Simulated Annealing for Location Area Planning in Cellular networks

LA planning in cellular network is useful for minimizing location management cost in GSM network. In fact, size of LA can be optimized to create a balance between the LA update rate and expected paging rate within LA. To get optimal result for LA planning in cellular network simulated annealing algorithm is used. Simulated annealing give optimal results in acceptable run-time.Comment: 7 Pages, JGraph-Hoc Journa

Utilisation of sea nodules leaching residue for adsorption of Ni(II) ions

Polymetallic sea nodules may be considered as lean grade ore of Cu, Ni & Co. After recovery of these valuable metals, a huge quantity of residue (~70% of ore body) is generated. In the present paper, investigations carried out for the application of leached sea nodule residue for the removal of Ni(II) from aqueous solution by adsorption, are described. Several parameters have been varied to study the feasibility of using residue as potential adsorbent for remediation Ni(II) contaminated water. The adsorption kinetics followed pseudo first-order equation and the rate of adsorption increased with solution temperature. Kinetics data of Ni(II) adsorption was also discussed using diffusion models of Webber-Morris and Dumwald-Wagner models. The equilibrium data was best fitted into Langmuir adsorption isotherm and the maximum adsorption capacities was found to be 15.15 mg g-1 at pH 5.5 and temperature 303 K, which decreased to 10.64 mg g-1 upon raising the solution temperature to 323 K. The activation energy for Ni(II) adsorption onto leached sea nodule residue was 9.56 kJ mol−1 indicated physical sorption. Desorption studies showed successful regeneration of adsorbent and recovery of Ni. This process can be utilised for removal and recovery of Ni from the industrial effluent

Role of hypogastric artery ligation in obstetrics and gynaecology: a 20-year study at tertiary care center, Ahmedabad, western India

Background: Hypogastric artery ligation (HAL) was first introduced by the end of the 19th century to control intractable haemorrhage from the uterus of women with advanced cervical cancer. Bilateral HAL is a lifesaving procedure in massive pelvic haemorrhage.Methods: This is a retrospective study of 58 cases in which HAL was performed in the obstetrics and gynecology department at tertiary care center from January 2000 to December 2020. History, operative procedure findings, immediate and late postoperative complications, morbidity and mortality data were collected and reviewed from records.Results: In this study, total of 58 women who underwent HAL s; 53 bilateral and 5 unilateral. Fifty-three women required HAL for obstetric indications, in 5 cases it was required for gynaecological indications. 20 cases (34.5%) underwent bilateral HAL for atonic PPH, 16 cases (27.6%) during obstetric hysterectomy for morbidly adherent placenta, 5 (8.6%) for colporrhexis, 2 (3.4%) for broad ligament hematoma, 1 (1.7%) for colporrhexis and left sided broad ligament hematoma, 2 cases (3.4%) for secondary PPH and 7 cases (12.1%) for the ruptured uterus. In gynecological cases 4 cases (80%) underwent after vaginal hysterectomy to control pelvic haemorrhage and 1 case (20%) underwent HAL after myomectomy.Conclusions: HAL is an important surgical procedure and should be performed to reduce blood loss when conservation of the uterus is desired. It is also useful in controlling haemorrhage after major gynaecological surgeries and secondary hemorrhage following hysterectomy.

Baker's Yeast-catalysed ring opening of benzofuroxans : an efficient green synthesis of aryl-1,2-diamines

A simple and inexpensive method for the reductive cleavage of N–O bond of benzofuroxans with bakers’ yeast under nonfermenting condition in aqueous media was achieved. The procedure gives excellent yields of aryl-1, 2-diamines

A study of habit of fast food eating among school going adolescents and parental advice and its relation with their nutritional status

Background:A study of habit of fast food eating among school going adolescents and parental advice and its relation with their nutritional status.Methods: Design: an epidemiological analytic observational study. Subjects: 600 adolescents’ 15-19 years of age, studying in 11 and 12 classes and included both boys and girls. A single observer interviewed each student and gathered the information regarding their eating habits. It was recorded on a pre-tested open and closed ended Performa. Nutritional status was assessed by BMI. The adolescents for the purpose of analysis were broadly grouped in two groups. Group I (those having normal BMI ranging 18.5 to 25) and group II (Malnourished i.e. those having BMI 25). Group II adolescents were further divided into group IIa (Underweight, BMI25).Results:Adolescents who took both fast food and soft drinks 73.1% were malnourished (group II) as compared to those who did not take both the things 13.7% in group II. Difference was found to be statistically significant (p value 25) subsequently. Incidence of malnutrition was significantly less in 12.4% adolescents’ interfered by their parents as compared to 69.6% of those where parents was not interfering. Difference was found to be statistically significant (P value <0.01).Conclusion: A habit of fast food eating and taking soft drink provokes malnutrition. Interference in eating by parents is beneficial among adolescents.

Syntheses, spectral characterization and antidiabetic activities of oxidovanadium(V) complexes with bi-and tridentate ligands

254-262Four new oxidovanadium(V) complexes [VO(L1)(Mol)] (1), [VO(L2)(Mol)] (2), [VO(L3)(Mol)] (3) and [VO(L4)(Mol)] (4)(where L1-L4 = aroylhydrazones and Mol = maltol) have been synthesized with different ligands. The complexes havebeen characterized using microanalysis, spectral fab mass, UV-visible, electrochemical (cyclic voltammetry and differentialpulse voltammetry), density functional theory calculations have been performed to predict the optimized geometry, globalreactivity parameters and electron density. In these complexes, the d-d absorption band is not observed as being d0 vanadiumcentres in these complexes. The electrochemical behaviour of these complexes are explored by cyclic voltammetry anddifferential pulse voltammetry (DPV). All complexes exhibit one electron transfer i.e., reduction of vanadium(V) tovanadium(IV). These complexes are screened for in vitro α-glucosidase and α-amylase inhibition study. Complex 3 has aninteresting insulin-like activity

Evaluation of antioxidative, proteolytic, and ace inhibitory activities of potential probiotic lactic acid bacteria isolated from traditional fermented food products

Probiotic lactic acid bacteria (LAB) have been engrossed in plentiful food fermentations, known to man for millennia. The current investigation was aimed at investigating technical attributes, such as production of bioactive peptides, particularly ACE-I activity (anti-hypertensive property), proteolytic activity, and antioxidant activities of the potential probiotic LAB strains isolated from a diverse dairy and non-dairy based fermented foods. Among all ten LAB isolates, PFC21, isolated from sauerkraut, exhibited the highest antioxidative potential and showed maximum free radical scavenging ability using both ABTS (83.8±3.77%) and DPPH (59.4±2.18%) assays. It was followed by PD2 (dosa batter isolate) that showed (79.4±1.61%) activity in ABTS assay. PD2 revealed the highest proteolytic activity during 24 h and 48 h (with 0.82 and 1.12 absorbance, respectively) of fermentation at 37 °C; followed by a curd isolate, PC6, and PFC21 with 0.99 and 0.90 absorbance, respectively, at 48 h incubation. Furthermore, PD2 also showed the significantly (P<0.05) highest (49.39%) ACE inhibition followed by PFC21 (41.38%). These fascinating results led us to further evaluate the potential probiotic strains with regard to their utilization in the production of healthy quality foods with additional technical advantages

Expression of expanded FMR1-CGG repeats alters mitochondrial miRNAs and modulates mitochondrial functions and cell death in cellular model of FXTAS

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a progressive neurodegenerative disorder caused by an expansion of 55 to 200 CGG repeats located within 5′UTR of FMR1.These CGG repeats are transcribed into RNAs, which sequester several RNA binding proteins and alter the processing of miRNAs. CGG repeats are also translated into a toxic polyglycine-containing protein, FMRpolyG, that affects mitochondrial and nuclear functions reported in cell and animal models and patient studies. Nuclear-encoded small non-coding RNAs, including miRNAs, are transported to mitochondria; however, the role of mitochondrial miRNAs in FXTAS pathogenesis is not understood. Here, we analyzed mitochondrial miRNAs from HEK293 cells expressing expanded CGG repeats and their implication in the regulation of mitochondrial functions. The analysis of next generation sequencing (NGS) data of small RNAs from HEK293 cells expressing CGG premutation showed decreased level of cellular miRNAs and an altered pattern of association of miRNAs with mitochondria (mito-miRs). Among such mito-miRs, miR-320a was highly enriched in mitoplast and RNA immunoprecipitation of Ago2 (Argonaute-2) followed by Droplet digital PCR (ddPCR)suggested that miR-320a may form a complex with Ago2 and mitotranscripts. Finally, transfection of miR-320a mimic in cells expressing CGG permutation recovers mitochondrial functions and rescues cell death. Overall, this work reveals an altered translocation of miRNAs to mitochondria and the role of miR-320a in FXTAS pathology