Asteroseismology, standard candles and the Hubble Constant: what is the role of asteroseismology in the era of precision cosmology?

Classical Cepheids form one of the foundations of modern cosmology and the extragalactic distance scale, however, cosmic microwave background observations measure cosmological parameters and indirectly the Hubble Constant, H0, to unparalleled precision. The coming decade will provide opportunities to measure H0 to 2% uncertainty thanks to the GAIA satellite, JWST, ELTs and other telescopes using Cepheids and other standard candles. In this work, we discuss the upcoming role for variable stars and asteroseismology in calibrating the distance scale and measuring H0 and what problems exist in understanding these stars that will feedback on these measurements.Comment: 8 pages, summary of splinter session at IAU Symposium 301, Precision Asteroseismology, August 2013, Wroclaw, Polan

Stochastic Gene Expression in Single Gene Oscillator Variants

It is infeasible to understand all dynamics in cell, but we can aim to understand the impact of design choices under our control. Here we consider a single gene oscillator as a case study to understand the influence of DNA copy number and repressor choice on the resulting dynamics. We first switch the repressor in the oscillator from the originally published lacI to treRL, a chimeric repressor with a lacI DNA binding domain that is inducible by trehalose. This slightly modified system produces faster and more regular oscillations than the original lacI oscillator. We then compare the treRL oscillator at three different DNA copy numbers. The period and amplitude of oscillations increases as the copy number is decreased. We cannot explain the change in period with differential equation models without changing delays or degradation rates. The correlation and phase coherence between daughter cells after cell division also tend to fall off faster for the lower copy oscillator variants. These results suggest that lower copy number variants of our single gene oscillator produce more synchronized oscillations

Using cellular fitness to map the structure and function of a major facilitator superfamily effluxer.

The major facilitator superfamily (MFS) effluxers are prominent mediators of antimicrobial resistance. The biochemical characterization of MFS proteins is hindered by their complex membrane environment that makes in vitro biochemical analysis challenging. Since the physicochemical properties of proteins drive the fitness of an organism, we posed the question of whether we could reverse that relationship and derive meaningful biochemical parameters for a single protein simply from fitness changes it confers under varying strengths of selection. Here, we present a physiological model that uses cellular fitness as a proxy to predict the biochemical properties of the MFS tetracycline efflux pump, TetB, and a family of single amino acid variants. We determined two lumped biochemical parameters roughly describing Km and Vmax for TetB and variants. Including in vivo protein levels into our model allowed for more specified prediction of pump parameters relating to substrate binding affinity and pumping efficiency for TetB and variants. We further demonstrated the general utility of our model by solely using fitness to assay a library of tet(B) variants and estimate their biochemical properties

Building Resistance and Resilience: Regeneration Should Not be Left to Chance

Contemporary forest planning has tasked managers with developing goals associated with resistance and resilience. In practice, silviculturists use forest structure and tree species composition to characterize goals and desired future conditions, write prescriptions, and monitor outcomes associated with resistance and resilience. Although rarely discussed in the exploding literature relating to forest resistance and resilience, silvicultural regeneration methods are important and underutilized tools to meet these goals. We propose alternative silvicultural systems for building resistance and resilience to two common large-scale bark beetle disturbance agents in the Intermountain West, United States: mountain pine beetle (Dendroctonus ponderosae Hopkins) and spruce beetle (Dendroctonus rufipennis Kirby). Shelterwood, and shelterwood-with-reserves, silvicultural systems provide the desirable facilitative characteristics of a mature overstory on maintaining advance reproduction and the establishment of new cohorts of desirable tree species. These also allow the timely regeneration of large treatment areas necessary to rapidly promote desired future conditions in the face of inevitable disturbance. When implemented proactively, regeneration treatments allow silviculturists to take advantage of currently existing vegetation for the creation of age class and tree species diversity. In general, these examples illustrate the need for proactive planning for regeneration in response to any disturbance where desired future conditions include particular species. Furthermore, we argue that timely silvicultural interventions that focus on regenerating trees may be a key factor in achieving goals relating to resilience to specific disturbance types. Waiting until after the disturbance has occurred could result in the lost opportunity to establish desired species composition or stand structure—and may well result in a considerable restoration challenge

Circles of Connection: Finding Social Connectedness and Meaning within Group Process

Social participation is an area of occupation that can increase and enhance an individual’s participation in life. This is particularly true in senior housing communities where common issues of aging and adjustment can be addressed while reducing feelings of social isolation. The purpose of this demonstration project was to provide a venue where older adults living at The Redwoods, a senior housing community in Mill Valley, California, could share and develop meaningful strategies for living, and ultimately foster a sense of connectedness, which would affect quality of life. The project’s goals were to create and implement a series of process groups to benefit the well-being of the residents of The Redwoods, and to produce a resource manual for Dominican University occupational therapy graduate students in co-facilitating the process groups. The project and manual were used as the basis for a Community Practice Lab during which the students were able to gain experience in the psychosocial occupational therapy skills for which they had been trained, while simultaneously providing the residents with an opportunity for social engagement and meaningful activity. Within the scope of occupational therapy practice, therapists can develop and facilitate psychosocial process groups that promote connectedness and well-being among residents of senior housing communities

Theoretical Models for Classical Cepheids: IV. Mean Magnitudes and Colors and the Evaluation of Distance, Reddening and Metallicity

We discuss the metallicity effect on the theoretical visual and near-infrared PL and PLC relations of classical Cepheids, as based on nonlinear, nonlocal and time--dependent convective pulsating models at varying chemical composition. In view of the two usual methods of averaging (magnitude-weighted and intensity-weighted) observed magnitudes and colors over the full pulsation cycle, we briefly discuss the differences between static and mean quantities. We show that the behavior of the synthetic mean magnitudes and colors fully reproduces the observed trend of Galactic Cepheids, supporting the validity of the model predictions. In the second part of the paper we show how the estimate of the mean reddening and true distance modulus of a galaxy from Cepheid VK photometry depend on the adopted metal content, in the sense that larger metallicities drive the host galaxy to lower extinctions and distances. Conversely, self-consistent estimates of the Cepheid mean reddening, distance and metallicity may be derived if three-filter data are taken into account. By applying the theoretical PL and PLC relations to available BVK data of Cepheids in the Magellanic Clouds we eventually obtain Z \sim 0.008, E(B-V) \sim 0.02 mag, DM \sim 18.63 mag for LMC and Z \sim 0.004, E(B-V) \sim 0.01 mag., DM \sim 19.16 mag. for SMC. The discrepancy between such reddenings and the current values based on BVI data is briefly discussed.Comment: 16 pages, 11 postscript figures, accepted for publication on Ap

Why Engagement Matters in Sport Volunteer Motivation

Over the years, sport management scholars have been interested in sport volunteer research. Considering there is a heavy reliance on sport volunteers to successfully stage of sporting events, knowing how to recruit and retain these volunteers allows sport event managers and organizers to continue this success. One such way is through understanding the engagement of sport volunteers, specifically the influences of engagement. Through survey methodology, this study examined how engagement of 464 sport volunteers at college football bowl games influenced motivational aspects. Structural Equation Modeling found that meaningfulness and safety had a significant impact on love and purposive motivation through engagement, but there was no significant relationship with rewards. With these results in mind, there are implications for sport event organizers to remember when working with volunteers. Keywords: Human resource management, volunteer engagement, volunteer motivatio