Tunneling in a Cosmological Model with Violation of Strong Energy Condition

The tunneling rate, with exact prefactor, is calculated to first order in \hbar for a closed FRW universe filled with perfect fluid violating the strong energy condition. The calculations are performed by applying the dilute-instanton approximation on the corresponding Duru-Kleinert path integral. It is shown that a closed FRW universe filled with a perfect fluid with small violation of strong energy condition is more probable to tunnel than the same universe with large violation of strong energy condition.Comment: 11 pages, LaTe

The comparison between two methods of basic life support instruction: Video self-instruction versus traditional method

Introduction: Medical education is changing and evolving. Teachers need to re-evaluate their medical teaching practice to enhance student learning. The data about the ideal training method of Basic Life Support (BLS) is lacking. The goal of this study was to analyse the use and performance of video self-instruction (VSI) method in BLS, in order to develop an efficient BLS training method. Methods: Eighty-one undergraduate medical interns were enrolled in a prospective clinical study in 2011. They were divided into VSI group and traditional group. We provided the first group with a DVD containing a 20-minute training video while the second group took part in a 4-hour training class of BLS. Subjects participated in a pre-test and post-test based on 2010 American Heart Association Resuscitation guideline. Results: The average scores of VSI group and the traditional group before training were 8.85±2.42 and 8.57±2.22 respectively (p=0.592). After training, the average scores of the VSI and the traditional group were 20.24±0.83 and 18.05±1.86 respectively. VSI group achieved slightly better scores compared with the traditional group (p<0.001). Conclusions: Training through VSI achieves more satisfying results than the traditional lecture method. VSI method can be considered a useful technique in undergraduate educational programs. Developing VSI can increase significantly the access to the BLS training. © 2015, Medcom Limited. All rights reserved

String cosmology from Poisson-Lie T-dual sigma models on supermanifolds

We generalize the formulation of Poisson-Lie T-dual sigma models on manifolds to supermanifolds. In this respect, we formulate 1+1 dimensional string cosmological models on the Lie supergroup C^3 and its dual (A_1,1 + 2A)^0_(1,0,0), which are coupled to two fermionic fields. Then, we solve the equations of motion of the models and show that there is a essential singularity for the metric of the original model and its dual.Comment: 17 pages, Appendix and three references have adde

Classification of real three-dimensional Lie bialgebras and their Poisson-Lie groups

Classical r-matrices of the three-dimensional real Lie bialgebras are obtained. In this way all three-dimensional real coboundary Lie bialgebras and their types (triangular, quasitriangular or factorizable) are classified. Then, by using the Sklyanin bracket, the Poisson structures on the related Poisson-Lie groups are obtained.Comment: 17 page

Diffeomorphism algebra of two dimensional free massless scalar field with signature change

We study a model of free massless scalar fields on a two dimensional cylinder with metric that admits a change of signature between Lorentzian and Euclidean type (ET), across the two timelike hypersurfaces (with respect to Lorentzian region). Considering a long strip-shaped region of the cylinder, denoted by an angle \theta, as the signature changed region it is shown that the energy spectrum depends on the angle \theta and in a sense differs from ordinary one for low energies. Morever diffeomorphism algebra of corresponding infinite conserved charges is different from '' Virasoro'' algebra and approaches to it at higher energies. The central term is also modified but does not approach to the ordinary one at higher energies.Comment: 18 pages, Latex, 2 ps figure

Tunneling in Λ\Lambda Decaying Cosmologies and the Cosmological Constant Problem

The tunneling rate, with exact prefactor, is calculated to first order in $\hbar$ for an empty closed Friedmann-Robertson-Walker (FRW) universe with decaying cosmological term $\Lambda \sim R^{-m}$ ($R$ is the scale factor and $m$ is a parameter $0\leq m \leq 2$). This model is equivalent to a cosmology with the equation of state $p_{\chi}=(m/3 -1)\rho_{\chi}$. The calculations are performed by applying the dilute-instanton approximation on the corresponding Duru-Kleinert path integral. It is shown that the highest tunneling rate occurs for $m=2$ corresponding to the cosmic string matter universe. The obtained most probable cosmological term, like one obtained by Strominger, accounts for a possible solution to the cosmological constant problem.Comment: 21 pages, REVTEX, The section 3 is considerably completed including some physical mechanisms supporting the time variation of the cosmological constant, added references for the section 3. Accepted to be published in Phys. Rev.

Endophthalmitis caused by Acinetobacter spp. as the presenting manifestation of diabetes mellitus

Purpose We describe a patient with endogenous endophthalmitis caused by Acinetobacter spp. as the first clinical presentation of diabetes mellitus. Method A 48-year-old otherwise healthy woman was referred with signs and symptoms of acute endophthalmitis in the left eye. Systemic work-up, vitreous tap, and intravitreal antibiotic injection were performed followed by pars plana vitrectomy. Results The laboratory tests confirmed the diagnosis of diabetes mellitus. Vitreous culture was positive for Acinetobacter spp., and the organism was sensitive to colistin. One month after surgery, vision was no light perception, and the eye was phthisical. Conclusion Diagnostic work-up should be performed even in otherwise healthy patients with endogenous endophthalmitis. © 2016 Iranian Society of Ophthalmolog

A hysteretic multiscale formulation for nonlinear dynamic analysis of composite materials

This article has been made available through the Brunel Open Access Publishing Fund.A new multiscale finite element formulation is presented for nonlinear dynamic analysis of heterogeneous structures. The proposed multiscale approach utilizes the hysteretic finite element method to model the microstructure. Using the proposed computational scheme, the micro-basis functions, that are used to map the microdisplacement components to the coarse mesh, are only evaluated once and remain constant throughout the analysis procedure. This is accomplished by treating inelasticity at the micro-elemental level through properly defined hysteretic evolution equations. Two types of imposed boundary conditions are considered for the derivation of the multiscale basis functions, namely the linear and periodic boundary conditions. The validity of the proposed formulation as well as its computational efficiency are verified through illustrative numerical experiments

Contrasting cloud composition between coupled and decoupled marine boundary layer clouds

Marine stratocumulus clouds often become decoupled from the vertical layer immediately above the ocean surface. This study contrasts cloud chemical composition between coupled and decoupled marine stratocumulus clouds for dissolved nonwater substances. Cloud water and droplet residual particle composition were measured in clouds off the California coast during three airborne experiments in July–August of separate years (Eastern Pacific Emitted Aerosol Cloud Experiment 2011, Nucleation in California Experiment 2013, and Biological and Oceanic Atmospheric Study 2015). Decoupled clouds exhibited significantly lower air-equivalent mass concentrations in both cloud water and droplet residual particles, consistent with reduced cloud droplet number concentration and subcloud aerosol (D_p > 100 nm) number concentration, owing to detachment from surface sources. Nonrefractory submicrometer aerosol measurements show that coupled clouds exhibit higher sulfate mass fractions in droplet residual particles, owing to more abundant precursor emissions from the ocean and ships. Consequently, decoupled clouds exhibited higher mass fractions of organics, nitrate, and ammonium in droplet residual particles, owing to effects of long-range transport from more distant sources. Sodium and chloride dominated in terms of air-equivalent concentration in cloud water for coupled clouds, and their mass fractions and concentrations exceeded those in decoupled clouds. Conversely, with the exception of sea-salt constituents (e.g., Cl, Na, Mg, and K), cloud water mass fractions of all species examined were higher in decoupled clouds relative to coupled clouds. Satellite and Navy Aerosol Analysis and Prediction System-based reanalysis data are compared with each other, and the airborne data to conclude that limitations in resolving boundary layer processes in a global model prevent it from accurately quantifying observed differences between coupled and decoupled cloud composition

Amorphous formulations of indomethacin and griseofulvin prepared by electrospinning

Following an array of optimization experiments, two series of electrospun polyvinylpyrrolidone (PVP) fibers were prepared. One set of fibers contained various loadings of indomethacin, known to form stable glasses, and the other griseofulvin (a poor glass former). Drug loadings of up to 33% w/w were achieved. Electron microscopy data showed the fibers largely to comprise smooth and uniform cylinders, with evidence for solvent droplets in some samples. In all cases, the drug was found to exist in the amorphous physical state in the fibers on the basis of X-ray diffraction and differential scanning calorimetry (DSC) measurements. Modulated temperature DSC showed that the relationship between a formulation’s glass transition temperature (<i>T</i>_g) and the drug loading follows the Gordon–Taylor equation, but not the Fox equation. The results of Gordon–Taylor analysis indicated that the drug/polymer interactions were stronger with indomethacin. The interactions between drug and polymer were explored in more detail using molecular modeling simulations and again found to be stronger with indomethacin; the presence of significant intermolecular forces was further confirmed using IR spectroscopy. The amorphous form of both drugs was found to be stable after storage of the fibers for 8 months in a desiccator (relative humidity <25%). Finally, the functional performance of the fibers was studied; in all cases, the drug-loaded fibers released their drug cargo very rapidly, offering accelerated dissolution over the pure drug