307 research outputs found

    Concentrations of some toxic and trace elements in wild boar (Sus scrofa) organs and tissues in different areas of the Province of Viterbo, Central Italy

    Get PDF
    The aim of the present study was to determine heavy metal reference levels for exposure and risk assessment studies on a local scale. We measured lead (Pb), chromium (Cr), zinc (Zn), copper (Cu) and cadmium (Cd) content in edible tissues and organs of wild boars harvested in dif- ferent areas of the Province of Viterbo, Central Italy. The average levels of cadmium recorded in 75 wild boars were 0.085, 0.079 and 1.052 mg Cd kg–1 wet weight (w.w.) in the liver, muscle and kidney, respectively. The majority of the muscle samples and some of the liver samples contained levels of heavy metal that were over the legal limit [EU Maximum Residue Levels (MRLs)] for pigs. Our data are similar to or lower than the val- ues reported in most of the available literature. For Pb concentration, the average values record- ed were 0.318, 0.126 and 0.298 mg kg–1 w.w. in the liver, muscle and kidney, respectively. The sam- ples that were non-compliant with regulatory limits (MRLs) for pigs were registered only for muscle. Available data on the presence of Pb con- tent in game meat report lower values than ours, most likely because the area around the bullet path was avoided while sampling. The average values of total Cr were 0.141, 0.139 and 0.097 mg kg–1 w.w. in the liver, muscle and kidney, respec- tively. For Zn, the mean values were 49.76, 53.21 and 32.46 mg kg–1 w.w. in the liver, muscle and kidney, respectively. Cu content was 46.12, 12.20 and 5.64 mg Cu kg–1 w.w. in the liver, muscle and kidney, respectively. The results obtained have been validated on the basis of the scarce and inconsistent Italian literature available and on international studies

    Social-emotional skills of teachers:Mapping the content space and defining taxonomy requirements

    Get PDF
    Many studies acknowledge the importance of social-emotional skills(1) (SEMS) to function in contemporary society. Understanding these skills and how these develop presents several conceptual and methodological challenges, with emerging consensus on what kind of skills should be fostered in education. Less work, however, has considered SEMS specifically for teachers, despite the fact that they are presumed to be the primary agents to affect SEMS of students. The current article examines different conceptualizations of teacher SEMS and provides a first attempt at defining and structuring this broad conceptual space. We further propose a conceptual teacher SEMS framework that may serve as a basis of an empirical one to guide future educational research and policy-making

    Abiraterone acetate in metastatic castration-resistant prostate cancer after chemotherapy. A retrospective “Real Life” analysis of activity and safety

    Get PDF
    Abiraterone acetate (AA) is a potent, selective androge (CYP17) biosynthesis inhibitor, which showed to improve overall survival (HR = 0.646) in mCRPC patients progressing after docetaxel. In this retrospective analysis we assessed the safety and efficacy of AA in patients affected with mCRPC progressing after chemotherapy, treated in the normal clinical practice, in several Italian Oncologic Units, after the approval of the drug from the Italian Drug Agency (AIFA)

    In vitro fermentation patterns and methane production of sainfoin (Onobrychis viciifolia Scop.) hay with different condensed tannin contents.

    Get PDF
    Sainfoin (Onobrychis viciifolia Scop.) is a perennial legume recently reappraised for some positive charac- teristics leading to highly satisfactory animal perfor- mance. Sainfoin’s characteristics may be partly explained by the presence of moderate levels of condensed tannins (CTs) able to protect dietary protein from microbial degradation in the rumen. Decreased CH4 emissions have been reported for ruminants consuming CT-containing forage. The aim of this study was to evaluate the effects of CT content on the in vitro fermentation characteristics and kinetics and methane production of four samples of O. viciifolia cut at different phenological stages. Sainfoin hays and one sample of alfalfa hay were incubated at 39C in anaerobiosis using the in vitro gas production technique. The chemical composition, tannin content and fermentation charac- teristics and kinetics of sainfoin samples were signiïŹ- cantly affected by phenological stage. After 48 h, the CH4 production in sainfoin hays showed a tendency to increase with the advancement of phenological stage [from 38Æ6 to 49 Æ8 mL g )1 of degraded organic matter (OM)]. The best period to cut sainfoin for hay making is between early and late ïŹ‚owering, when the forage combines high OM digestibility, low CH4 production and more efïŹcient microbial fermentation

    Cognitive differentiation during childhood: A study on cognitive profiles of 5, 7, and 9-year-old children

    Get PDF
    No seio do debate sobre se a inteligĂȘncia Ă© mais bem definida por um fator geral ou por aptidĂ”es especĂ­ficas, ganha relevĂąncia a hipĂłtese da diferenciação cognitiva. AnĂĄlises recentes enfatizam o interesse dessa questĂŁo para a investigação e alertam para a relevĂąncia das suas implicaçÔes na ĂĄrea educativa. Este estudo analisou a possibilidade de a diferenciação das aptidĂ”es cognitivas ocorrer jĂĄ na infĂąncia e tambĂ©m o efeito moderador do Quociente de InteligĂȘncia na magnitude da relação entre as habilidades cognitivas. Aplicou-se uma bateria de provas que avaliam vĂĄrias funçÔes cognitivas a uma amostra de 231 crianças com 5, 7 e 9 anos, distribuĂ­das por trĂȘs grupos de desempenho cognitivo. Os resultados de uma anĂĄlise de clusters hierĂĄrquica e de uma anĂĄlise de variĂąncia apontam para a nĂŁo diferenciação das funçÔes cognitivas na infĂąncia. Contudo, uma anĂĄlise mais cuidadosa aponta para alguma diferenciação suportada pela heterogeneidade dos perfis cognitivos junto dos alunos com Quociente de InteligĂȘncia elevado.Within the debate about whether intelligence is best defined by a general factor or specific skills, the hypothesis of cognitive differentiation gains relevance. Recent analyses have emphasized the importance of this issue in the investigation of cognitive skills and have highlighted its implications in education. This study examined the possibility that the differentiation of cognitive abilities may occur during childhood and investigated the moderating effect of Intelligence Quotient on the magnitude of the relationship between cognitive abilities. A battery of tests for assessing cognitive function was administered to 231 children aged 5, 7, and 9 years old, who were divided into three cognitive performance groups. The results of hierarchical cluster analysis and variance analysis indicate the lack of differentiation of cognitive functions during childhood. However, a more careful analysis suggests some differentiation supported by the heterogeneity of cognitive profiles among students with high Intelligence Quotient.FCT -Fundação para a CiĂȘncia e a Tecnologia(SFRH/BD/84153/2012

    Abiraterone acetate in metastatic castration-resistant prostate cancer after chemotherapy. A retrospective analysis of progression-free (PFS) and overall survival (OS) in the “Real Life”

    Get PDF
    Background: Abiraterone acetate (AA) is a potent, selective androgen (CYP17) biosynthesis inhibitor, which showed to improve overall survival (HR = 0.646) in mCRPC patients progressing after docetaxel. In this retrospective analysis we assessed the PFS and OS safety in patients affected with mCRPC progressing after chemotherapy, treated in the normal clinical practice, in several Italian Oncologic Units
    • 

    corecore