870 research outputs found

    A Political Economy of Privatization Contracts : The Case of Water and Sanitation in Ghana and Argentina

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    This document is the Accepted Manuscript version of the following article: Hulya Dagdeviren, Simon A. Robertson, 'A Political Economy of Privatization Contracts: The Case of Water and Sanitation in Ghana and Argentina', Competition & Change, Vol. 18 (2): 150-163, April 2014. The final, published version is available online at DOI: https://doi.org/10.1179/1024529414Z.00000000053. Published by SAGE.In general, the process and outcomes of privatization have been studied from the point of view of efficiency. In this article, we consider issues in the course of contract design, implementation, management and enforcement in privatized public services and utilities. The study is based on two case studies, involving several water concessions in Argentina and a management contract in the urban water sector in Ghana. Three key arguments are presented on the basis of these case studies. The first is that an individualistic analytical framework is often utilized by the mainstream economic perspectives, but these are inadequate for a comparative assessment of private versus public provision in public services where there are distinct collective or group interests and hence a wider socio-economic context and representation of different interests becomes highly important. Instead, the article proposes a political economy perspective, which pays due attention to distributional issues, group interests, ideology of states and power relations for the assessment of privatization contracts. Second, the administrative capacity of states and their resources play a key role for the outcomes of privatization. Finally, while some contractual issues could be resolved through resourcing and experience over time, others are inherent to the contractual relations with little prospect of remedy.Peer reviewe

    Inequality of happiness in nations

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    The first comparison of happiness in nations took place in 1948 and involved 9 countries (Buchanan, 1953). A second comparative study in 1960 covered 14 nations (Cantril 1965) and this was followed by a global survey in 1975 carried out by Gallup (1976), in which happiness in all parts of the world was assessed. Today we have comparable data on happiness in 90 nations and for a dozen nations we also have time series of 40 to 25 years (Veenhoven 2004). These data provide the fuel for a rising number of publications on happiness in nations. Currently, the Bibliography of Happiness counts some 400 entries on this subject, 20% of which have been published over the last 5 years. To date, all the studies have been focused on the level of happiness in nations, that is, on how happy citizens are in a country. In this special issue we look at the same data from a different perspective and focus on difference in happiness in nations, that is, on the degree of divergence with regard to happiness found among citizens in a particular country

    Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway

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    BACKGROUND: Prostaglandin E(2) (PGE(2)) has been shown to modulate angiogenesis and tumour progression via the E-series prostanoid-2 (EP2) receptor. Endometrial adenocarcinomas may be exposed to endogenous PGE(2) and exogenous PGE(2), present at high concentration in seminal plasma. METHODS: This study investigated fibroblast growth factor 2 (FGF2) mRNA expression and cell signalling in response to seminal plasma or PGE(2), using an endometrial adenocarcinoma (Ishikawa) cell line stably expressing the EP2 receptor (EP2 sense cells) and endometrial adenocarcinoma explants. RESULTS: Seminal plasma and PGE(2) induced a significant up-regulation of FGF2 expression in EP2 sense but not parental untransfected Ishikawa (wild-type) cells (P < 0.05). These effects were inhibited by co-treatment with EP2 receptor antagonist or inhibitors of protein kinase A, c-Src, epidermal growth factor receptor (EGFR) kinase or extracellular signal-regulated kinase (ERK) signalling. The treatment of EP2 sense cells with seminal plasma induced cAMP accumulation and phosphorylation of c-Src, EGFR kinase and ERK via the EP2 receptor. Finally, seminal plasma and PGE(2) significantly increased FGF2 mRNA expression in endometrial adenocarcinoma tissue explants via the EP2 receptor (P < 0.05). CONCLUSIONS: Seminal plasma and PGE(2) can similarly activate FGF2 expression and EP2 receptor signalling in endometrial adenocarcinoma cells. These data highlight the potential for seminal plasma exposure to facilitate tumorigenesis–angiogenesis in endometrial adenocarcinomas in vivo

    Small BGK waves and nonlinear Landau damping

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    Consider 1D Vlasov-poisson system with a fixed ion background and periodic condition on the space variable. First, we show that for general homogeneous equilibria, within any small neighborhood in the Sobolev space W^{s,p} (p>1,s<1+(1/p)) of the steady distribution function, there exist nontrivial travelling wave solutions (BGK waves) with arbitrary minimal period and traveling speed. This implies that nonlinear Landau damping is not true in W^{s,p}(s<1+(1/p)) space for any homogeneous equilibria and any spatial period. Indeed, in W^{s,p} (s<1+(1/p)) neighborhood of any homogeneous state, the long time dynamics is very rich, including travelling BGK waves, unstable homogeneous states and their possible invariant manifolds. Second, it is shown that for homogeneous equilibria satisfying Penrose's linear stability condition, there exist no nontrivial travelling BGK waves and unstable homogeneous states in some W^{s,p} (p>1,s>1+(1/p)) neighborhood. Furthermore, when p=2,we prove that there exist no nontrivial invariant structures in the H^{s} (s>(3/2)) neighborhood of stable homogeneous states. These results suggest the long time dynamics in the W^{s,p} (s>1+(1/p)) and particularly, in the H^{s} (s>(3/2)) neighborhoods of a stable homogeneous state might be relatively simple. We also demonstrate that linear damping holds for initial perturbations in very rough spaces, for linearly stable homogeneous state. This suggests that the contrasting dynamics in W^{s,p} spaces with the critical power s=1+(1/p) is a trully nonlinear phenomena which can not be traced back to the linear level

    Mental models of high reliability systems

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    Reliable performance in complex systems is determined in part by the ade quacy with which mental models of the system capture accurately the dimen sions of system coupling and system complexity. Failure to register coupling and complexity leads the observer to intervene into an imagined technology that does not exist and to convert opportunities for error into actual errors. To decrease the frequency with which this conversion occurs, people can make their models more complex or the systems they monitor less complex. Neither type of change is as daunting as it may appear, and this is illustrated by an analysis of the mental model and system design associated with the invasion of Grenada.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68652/2/10.1177_108602668900300203.pd

    Overcoming the Impasse in Modern Economics

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    This document is the Accepted Manuscript version of the following article: Francesca Gagliardi, and David Gindis, 'Overcoming the Impasse in Modern Economics', Competition and Change, Vol. 15 (4): 336-42, November 2011, doi: 10.1179/102452911X13135903675732. Published by SAGE.Peer reviewe

    The association of smoking and socioeconomic status on cutaneous melanoma: a population‐based, data‐linkage, case–control study

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    BACKGROUND: Previous studies have identified an inverse association between melanoma and smoking; however, data from population-based studies are scarce. OBJECTIVES: To determine the association between smoking and socioeconomic (SES) on the risk of development of melanoma. Furthermore, we sought to determine the implications of smoking and SES on survival. METHODS: We conducted a population-based case-control study. Cases were identified from the Welsh Cancer Intelligence and Surveillance Unit (WCISU) during 2000-2015 and controls from the general population. Smoking and SES were obtained from data linkage with other national databases. The association of smoking status and SES on the incidence of melanoma were assessed using binary logistic regression. Multivariate survival analysis was performed on a melanoma cohort using a Cox proportional hazard model using survival as the outcome. RESULTS: During 2000-2015, 9636 patients developed melanoma. Smoking data were obtained for 7124 (73·9%) of these patients. There were 26 408 controls identified from the general population. Smoking was inversely associated with melanoma incidence [odds ratio (OR) 0·70, 95% confidence interval (CI) 0·65-0·76]. Smoking was associated with an increased overall mortality [hazard ratio (HR) 1·30, 95% CI 1·09-1·55], but not associated with melanoma-specific mortality. Patients with higher SES had an increased association with melanoma incidence (OR 1·58, 95% CI 1·44-1·73). Higher SES was associated with an increased chance of both overall (HR 0·67, 95% CI 0·56-0·81) and disease-specific survival (HR 0·69, 95% CI 0·53-0·90). CONCLUSIONS: Our study has demonstrated that smoking appeared to be associated with reduced incidence of melanoma. Although smoking increases overall mortality, no association was observed with melanoma-specific mortality. Further work is required to determine if there is a biological mechanism underlying this relationship or an alternative explanation, such as survival bias. What's already known about this topic? Previous studies have been contradictory with both negative and positive associations between smoking and the incidence of melanoma reported. Previous studies have either been limited by publication bias because of selective reporting or underpowered. What does this study add? Our large study identified an inverse association between smoking status and melanoma incidence. Although smoking status was negatively associated with overall disease survival, no significant association was noted in melanoma-specific survival. Socioeconomic status remains closely associated with melanoma. Although higher socioeconomic populations are more likely to develop the disease, patients with lower socioeconomic status continue to have a worse prognosis

    The T2K ND280 Off-Axis Pi-Zero Detector

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    The Pi-Zero detector (P{\O}D) is one of the subdetectors that makes up the off-axis near detector for the Tokai-to-Kamioka (T2K) long baseline neutrino experiment. The primary goal for the P{\O}D is to measure the relevant cross sections for neutrino interactions that generate pi-zero's, especially the cross section for neutral current pi-zero interactions, which are one of the dominant sources of background to the electron neutrino appearance signal in T2K. The P{\O}D is composed of layers of plastic scintillator alternating with water bags and brass sheets or lead sheets and is one of the first detectors to use Multi-Pixel Photon Counters (MPPCs) on a large scale.Comment: 17 pages, submitted to NIM

    Exact Theorems Concerning CP and CPT Violations in C=-1 Entangled State of Pseudoscalar Neutral Mesons

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    Neutral pseudoscalar mesons in an entangled or Einstein-Podolsky-Rosen state are routinely produced in phi and B factories. Based on the peculiar properties of an entangled state, we present some general exact theorems about parameters characterizing CP and CPT violations, by using various asymmetries defined for the correlated decays of the two entangled mesons, which are rigorously calculated.Comment: 10 pages, published versio
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