Aspects of resistance in deepwater rice to the stem nematode Ditylenchus angustus

Une technique utilisant les plants de riz a été mise au point pour cribler la résistance du riz flottant à #Ditylenchus angustus$. Cette technique copie l'infestation naturelle à partir de l'eau et permet une infestation de 100$ est rapide sur les cvs sensibles (la durée du cycle est de 10 à 20 jours, à 30°C). L'expression des symptômes et la multiplication du nématode ont été étudiées sur une série de cultivars et lignées de riz flottant, tant sensibles que résistants. La résistance est en partie conférée par une réaction nécrotique rapide de l'hôte lors de la prise de nourriture du nématode. Cette réaction est présente chez quelques lignées (CNL 319, Bazail 65, Rayada 16-02, Rayada 16-03, Rayad 16-06 à 16-09) qui se sont montrées en champ résistantes en divers endroits et au cours du temps. Une telle réaction est qualitativement différente de celle, bien connue, montrée par les plantes sensibles, et peut ainsi fournir une base en vue de la sélection génotypique. La relation entre profondeur de l'eau et taille des plants de riz est d'une importance cruciale pour le déclenchement de l'infestation et le développement des symptômes. #D. angustus$ pénètre dans les plants d'abord au niveau de la surface de l'eau, aussi une submersion des gaînes des feuilles retardera-t-elle l'infestation. Les symptômes se développent plus rapidement si, durant l'infestation, le niveau de l'eau est voisin de ou très peu inférieur à celui du collet situé au sommet de la gaîne foliaire. L'expression des symptômes, et par conséquent les dégâts précoces, sont ralentis en abaissant le niveau de l'eau. (Résumé d'auteur

An idealized numerical study of tropical cyclogenesis and evolution at the Equator

Tropical cyclone formation and evolution at, or near, the Equator is explored using idealized three‐dimensional model simulations, starting from a prescribed, initial, weak counterclockwise rotating vortex in an otherwise quiescent, nonrotating environment. Three simulations are carried out in which the maximum tangential wind speed (5 m surn:x-wiley:qj:media:qj3701:qj3701-math-0001) is specified at an initial radius of 50, 100, or 150 km. After a period of gestation lasting between 30 and 60 hr, the vortices intensify rapidly, the evolution being similar to that for vortices away from the Equator. In particular, the larger the initial vortex size, the longer the gestation period, the larger the maximum intensity attained, and the longer the vortex lifetime. Beyond a few days, the vortices decay as the cyclonic vorticity source provided by the initial vortex is depleted and negative vorticity surrounding the vortex core is drawn inwards by the convectively driven overturning circulation. In these negative vorticity regions, the flow is inertially/centrifugally unstable. The vortex evolution during the mature and decay phases differs from that in simulations away from the Equator, where inertially unstable regions are much more limited in area. Vortex decay in the simulations appears to be related intimately to the development of inertial instability, which is accompanied by an outward‐propagating band of deep convection. The degree to which this band of deep convection is realistic is unknown

Clinical and laboratory variability in a cohort of patients diagnosed with type 1 VWD in the United States

Von Willebrand disease (VWD) is the most common inherited bleeding disorder, and type 1 VWD is the most common VWD variant. Despite its frequency, diagnosis of type 1 VWD remains the subject of much debate. In order to study the spectrum of type 1 VWD in the United States, the Zimmerman Program enrolled 482 subjects with a previous diagnosis of type 1 VWD without stringent laboratory diagnostic criteria. VWF laboratory testing and full length VWF gene sequencing were performed for all index cases and healthy control subjects in a central laboratory. Bleeding phenotype was characterized using the ISTH Bleeding Assessment Tool. At study entry, 64% of subjects had VWF:Ag or VWF:RCo below the lower limit of normal, while 36% had normal VWF levels. VWF sequence variations were most frequent in subjects with VWF:Ag < 30 IU/dL (82%) while subjects with type 1 VWD and VWF:Ag ≥ 30 IU/dL had an intermediate frequency of variants (44%). Subjects whose VWF testing was normal at study entry had a similar rate of sequence variations as the healthy controls at 14% of subjects. All subjects with severe type 1 VWD and VWF:Ag ≤ 5 IU/dL had an abnormal bleeding score, but otherwise bleeding score did not correlate with VWF:Ag level. Subjects with a historical diagnosis of type 1 VWD had similar rates of abnormal bleeding scores compared to subjects with low VWF levels at study entry. Type 1 VWD in the United States is highly variable, and bleeding symptoms are frequent in this population

Cross-talk between GABAergic postsynapse and microglia regulate synapse loss after brain ischemia.

Microglia interact with neurons to facilitate synapse plasticity; however, signal(s) contributing to microglia activation for synapse elimination in pathology are not fully understood. Here, using in vitro organotypic hippocampal slice cultures and transient middle cerebral artery occlusion (MCAO) in genetically engineered mice in vivo, we report that at 24 hours after ischemia, microglia release brain-derived neurotrophic factor (BDNF) to downregulate glutamatergic and GABAergic synapses within the peri-infarct area. Analysis of the cornu ammonis 1 (CA1) in vitro shows that proBDNF and mBDNF downregulate glutamatergic dendritic spines and gephyrin scaffold stability through p75 neurotrophin receptor (p75 &lt;sup&gt;NTR&lt;/sup&gt; ) and tropomyosin receptor kinase B (TrkB) receptors, respectively. After MCAO, we report that in the peri-infarct area and in the corresponding contralateral hemisphere, similar neuroplasticity occurs through microglia activation and gephyrin phosphorylation at serine-268 and serine-270 in vivo. Targeted deletion of the Bdnf gene in microglia or GphnS268A/S270A (phospho-null) point mutations protects against ischemic brain damage, neuroinflammation, and synapse downregulation after MCAO

An Automated Algorithm to Distinguish and Characterize Solar Flares and Associated Sequential Chromospheric Brightenings

We present a new automated algorithm to identify, track, and characterize small-scale brightening associated with solar eruptive phenomena observed in H{\alpha}. The temporal spatially-localized changes in chromospheric intensities can be separated into two categories: flare ribbons and sequential chromospheric brightenings (SCBs). Within each category of brightening we determine the smallest resolvable locus of pixels, a kernel, and track the temporal evolution of the position and intensity of each kernel. This tracking is accomplished by isolating the eruptive features, identifying kernels, and linking detections between frames into trajectories of kernels. We fully characterize the evolving intensity and morphology of the flare ribbons by observing the tracked flare kernels in aggregate. With the location of SCB and flare kernels identified, they can easily be overlaid on top of complementary data sets to extract Doppler velocities and magnetic field intensities underlying the kernels. This algorithm is adaptable to any dataset to identify and track solar features.Comment: 22 pages, 9 figure

Topological Defects and CMB anisotropies : Are the predictions reliable ?

We consider a network of topological defects which can partly decay into neutrinos, photons, baryons, or Cold Dark Matter. We find that the degree-scale amplitude of the cosmic microwave background (CMB) anisotropies as well as the shape of the matter power spectrum can be considerably modified when such a decay is taken into account. We conclude that present predictions concerning structure formation by defects might be unreliable.Comment: 14 pages, accepted for publication in PR

Field Measurements of Terrestrial and Martian Dust Devils

Surface-based measurements of terrestrial and martian dust devils/convective vortices provided from mobile and stationary platforms are discussed. Imaging of terrestrial dust devils has quantified their rotational and vertical wind speeds, translation speeds, dimensions, dust load, and frequency of occurrence. Imaging of martian dust devils has provided translation speeds and constraints on dimensions, but only limited constraints on vertical motion within a vortex. The longer mission durations on Mars afforded by long operating robotic landers and rovers have provided statistical quantification of vortex occurrence (time-of-sol, and recently seasonal) that has until recently not been a primary outcome of more temporally limited terrestrial dust devil measurement campaigns. Terrestrial measurement campaigns have included a more extensive range of measured vortex parameters (pressure, wind, morphology, etc.) than have martian opportunities, with electric field and direct measure of dust abundance not yet obtained on Mars. No martian robotic mission has yet provided contemporaneous high frequency wind and pressure measurements. Comparison of measured terrestrial and martian dust devil characteristics suggests that martian dust devils are larger and possess faster maximum rotational wind speeds, that the absolute magnitude of the pressure deficit within a terrestrial dust devil is an order of magnitude greater than a martian dust devil, and that the time-of-day variation in vortex frequency is similar. Recent terrestrial investigations have demonstrated the presence of diagnostic dust devil signals within seismic and infrasound measurements; an upcoming Mars robotic mission will obtain similar measurement types