42 research outputs found
A new integrated power plant with a small scale turbine for the Organic Rankine Cycle
Combined heat and power (CHP or cogeneration) describes the simultaneous generation of electrical power and heat. CHP has been well established for medium and high power ranges (> 100 kW el. power). The Kompakte Dampf Turbine (KDT, meaning compact steam turbine) addresses the low-end of power generation (~2 kW el. power). The KDT is a highly integrated power plant of small dimensions able to use various heat sources. Its simple design promises a low-cost CHP for residential homes
Inter-band B(E2) transition strengths in odd-mass heavy deformed nuclei
Inter-band B(E2) transition strengths between different normal parity bands
in 163Dy and 165Er are described using the pseudo-SU(3) model. The Hamiltonian
includes Nilsson single-particle energies, quadrupole-quadrupole and pairing
interactions with fixed, parametrized strengths, and three extra rotor terms
used to fine tune the energy spectra. In addition to inter-band transitions,
the energy spectra and the ground state intra-band B(E2) strengths are
reported. The results show the pseudo-SU(3) shell model to be a powerful
microscopic theory for a description of the normal parity sector in heavy
deformed odd-A nuclei.Comment: 4 figures, 2 table
SU(3) realization of the rigid asymmetric rotor within the IBM
It is shown that the spectrum of the asymmetric rotor can be realized quantum
mechanically in terms of a system of interacting bosons. This is achieved in
the SU(3) limit of the interacting boson model by considering higher-order
interactions between the bosons. The spectrum corresponds to that of a rigid
asymmetric rotor in the limit of infinite boson number.Comment: 9 pages, 2 figures, LaTeX, epsfi
Shell model description of normal parity bands in odd-mass heavy deformed nuclei
The low-energy spectra and B(E2) electromagnetic transition strengths of
159Eu, 159Tb and 159Dy are described using the pseudo SU(3) model. Normal
parity bands are built as linear combinations of SU(3) states, which are the
direct product of SU(3) proton and neutron states with pseudo spin zero (for
even number of nucleons) and pseudo spin 1/2 (for odd number of nucleons). Each
of the many-particle states have a well-defined particle number and total
angular momentum. The Hamiltonian includes spherical Nilsson single-particle
energies, the quadrupole-quadrupole and pairing interactions, as well as three
rotor terms which are diagonal in the SU(3) basis. The pseudo SU(3) model is
shown to be a powerful tool to describe odd-mass heavy deformed nuclei.Comment: 11 pages, 2 figures, Accepted to be published in Phys. Rev.
Correlation of SHOX2 Gene Amplification and DNA Methylation in Lung Cancer Tumors
<p>Abstract</p> <p>Background</p> <p>DNA methylation in the <it>SHOX2 </it>locus was previously used to reliably detect lung cancer in a group of critical controls, including 'cytologically negative' samples with no visible tumor cell content, at a high specificity based on the analysis of bronchial lavage samples. This study aimed to investigate, if the methylation correlates with <it>SHOX2 </it>gene expression and/or copy number alterations. An amplification of the <it>SHOX2 </it>gene locus together with the observed tumor-specific hypermethylation might explain the good performance of this marker in bronchial lavage samples.</p> <p>Methods</p> <p><it>SHOX2 </it>expression, gene copy number and DNA methylation were determined in lung tumor tissues and matched morphologically normal adjacent tissues (NAT) from 55 lung cancer patients. Quantitative HeavyMethyl (HM) real-time PCR was used to detect <it>SHOX2 </it>DNA methylation levels. <it>SHOX2 </it>expression was assayed with quantitative real-time PCR, and copy numbers alterations were measured with conventional real-time PCR and array CGH.</p> <p>Results</p> <p>A hypermethylation of the <it>SHOX2 </it>locus in tumor tissue as compared to the matched NAT from the same patient was detected in 96% of tumors from a group of 55 lung cancer patients. This correlated highly significantly with the frequent occurrence of copy number amplification (p < 0.0001), while the expression of the <it>SHOX2 </it>gene showed no difference.</p> <p>Conclusions</p> <p>Frequent gene amplification correlated with hypermethylation of the <it>SHOX2 </it>gene locus. This concerted effect qualifies <it>SHOX2 </it>DNA methylation as a biomarker for lung cancer diagnosis, especially when sensitive detection is needed, i.e. in bronchial lavage or blood samples.</p
Problemes d'echantillonnage pour l'analyse chimique des boues, des sols et des plantes
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