59 research outputs found
Corrosion resistance of anodic layers grown on 304L stainless steel at different anodizing times and stirring speeds
Different chemical and physical treatments have been used to improve the properties and functionalities of steels. Anodizing is one of the most promising treatments, due to its versatility and easy industrial implementation. It allows the growth of nanoestructured oxide films with interesting properties able to be employed in different industrial sectors. The present work studies the influence of the anodizing time (15, 30, 45 and 60 min), as well as the stirring speed (0, 200, 400, and 600 rpm), on the morphology and the corrosion resistance of the anodic layers grown in 304L stainless steel. The anodic layers were characterized morphologically, compositionally, and electrochemically, in order to determine the influence of the anodization parameters on their corrosion behavior in a 0.6 mol L-1 NaCl solution. The results show that at 45 and 60 min anodizing times, the formation of two microstructures is favored, associated with the collapse of the nanoporous structures at the metal-oxide interphace. However, both the stirring speed and the anodizing time have a negligeable effect on the corrosion behavior of the anodized 304L SS samples, since their electrochemical values are similar to those of the non-anodized ones
Diplopia Is Frequent and Associated with Motor and Non-Motor Severity in Parkinsonâs Disease: Results from the COPPADIS Cohort at 2-Year Follow-Up
Malaltia de Parkinson; Fenotip; TremolorEnfermedad de Parkinson; Fenotipo; TemblorParkinsonâs disease; Phenotype; TremorBackground and objective: Diplopia is relatively common in Parkinsonâs disease (PD) but is still understudied. Our aim was to analyze the frequency of diplopia in PD patients from a multicenter Spanish cohort, to compare the frequency with a control group, and to identify factors associated with it. Patients and Methods: PD patients who were recruited from January 2016 to November 2017 (baseline visit; V0) and evaluated again at a 2-year ± 30 days follow-up (V2) from 35 centers of Spain from the COPPADIS cohort were included in this longitudinal prospective study. The patients and controls were classified as âwith diplopiaâ or âwithout diplopiaâ according to item 15 of the Non-Motor Symptoms Scale (NMSS) at V0, V1 (1-year ± 15 days), and V2 for the patients and at V0 and V2 for the controls. Results: The frequency of diplopia in the PD patients was 13.6% (94/691) at V0 (1.9% in controls [4/206]; p < 0.0001), 14.2% (86/604) at V1, and 17.1% (86/502) at V2 (0.8% in controls [1/124]; p < 0.0001), with a period prevalence of 24.9% (120/481). Visual hallucinations at any visit from V0 to V2 (OR = 2.264; 95%CI, 1.269â4.039; p = 0.006), a higher score on the NMSS at V0 (OR = 1.009; 95%CI, 1.012â1.024; p = 0.015), and a greater increase from V0 to V2 on the Unified Parkinsonâs Disease Rating ScaleâIII (OR = 1.039; 95%CI, 1.023â1.083; p < 0.0001) and Neuropsychiatric Inventory (OR = 1.028; 95%CI, 1.001â1.057; p = 0.049) scores were independent factors associated with diplopia (R2 = 0.25; Hosmer and Lemeshow test, p = 0.716). Conclusions: Diplopia represents a frequent symptom in PD patients and is associated with motor and non-motor severity.Solano Vila B. has received honoraria for educational presentations and advice service by UCB, Zambon, Teva, Abbvie, Bia
NEXT-CRAB-0: A High Pressure Gaseous Xenon Time Projection Chamber with a Direct VUV Camera Based Readout
The search for neutrinoless double beta decay () remains one
of the most compelling experimental avenues for the discovery in the neutrino
sector. Electroluminescent gas-phase time projection chambers are well suited
to searches due to their intrinsically precise energy
resolution and topological event identification capabilities. Scalability to
ton- and multi-ton masses requires readout of large-area electroluminescent
regions with fine spatial resolution, low radiogenic backgrounds, and a
scalable data acquisition system. This paper presents a detector prototype that
records event topology in an electroluminescent xenon gas TPC via VUV
image-intensified cameras. This enables an extendable readout of large tracking
planes with commercial devices that reside almost entirely outside of the
active medium.Following further development in intermediate scale
demonstrators, this technique may represent a novel and enlargeable method for
topological event imaging in .Comment: 32 Pages, 22 figure
A Compact Dication Source for Ba Tagging and Heavy Metal Ion Sensor Development
We present a tunable metal ion beam that delivers controllable ion currents
in the picoamp range for testing of dry-phase ion sensors. Ion beams are formed
by sequential atomic evaporation and single or multiple electron impact
ionization, followed by acceleration into a sensing region. Controllability of
the ionic charge state is achieved through tuning of electrode potentials that
influence the retention time in the ionization region. Barium, lead, and cobalt
samples have been used to test the system, with ion currents identified and
quantified using a quadrupole mass analyzer. Realization of a clean
ion beam within a bench-top system represents an important
technical advance toward the development and characterization of barium tagging
systems for neutrinoless double beta decay searches in xenon gas. This system
also provides a testbed for investigation of novel ion sensing methodologies
for environmental assay applications, with dication beams of Pb and
Cd also demonstrated for this purpose
Political & Quasi-Adjudicative Dispute Settlement Models in European Union Free Trade Agreements - Is the Quasi-Adjudicative Model a Trend or is it Just Another Model?
Ba+2 ion trapping using organic submonolayer for ultra-low background neutrinoless double beta detector
If neutrinos are their own antiparticles the otherwise-forbidden nuclear reaction known as neutrinoless double beta decay can occur. The very long lifetime expected for these exceptional events makes its detection a daunting task. In order to conduct an almost background-free experiment, the NEXT collaboration is investigating novel synthetic molecular sensors that may capture the Ba dication produced in the decay of certain Xe isotopes in a high-pressure gas experiment. The use of such molecular detectors immobilized on surfaces must be explored in the ultra-dry environment of a xenon gas chamber. Here, using a combination of highly sensitive surface science techniques in ultra-high vacuum, we demonstrate the possibility of employing the so-called Fluorescent Bicolor Indicator as the molecular component of the sensor. We unravel the ion capture process for these molecular indicators immobilized on a surface and explain the origin of the emission fluorescence shift associated to the ion trapping
Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: Involvement of CB2
Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases
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