384 research outputs found
The influence of barefoot and barefoot inspired footwear on the kinetics and kinematics of running in comparison to conventional running shoes.
Barefoot running has experienced a resurgence in footwear biomechanics literature, based on the supposition that it serves to reduce the occurrence of overuse injuries in comparison to conventional shoe models. This consensus has lead footwear manufacturers to develop shoes which aim to mimic the mechanics of barefoot locomotion.
This study compared the impact kinetics and 3-D joint angular kinematics observed whilst running: barefoot, in conventional cushioned running shoes and in shoes designed to integrate the perceived benefits of barefoot locomotion. The aim of the current investigation was therefore to determine whether differences in impact kinetics exist between the footwear conditions and whether shoes which aim to simulate barefoot movement patterns can closely mimic the 3-D kinematics of barefoot running.
Twelve participants ran at 4.0 m.s-1±5% in each footwear condition. Angular joint kinematics from the hip, knee and ankle in the sagittal, coronal and transverse planes were measured using an eight camera motion analysis system. In addition simultaneous tibial acceleration and ground reaction forces were obtained. Impact parameters and joint kinematics were subsequently compared using repeated measures ANOVAs.
The kinematic analysis indicates that in comparison to the conventional and barefoot inspired shoes that running barefoot was associated significantly greater plantar-flexion at footstrike and range of motion to peak dorsiflexion. Furthermore, the kinetic analysis revealed that compared to the conventional footwear impact parameters were significantly greater in the barefoot condition.
Therefore this study suggests that barefoot running is associated with impact kinetics linked to an increased risk of overuse injury, when compared to conventional shod running. Furthermore, the mechanics of the shoes which aim to simulate barefoot movement patterns do not appear to closely mimic the kinematics of barefoot locomotion
Using Synchronic and Diachronic Relations for Summarizing Multiple Documents Describing Evolving Events
In this paper we present a fresh look at the problem of summarizing evolving
events from multiple sources. After a discussion concerning the nature of
evolving events we introduce a distinction between linearly and non-linearly
evolving events. We present then a general methodology for the automatic
creation of summaries from evolving events. At its heart lie the notions of
Synchronic and Diachronic cross-document Relations (SDRs), whose aim is the
identification of similarities and differences between sources, from a
synchronical and diachronical perspective. SDRs do not connect documents or
textual elements found therein, but structures one might call messages.
Applying this methodology will yield a set of messages and relations, SDRs,
connecting them, that is a graph which we call grid. We will show how such a
grid can be considered as the starting point of a Natural Language Generation
System. The methodology is evaluated in two case-studies, one for linearly
evolving events (descriptions of football matches) and another one for
non-linearly evolving events (terrorist incidents involving hostages). In both
cases we evaluate the results produced by our computational systems.Comment: 45 pages, 6 figures. To appear in the Journal of Intelligent
Information System
Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties
The X-ray structure of an immunoglobulin light-chain dimer isolated from the urine as a 'Bence-Jones protein' from a patient with multiple myeloma and amyloidosis (Sea) was determined at 1.94 Angstrom resolution and refined to R and R-free factors of 0.22 and 0.25, respectively. This 'amyloidogenic' protein crystallized in the orthorhombic P2(1)2(1)2(1) space group with unit-cell parameters a=48.28, b=83.32, c=112.59 Angstrom as determined at 100 K. In the vital organs (heart and kidneys), the equivalent of the urinary protein produced fibrillar amyloid deposits which were fatal to the patient. Compared with the amyloidogenic Mcg light-chain dimer, the Sea protein was highly soluble in aqueous solutions and only crystallized at concentrations approaching 100 mg ml(-1). Both the Sea and Mcg proteins packed into crystals in highly ordered arrangements typical of strongly diffracting crystals of immunoglobulin fragments. Overall similarities and significant differences in the three-dimensional structures and crystalline properties are discussed for the Sea and Mcg Bence-Jones proteins, which together provide a generalized model of abnormalities present in lambda chains, facilitating a better understanding of amyloidosis of light-chain origin (AL)
The Crystallography of Color Superconductivity
We develop the Ginzburg-Landau approach to comparing different possible
crystal structures for the crystalline color superconducting phase of QCD, the
QCD incarnation of the Larkin-Ovchinnikov-Fulde-Ferrell phase. In this phase,
quarks of different flavor with differing Fermi momenta form Cooper pairs with
nonzero total momentum, yielding a condensate that varies in space like a sum
of plane waves. We work at zero temperature, as is relevant for compact star
physics. The Ginzburg-Landau approach predicts a strong first-order phase
transition (as a function of the chemical potential difference between quarks)
and for this reason is not under quantitative control. Nevertheless, by
organizing the comparison between different possible arrangements of plane
waves (i.e. different crystal structures) it provides considerable qualitative
insight into what makes a crystal structure favorable. Together, the
qualitative insights and the quantitative, but not controlled, calculations
make a compelling case that the favored pairing pattern yields a condensate
which is a sum of eight plane waves forming a face-centered cubic structure.
They also predict that the phase is quite robust, with gaps comparable in
magnitude to the BCS gap that would form if the Fermi momenta were degenerate.
These predictions may be tested in ultracold gases made of fermionic atoms. In
a QCD context, our results lay the foundation for a calculation of vortex
pinning in a crystalline color superconductor, and thus for the analysis of
pulsar glitches that may originate within the core of a compact star.Comment: 41 pages, 13 figures, 1 tabl
Overcoming the Challenges Associated with Image-based Mapping of Small Bodies in Preparation for the OSIRIS-REx Mission to (101955) Bennu
The OSIRIS-REx Asteroid Sample Return Mission is the third mission in NASA's
New Frontiers Program and is the first U.S. mission to return samples from an
asteroid to Earth. The most important decision ahead of the OSIRIS-REx team is
the selection of a prime sample-site on the surface of asteroid (101955) Bennu.
Mission success hinges on identifying a site that is safe and has regolith that
can readily be ingested by the spacecraft's sampling mechanism. To inform this
mission-critical decision, the surface of Bennu is mapped using the OSIRIS-REx
Camera Suite and the images are used to develop several foundational data
products. Acquiring the necessary inputs to these data products requires
observational strategies that are defined specifically to overcome the
challenges associated with mapping a small irregular body. We present these
strategies in the context of assessing candidate sample-sites at Bennu
according to a framework of decisions regarding the relative safety,
sampleability, and scientific value across the asteroid's surface. To create
data products that aid these assessments, we describe the best practices
developed by the OSIRIS-REx team for image-based mapping of irregular small
bodies. We emphasize the importance of using 3D shape models and the ability to
work in body-fixed rectangular coordinates when dealing with planetary surfaces
that cannot be uniquely addressed by body-fixed latitude and longitude.Comment: 31 pages, 10 figures, 2 table
Monitoring international migration flows in Europe. Towards a statistical data base combining data from different sources
The paper reviews techniques developed in demography, geography and statistics that are useful for bridging the gap between available data on international migration flows and the information required for policy making and research. The basic idea of the paper is as follows: to establish a coherent and consistent data base that contains sufficiently detailed, up-to-date and accurate information, data from several sources should be combined. That raises issues of definition and measurement, and of how to combine data from different origins properly. The issues may be tackled more easily if the statistics that are being compiled are viewed as different outcomes or manifestations of underlying stochastic processes governing migration. The link between the processes and their outcomes is described by models, the parameters of which must be estimated from the available data. That may be done within the context of socio-demographic accounting. The paper discusses the experience of the U.S. Bureau of the Census in combining migration data from several sources. It also summarizes the many efforts in Europe to establish a coherent and consistent data base on international migration.
The paper was written at IIASA. It is part of the Migration Estimation Study, which is a collaborative IIASA-University of Groningen project, funded by the Netherlands Organization for Scientific Research (NWO). The project aims at developing techniques to obtain improved estimates of international migration flows by country of origin and country of destination
A framework for the local information dynamics of distributed computation in complex systems
The nature of distributed computation has often been described in terms of
the component operations of universal computation: information storage,
transfer and modification. We review the first complete framework that
quantifies each of these individual information dynamics on a local scale
within a system, and describes the manner in which they interact to create
non-trivial computation where "the whole is greater than the sum of the parts".
We describe the application of the framework to cellular automata, a simple yet
powerful model of distributed computation. This is an important application,
because the framework is the first to provide quantitative evidence for several
important conjectures about distributed computation in cellular automata: that
blinkers embody information storage, particles are information transfer agents,
and particle collisions are information modification events. The framework is
also shown to contrast the computations conducted by several well-known
cellular automata, highlighting the importance of information coherence in
complex computation. The results reviewed here provide important quantitative
insights into the fundamental nature of distributed computation and the
dynamics of complex systems, as well as impetus for the framework to be applied
to the analysis and design of other systems.Comment: 44 pages, 8 figure
Modulational instability, solitons and beam propagation in spatially nonlocal nonlinear media
We present an overview of recent advances in the understanding of optical
beams in nonlinear media with a spatially nonlocal nonlinear response. We
discuss the impact of nonlocality on the modulational instability of plane
waves, the collapse of finite-size beams, and the formation and interaction of
spatial solitons.Comment: Review article, will be published in Journal of Optics B, special
issue on Optical Solitons, 6 figure
Stable spinning optical solitons in three dimensions
We introduce spatiotemporal spinning solitons (vortex tori) of the
three-dimensional nonlinear Schrodinger equation with focusing cubic and
defocusing quintic nonlinearities. The first ever found completely stable
spatiotemporal vortex solitons are demonstrated. A general conclusion is that
stable spinning solitons are possible as a result of competition between
focusing and defocusing nonlinearities.Comment: 4 pages, 6 figures, accepted to Phys. Rev. Let
Structuring and integrating human knowledge in demand forecasting: a judgemental adjustment approach
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