8,184 research outputs found
Detecting change in disturbed areas in Grasslands National Park using remote sensing techniques
Non-Peer ReviewedGrasslands National Park was established in 1984, when it began to acquire land from local land owners as it became available for sale. One of the purposes of this park was to create an area where native prairie can be restored and conserved. Because the park is concerned with creating a natural prairie ecosystem, the extent and spread of introduced species (disturbed areas), is of interest. In response to this interest, the first objective of this project is to analyze the spatial distribution of change between 1984 and 2001 in
disturbed areas within the West Block of Grasslands National Park using remote sensing techniques. The second objective is to evaluate which vegetation indices were best suited to map vegetation change between 1984 and 2001. Normalized Difference Vegetation Index (NDVI), Soil Adjusted Vegetation Index (SAVI) and Simple Ratio (SR) were calculated for both the 1984 and 2001 satellite data, and then each of the vegetation index images were subtracted from one another to reveal the change that had occurred between the two dates. Results showed that the species Summer-cypress was often associated with negative change; while Smooth Brome was possibly associated with areas of positive change, particularly in the north-east corner of the park where the Frenchman River crosses the park boundaries. It was found that NDVI was the best vegetation index to map change in disturbed areas of Grasslands National Park in valleys and high moisture areas, while the SAVI was best suited for dry, upland areas
Complex I dysfunction underlies the glycolytic switch in pulmonary hypertensive smooth muscle cells.
ATP is essential for cellular function and is usually produced through oxidative phosphorylation. However, mitochondrial dysfunction is now being recognized as an important contributing factor in the development cardiovascular diseases, such as pulmonary hypertension (PH). In PH there is a metabolic change from oxidative phosphorylation to mainly glycolysis for energy production. However, the mechanisms underlying this glycolytic switch are only poorly understood. In particular the role of the respiratory Complexes in the mitochondrial dysfunction associated with PH is unresolved and was the focus of our investigations. We report that smooth muscle cells isolated from the pulmonary vessels of rats with PH (PH-PASMC), induced by a single injection of monocrotaline, have attenuated mitochondrial function and enhanced glycolysis. Further, utilizing a novel live cell assay, we were able to demonstrate that the mitochondrial dysfunction in PH-PASMC correlates with deficiencies in the activities of Complexes I-III. Further, we observed that there was an increase in mitochondrial reactive oxygen species generation and mitochondrial membrane potential in the PASMC isolated from rats with PH. We further found that the defect in Complex I activity was due to a loss of Complex I assembly, although the assembly of Complexes II and III were both maintained. Thus, we conclude that loss of Complex I assembly may be involved in the switch of energy metabolism in smooth muscle cells to glycolysis and that maintaining Complex I activity may be a potential therapeutic target for the treatment of PH
Generic Finite Size Enhancement of Pairing in Mesoscopic Fermi Systems
The finite size dependent enhancement of pairing in mesoscopic Fermi systems
is studied under the assumption that the BCS approach is valid and that the two
body force is size independent. Different systems are investigated such as
superconducting metallic grains and films as well atomic nuclei. It is shown
that the finite size enhancement of pairing in these systems is in part due to
the presence of a surface which accounts quite well for the data of nuclei and
explains a good fraction of the enhancement in Al grains.Comment: Updated version 17/02/0
Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung.
There is increasing interest in the potential for metabolic profiling to evaluate the progression of pulmonary hypertension (PH). However, a detailed analysis of the metabolic changes in lungs at the early stage of PH, characterized by increased pulmonary artery pressure but prior to the development of right ventricle hypertrophy and failure, is lacking in a preclinical animal model of PH. Thus, we undertook a study using rats 14 days after exposure to monocrotaline (MCT), to determine whether we could identify early stage metabolic changes prior to the manifestation of developed PH. We observed changes in multiple pathways associated with the development of PH, including activated glycolysis, increased markers of proliferation, disruptions in carnitine homeostasis, increased inflammatory and fibrosis biomarkers, and a reduction in glutathione biosynthesis. Further, our global metabolic profile data compare favorably with prior work carried out in humans with PH. We conclude that despite the MCT-model not recapitulating all the structural changes associated with humans with advanced PH, including endothelial cell proliferation and the formation of plexiform lesions, it is very similar at a metabolic level. Thus, we suggest that despite its limitations it can still serve as a useful preclinical model for the study of PH
Day-ahead allocation of operation reserve in composite power systems with large-scale centralized wind farms
This paper focuses on the day-ahead allocation of operation reserve considering wind power prediction error and network transmission constraints in a composite power system. A two-level model that solves the allocation problem is presented. The upper model allocates operation reserve among subsystems from the economic point of view. In the upper model, transmission constraints of tielines are formulated to represent limited reserve support from the neighboring system due to wind power fluctuation. The lower model evaluates the system on the reserve schedule from the reliability point of view. In the lower model, the reliability evaluation of composite power system is performed by using Monte Carlo simulation in a multi-area system. Wind power prediction errors and tieline constraints are incorporated. The reserve requirements in the upper model are iteratively adjusted by the resulting reliability indices from the lower model. Thus, the reserve allocation is gradually optimized until the system achieves the balance between reliability and economy. A modified two-area reliability test system (RTS) is analyzed to demonstrate the validity of the method.This work was supported by National Natural Science Foundation of China (No. 51277141) and National High Technology Research and Development Program of China (863 Program) (No. 2011AA05A103)
Theoretical Spectra and Atmospheres of Extrasolar Giant Planets
We present a comprehensive theory of the spectra and atmospheres of
irradiated extrasolar giant planets. We explore the dependences on stellar
type, orbital distance, cloud characteristics, planet mass, and surface
gravity. Phase-averaged spectra for specific known extrasolar giant planets
that span a wide range of the relevant parameters are calculated, plotted, and
discussed. The connection between atmospheric composition and emergent spectrum
is explored in detail. Furthermore, we calculate the effect of stellar
insolation on brown dwarfs. We review a variety of representative observational
techniques and programs for their potential for direct detection, in light of
our theoretical expectations, and we calculate planet-to-star flux ratios as a
function of wavelength. Our results suggest which spectral features are most
diagnostic of giant planet atmospheres and reveal the best bands in which to
image planets of whatever physical or orbital characteristics.Comment: 47 pages, plus 36 postscript figures; with minor revisions, accepted
to the Astrophysical Journal, May 10, 2003 issu
Brownian markets
Financial market dynamics is rigorously studied via the exact generalized
Langevin equation. Assuming market Brownian self-similarity, the market return
rate memory and autocorrelation functions are derived, which exhibit an
oscillatory-decaying behavior with a long-time tail, similar to empirical
observations. Individual stocks are also described via the generalized Langevin
equation. They are classified by their relation to the market memory as heavy,
neutral and light stocks, possessing different kinds of autocorrelation
functions
Search for gravitational waves associated with the August 2006 timing glitch of the Vela pulsar
The physical mechanisms responsible for pulsar timing glitches are thought to excite quasinormal mode oscillations in their parent neutron star that couple to gravitational-wave emission. In August 2006, a timing glitch was observed in the radio emission of PSR B0833-45, the Vela pulsar. At the time of the glitch, the two colocated Hanford gravitational-wave detectors of the Laser Interferometer Gravitational wave observatory (LIGO) were operational and taking data as part of the fifth LIGO science run (S5). We present the first direct search for the gravitational-wave emission associated with oscillations of the fundamental quadrupole mode excited by a pulsar timing glitch. No gravitational-wave detection
candidate was found. We place Bayesian 90% confidence upper limits of 6.3 x 10^(-21) to 1.4 x 10^(-20) on the peak intrinsic strain amplitude of gravitational-wave ring-down signals, depending on which spherical harmonic mode is excited. The corresponding range of energy upper limits is 5.0 x 10^(-44) to 1.3 x 10^(-45) erg
Two New Candidate Planets in Eccentric Orbits
Doppler measurements of two G-type main-sequence stars, HD210277 and
HD168443, reveal Keplerian variations that imply the presence of companions
with masses (M sin i) of 1.28 and 5.04 M_Jup and orbital periods of 437 d and
58 d, respectively. The orbits have large eccentricities of e=0.45 and e=0.54,
respectively. All 9 known extrasolar planet candidates with a=0.2-2.5 AU have
orbital eccentricities greater than 0.1, higher than that of Jupiter (e=0.05).
Eccentric orbits may result from gravitational perturbations imposed by other
orbiting planets or stars, by passing stars in the dense star-forming cluster,
or by the protoplanetary disk. Based on published studies and our near-IR
adaptive optics images, HD210277 appears to be a single star. However, HD168443
exhibits a long-term velocity trend consistent with a close stellar companion,
as yet undetected directly.Comment: AASTeX, 31 pages including 10 Postscript figures, to appear in the
Astrophysical Journal (July 1999
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