New business histories! Plurality in business history research methods

We agree with de Jong et al.'s argument that business historians should make their methods more explicit and welcome a more general debate about the most appropriate methods for business historical research. But rather than advocating one ‘new business history’, we argue that contemporary debates about methodology in business history need greater appreciation for the diversity of approaches that have developed in the last decade. And while the hypothesis-testing framework prevalent in the mainstream social sciences favoured by de Jong et al. should have its place among these methodologies, we identify a number of additional streams of research that can legitimately claim to have contributed novel methodological insights by broadening the range of interpretative and qualitative approaches to business history. Thus, we reject privileging a single method, whatever it may be, and argue instead in favour of recognising the plurality of methods being developed and used by business historians – both within their own field and as a basis for interactions with others

Prevalence and associated harm of engagement in self-Asphyxial behaviours ('choking game') in young people:A systematic review

OBJECTIVE: To assess the prevalence of engagement in self-asphyxial (risk-taking) behaviour (SAB) (‘choking game’) and associated morbidity and mortality in children and young people up to age 20. DESIGN: Systematic literature review. SEARCH STRATEGY: Electronic database search of MEDLINE, Embase, PsycINFO, CINAHL, PubMed, Web of Science Core Collection, BIOSIS citation index and the Cochrane register with no language or date limits applied. References of key papers were reviewed, and experts were contacted to identify additional relevant papers. ELIGIBILITY CRITERIA: Systematic reviews, cross-sectional, cohort and case–control studies, and case reports examining SAB with regard to individuals aged 0–20 years, without explicitly stated autoerotic, suicidal or self-harm intentions were included. RESULTS: Thirty-six relevant studies were identified, and SAB was reported in 10 countries. In North America, France and Colombia, awareness of SAB ranged from 36% to 91% across studies/settings, and the median lifetime prevalence of engagement in SAB was 7.4%. Six studies identified the potential for SAB to be associated with engagement in other risk behaviours. Ninety-nine fatal cases were reported. Of the 24 cases described in detail, most occurred when individuals engaged in SAB alone and used a ligature. CONCLUSIONS: The current evidence on SAB among young people is limited, and stems predominantly from North America and France. Awareness of SAB among young people is high, and engagement varies by setting. Further research is needed to understand the level of risk and harm associated with SAB, and to determine the appropriate public health response

The Hunt for Exomoons with Kepler (HEK): IV. A Search for Moons around Eight M-Dwarfs

With their smaller radii and high cosmic abundance, transiting planets around cool stars hold a unique appeal. As part of our on-going project to measure the occurrence rate of extrasolar moons, we here present results from a survey focussing on eight Kepler planetary candidates associated with M-dwarfs. Using photodynamical modeling and Bayesian multimodal nested sampling, we find no compelling evidence for an exomoon in these eight systems. Upper limits on the presence of such bodies probe down to $\sim0.4M_{\oplus}$ in the best case. For KOI-314, we are able to confirm the planetary nature of two out of the three known transiting candidates using transit timing variations. Of particular interest is KOI-314c, which is found to have a mass of $1.0_{-0.3}^{+0.4}M_{\oplus}$, making it the lowest mass transiting planet discovered to date. With a radius of $1.61_{-0.15}^{+0.16}R_{\oplus}$, this Earth-mass world is likely enveloped by a significant gaseous envelope comprising $\geq17_{-13}^{+12}$% of the planet by radius. We find evidence to support the planetary nature of KOI-784 too via transit timing, but we advocate further observations to verify the signals. In both systems, we infer that the inner planet has a higher density than the outer world, which may be indicative of photo-evaporation. These results highlight both the ability of Kepler to search for sub-Earth mass moons and the exciting ancillary science which often results from such efforts.Comment: 15 pages, 13 figures, 6 tables. Accepted in Ap

The Hunt for Exomoons with Kepler (HEK): II. Analysis of Seven Viable Satellite-Hosting Planet Candidates

From the list of 2321 transiting planet candidates announced by the Kepler Mission, we select seven targets with favorable properties for the capacity to dynamically maintain an exomoon and present a detectable signal. These seven candidates were identified through our automatic target selection (TSA) algorithm and target selection prioritization (TSP) filtering, whereby we excluded systems exhibiting significant time-correlated noise and focussed on those with a single transiting planet candidate of radius less than 6 Earth radii. We find no compelling evidence for an exomoon around any of the seven KOIs but constrain the satellite-to-planet mass ratios for each. For four of the seven KOIs, we estimate a 95% upper quantile of M_S/M_P<0.04, which given the radii of the candidates, likely probes down to sub-Earth masses. We also derive precise transit times and durations for each candidate and find no evidence for dynamical variations in any of the KOIs. With just a few systems analyzed thus far in the in-going HEK project, projections on eta-moon would be premature, but a high frequency of large moons around Super-Earths/Mini-Neptunes would appear to be incommensurable with our results so far.Comment: 32 pages, 11 figures, 23 tables, Accepted to Ap

Exomoon habitability constrained by energy flux and orbital stability

Detecting massive satellites of extrasolar planets has now become feasible, which led naturally to questions about their habitability. In a previous study we presented constraints on the habitability of moons from stellar and planetary illumination as well as from tidal heating. Here I refine our model by including the effect of eclipses on the orbit-averaged illumination. Moons in low-mass stellar systems must orbit their planet very closely to remain bound, which puts them at risk of strong tidal heating. I first describe the effect of eclipses on stellar illumination of satellites. Then I calculate the orbit-averaged energy flux including illumination from the planet and tidal heating. Habitability is defined by a scaling relation at which a moon loses its water by the runaway greenhouse process. As a working hypothesis, orbital stability is assumed if the moon's orbital period is less than 1/9 of the planet's orbital period. Due to eclipses, a satellite in a close orbit can experience a reduction in orbit-averaged stellar flux by up to about 6%. The smaller the semi-major axis and the lower the inclination of the moon's orbit, the stronger the reduction. I find a lower mass limit of ~0.2M_sun for exomoon host stars to avoid the runaway greenhouse effect. Precise estimates depend on the satellite's orbital eccentricity. Deleterious effects on exomoon habitability may occur up to ~0.5M_sun. Although the habitable zone lies close to low-mass stars, which allows for many transits of planet-moon binaries within a given observation cycle, resources should not be spent to trace habitable satellites around them. Gravitational perturbations by the star, another planet, or another satellite induce eccentricities that likely make any moon uninhabitable. Estimates for individual systems require dynamical simulations that include perturbations among all bodies and tidal heating in the satellite.Comment: 4 pages, 2 figures, accepted by A&

Total Chiral Symmetry Breaking during Crystallization: Who needs a "Mother Crystal"?

Processes that can produce states of broken chiral symmetry are of particular interest to physics, chemistry and biology. Chiral symmetry breaking during crystallization of sodium chlorate occurs via the production of secondary crystals of the same handedness from a single "mother crystal" that seeds the solution. Here we report that a large and "symmetric" population of D- and L-crystals moves into complete chiral purity disappearing one of the enantiomers. This result shows: (i) a new symmetry breaking process incompatible with the hypothesis of a single "mother crystal"; (ii) that complete symmetry breaking and chiral purity can be achieved from an initial system with both enantiomers. These findings demand a new explanation to the process of total symmetry breaking in crystallization without the intervention of a "mother crystal" and open the debate on this fascinating phenomenon. We present arguments to show that our experimental data can been explained with a new model of "complete chiral purity induced by nonlinear autocatalysis and recycling".Comment: 5 pages, 4 figures, Added reference

The Hunt for Exomoons with Kepler (HEK): III. The First Search for an Exomoon around a Habitable-Zone Planet

Kepler-22b is the first transiting planet to have been detected in the habitable-zone of its host star. At 2.4 Earth radii, Kepler-22b is too large to be considered an Earth-analog, but should the planet host a moon large enough to maintain an atmosphere, then the Kepler-22 system may yet possess a telluric world. Aside from being within the habitable-zone, the target is attractive due to the availability of previously measured precise radial velocities and low intrinsic photometric noise, which has also enabled asteroseismology studies of the star. For these reasons, Kepler-22b was selected as a target-of-opportunity by the 'Hunt for Exomoons with Kepler' (HEK) project. In this work, we conduct a photodynamical search for an exomoon around Kepler-22b leveraging the transits, radial velocities and asteroseismology plus several new tools developed by the HEK project to improve exomoon searches. We find no evidence for an exomoon around the planet and exclude moons of mass >0.5 Earth masses to 95% confidence. By signal injection and blind retrieval, we demonstrate that an Earth-like moon is easily detected for this planet even when the time-correlated noise of the data set is taken into account. We provide updated parameters for the planet Kepler-22b including a revised mass of <53 Earth masses to 95% confidence and an eccentricity of 0.13(-0.13)(+0.36) by exploiting Single-body Asterodensity Profiling (SAP). Finally, we show that Kepler-22b has a >95% probability of being within the empirical habitable-zone but a <5% probability of being within the conservative habitable-zone.Comment: 19 pages, 11 figures, 7 tables. Accepted in ApJ. Planet-moon transit animations available at https://www.cfa.harvard.edu/~dkipping/kepler22.htm

Women’s knowledge, attitudes and views of preconception health and intervention delivery methods:a cross-sectional survey

Background: Several preconception exposures have been associated with adverse pregnancy, birth and postpartum outcomes. However, few studies have investigated women’s knowledge of and attitudes towards preconception health, and the acceptability of potential intervention methods. Methods: Seven primary care centres in the West of England posted questionnaires to 4330 female patients aged 18 to 48 years. Without providing examples, we asked women to list maternal preconception exposures that might affect infant and maternal outcomes, and assessed their knowledge of nine literature-derived risk factors. Attitudes towards preconception health (interest, intentions, self-efficacy and perceived awareness and importance) and the acceptability of intervention delivery methods were also assessed. Multivariable multilevel regression examined participant characteristics associated with these outcomes. Results: Of those who received questionnaires, 835 (19.3%) responded. Women were most aware of the preconception risk factors of diet (86.0%) and physical activity (79.2%). Few were aware of weight (40.1%), folic acid (32.9%), abuse (6.3%), advanced age (5.9%) and interpregnancy intervals (0.2%), and none mentioned interpregnancy weight change or excess iron intake. After adjusting for demographic and reproductive covariates, women aged 18–24-years (compared to 40–48-year-olds) and nulligravid women were less aware of the benefit of preconception folic acid supplementation (adjusted odds ratios (aOR) for age: 4.30 [2.10–8.80], gravidity: aOR 2.48 [1.70–3.62]). Younger women were more interested in learning more about preconception health (aOR 0.37 [0.21–0.63]) but nulligravid women were less interested in this (aOR 1.79 [1.30–2.46]). Women with the lowest household incomes (versus the highest) were less aware of preconception weight as a risk factor (aOR: 3.11 [1.65–5.84]) and rated the importance of preconception health lower (aOR 3.38 [1.90–6.00]). The most acceptable information delivery methods were websites/apps (99.5%), printed healthcare materials (98.6%), family/partners (96.3%), schools (94.4%), television (91.9%), pregnancy tests (91.0%) and doctors, midwives and nurses (86.8–97.0%). Dentists (23.9%) and hairdressers/beauticians (18.1%) were the least acceptable. Conclusions: Our findings demonstrate a need to promote awareness of preconception risk factors and motivation for preconception health changes, particularly amongst younger and nulligravid women and women with lower incomes. Interventions to improve preconception health should focus on communication from healthcare professionals, schools, family members, and digital media