Human Rights and Intellectual Property: Mapping the Global Interface

Human Rights and Intellectual Property: Mapping the Global Interface explores the intersections between intellectual property and human rights law and policy. The relationship between these two fields has captured the attention of governments, policymakers, and activist communities in a diverse array of international and domestic political and judicial venues. These actors often raise human rights arguments as counterweights to the expansion of intellectual property in areas including freedom of expression, public health, education, privacy, agriculture, and the rights of indigenous peoples. At the same time, the creators and owners of intellectual property are asserting a human rights justification for the expansion of legal protections. The book explores the legal, institutional, and political implications of these competing claims in three ways: (1) by offering a framework for exploring the connections and divergences between these subjects; (2) by identifying the pathways along which jurisprudence, policy, and political discourse are likely to evolve; and (3) by serving as a teaching and learning resource for scholars, activists, and students. This excerpt contains the book\u27s table of contents, preface, and concluding chapter

Models of the diffuse radar backscatter from Mars

The topographies of several debris flow units near the Mount St. Helens Volcano were measured at lateral scales of millimeters to meters in September 1990. The objective was to measure the surface roughness of the debris flows at scales smaller than, on the order of, and larger that the radar wavelength of common remote sensing radars. A laser profiling system and surveying instruments were used to obtain elevation data for square areas that varied in size from 10 to 32 cm. The elevation data were converted to estimates of the power spectrum of surface roughness. The conversions were based upon standard periodogram techniques, and upon a modified spectral estimation technique that was developed

A Peptide Core Motif for Binding to Heterotrimeric G Protein α Subunits

Recently, in vitro selection using mRNA display was used to identify a novel peptide sequence that binds with high affinity to G{alpha}i1. The peptide was minimized to a 9-residue sequence (R6A-1) that retains high affinity and specificity for the GDP-bound state of G{alpha}i1 and acts as a guanine nucleotide dissociation inhibitor (GDI). Here we demonstrate that the R6A-1 peptide interacts with G{alpha} subunits representing all four G protein classes, acting as a core motif for G{alpha} interaction. This contrasts with the consensus G protein regulatory(GPR) sequence, a 28-mer peptide GDI derived from the GoLoco (G{alpha}i/0-Loco interaction)/GPR motif that shares no homology with R6A-1 and binds only to G{alpha}i1-3 in this assay. Binding of R6A-1 is generally specific to the GDP-bound state of the G{alpha} subunits and excludes association with G{beta}{gamma}. R6A-G{alpha}i1 complexes are resistant to trypsin digestion and exhibit distinct stability in the presence of Mg2+, suggesting that the R6A and GPR peptides exert their activities using different mechanisms. Studies using G{alpha}i1/G{alpha}s chimeras identify two regions of G{alpha}i1 (residues 1–35 and 57–88) as determinants for strong R6A-Gi{alpha}1 interaction. Residues flanking the R6A-1 peptide confer unique binding properties, indicating that the core motif could be used as a starting point for the development of peptides exhibiting novel activities and/or specificity for particular G protein subclasses or nucleotide-bound states

Exploring Relationships Between Passion and Attitudes Toward Performance Enhancing Drugs in Canadian Collegiate Sport Contexts

The purpose of this study was to explore relationships between passion and attitudes toward performance enhancing drugs (PEDs). Participants were 587 male and female varsity and coed intramural athletes from four Southern Ontario universities. Athletes completed the passion scale (Vallerand et al., 2003) and the performance enhancement attitudes scale (Petróczi, 2006). Full sample regression analyze revealed that higher scores on obsessive passion items were associated with more permissive attitudes toward PEDs (B =, 26, p < .001), while higher scores on harmonious passion items were associated with less permissive attitudes toward PEDs (B = -.29, p < .001). Moreover, obsessive passion emerged as a significant positive predictor of attitudes toward PEDs in all study contexts (i.e., coed recreational athletes, male/female varsity athletes). Implications for sport administrators, study limitations, and possible avenues for future research are discussed

Magnetic excitations of spin and orbital moments in cobalt oxide

Magnetic and phonon excitations in the antiferromagnet CoO with an unquenched orbital angular momentum are studied by neutron scattering. Results of energy scans in several Brillouin zones in the (HHL) plane for energy transfers up to 16 THz are presented. The measurements were performed in the antiferromagnetic ordered state at 6 K (well below TN~290 K) as well as in the paramagnetic state at 450 K. Several magnetic excitation modes are identified from the dependence of their intensity on wavevector and temperature. Within a Hund's rule model the excitations correspond to fluctuations of coupled orbital and spin degrees of freedom whose bandwidth is controlled by interionic superexchange. The different ordering domains give rise to several magnetic peaks at each wavevector transfer.Comment: Accepted for publication in Canadian Journal of Physic

Diffusion mechanisms of localised knots along a polymer

We consider the diffusive motion of a localized knot along a linear polymer chain. In particular, we derive the mean diffusion time of the knot before it escapes from the chain once it gets close to one of the chain ends. Self-reptation of the entire chain between either end and the knot position, during which the knot is provided with free volume, leads to an L^3 scaling of diffusion time; for sufficiently long chains, subdiffusion will enhance this time even more. Conversely, we propose local ``breathing'', i.e., local conformational rearrangement inside the knot region (KR) and its immediate neighbourhood, as additional mechanism. The contribution of KR-breathing to the diffusion time scales only quadratically, L^2, speeding up the knot escape considerably and guaranteeing finite knot mobility even for very long chains.Comment: 7 pages, 2 figures. Accepted to Europhys. Let

Experiments on Visual Acuity and the Visibility of Markings on the Ground in Long-duration Earth-Orbital Space Flight

Visual acuity and visibility of markings on ground in long duration earth orbital space fligh

SeaWiFS technical report series. Volume 5: Ocean optics protocols for SeaWiFS validation

Protocols are presented for measuring optical properties, and other environmental variables, to validate the radiometric performance of the Sea-viewing Wide Field-of-view Sensor (SeaWiFS), and to develop and validate bio-optical algorithms for use with SeaWiFS data. The protocols are intended to establish foundations for a measurement strategy to verify the challenging SeaWiFS accuracy goals of 5 percent in water-leaving radiances and 35 percent in chlorophyll alpha concentration. The protocols first specify the variables which must be measured, and briefly review rationale. Subsequent chapters cover detailed protocols for instrument performance specifications, characterizing and calibration instruments, methods of making measurements in the field, and methods of data analysis. These protocols were developed at a workshop sponsored by the SeaWiFS Project Office (SPO) and held at the Naval Postgraduate School in Monterey, California (9-12 April, 1991). This report is the proceedings of that workshop, as interpreted and expanded by the authors and reviewed by workshop participants and other members of the bio-optical research community. The protocols are a first prescription to approach unprecedented measurement accuracies implied by the SeaWiFS goals, and research and development are needed to improve the state-of-the-art in specific areas. The protocols should be periodically revised to reflect technical advances during the SeaWiFS Project cycle

Recent Extreme Ultraviolet Solar Spectra and Spectroheliograms

Extreme ultraviolet solar spectra and spectroheliogram analyse

Nudges and other moral technologies in the context of power: Assigning and accepting responsibility

Strawson argues that we should understand moral responsibility in terms of our practices of holding responsible and taking responsibility. The former covers what is commonly referred to as backward-looking responsibility , while the latter covers what is commonly referred to as forward-looking responsibility . We consider new technologies and interventions that facilitate assignment of responsibility. Assigning responsibility is best understood as the second- or third-personal analogue of taking responsibility. It establishes forward-looking responsibility. But unlike taking responsibility, it establishes forward-looking responsibility in someone else. When such assignments are accepted, they function in such a way that those to whom responsibility has been assigned face the same obligations and are susceptible to the same reactive attitudes as someone who takes responsibility. One family of interventions interests us in particular: nudges. We contend that many instances of nudging tacitly assign responsibility to nudgees for actions, values, and relationships that they might not otherwise have taken responsibility for. To the extent that nudgees tacitly accept such assignments, they become responsible for upholding norms that would otherwise have fallen under the purview of other actors. While this may be empowering in some cases, it can also function in such a way that it burdens people with more responsibility that they can (reasonably be expected to) manage