large, then this action is very mixing. In particular, the action factors through the alternating group of each orbit. This is analogous to Goldman's theorem that the action of the mapping class group on the SU(2) character variety is ergodic.Comment: 60 pages; v2: minor changes. v3: minor changes; final versio