1,915 research outputs found
Exciton-magnon effects in the optical spectrum of MnF2
Exciton and magnon absorption, emission spectra, and fluorescence of antiferromagnetic manganese fluorid
The Cleft Care UK study. Part 4:perceptual speech outcomes
OBJECTIVES: To describe the perceptual speech outcomes from the Cleft Care UK (CCUK) study and compare them to the 1998 Clinical Standards Advisory Group (CSAG) audit. SETTING AND SAMPLE POPULATION: A cross-sectional study of 248 children born with complete unilateral cleft lip and palate, between 1 April 2005 and 31 March 2007 who underwent speech assessment. MATERIALS AND METHODS: Centre-based specialist speech and language therapists (SLT) took speech audio–video recordings according to nationally agreed guidelines. Two independent listeners undertook the perceptual analysis using the CAPS-A Audit tool. Intra- and inter-rater reliability were tested. RESULTS: For each speech parameter of intelligibility/distinctiveness, hypernasality, palatal/palatalization, backed to velar/uvular, glottal, weak and nasalized consonants, and nasal realizations, there was strong evidence that speech outcomes were better in the CCUK children compared to CSAG children. The parameters which did not show improvement were nasal emission, nasal turbulence, hyponasality and lateral/lateralization. CONCLUSION: These results suggest that centralization of cleft care into high volume centres has resulted in improvements in UK speech outcomes in five-year-olds with unilateral cleft lip and palate. This may be associated with the development of a specialized workforce. Nevertheless, there still remains a group of children with significant difficulties at school entry
Characterization of liver injury, oval cell proliferation and cholangiocarcinogenesis in glutathione S-transferase A3 knockout mice
Characterization of liver injury, oval cell proliferation and cholangiocarcinogenesis in glutathione S-transferase A3 knockout mice
Kick stability in groups and dynamical systems
We consider a general construction of ``kicked systems''. Let G be a group of
measure preserving transformations of a probability space. Given its
one-parameter/cyclic subgroup (the flow), and any sequence of elements (the
kicks) we define the kicked dynamics on the space by alternately flowing with
given period, then applying a kick. Our main finding is the following stability
phenomenon: the kicked system often inherits recurrence properties of the
original flow. We present three main examples. 1) G is the torus. We show that
for generic linear flows, and any sequence of kicks, the trajectories of the
kicked system are uniformly distributed for almost all periods. 2) G is a
discrete subgroup of PSL(2,R) acting on the unit tangent bundle of a Riemann
surface. The flow is generated by a single element of G, and we take any
bounded sequence of elements of G as our kicks. We prove that the kicked system
is mixing for all sufficiently large periods if and only if the generator is of
infinite order and is not conjugate to its inverse in G. 3) G is the group of
Hamiltonian diffeomorphisms of a closed symplectic manifold. We assume that the
flow is rapidly growing in the sense of Hofer's norm, and the kicks are
bounded. We prove that for a positive proportion of the periods the kicked
system inherits a kind of energy conservation law and is thus superrecurrent.
We use tools of geometric group theory and symplectic topology.Comment: Latex, 40 pages, revised versio
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Thermal reactivity of mixtures of VDDT lubricant and simulated Hanford Tank 241-SY-101 waste
To predict whether the Polywater G lubricant residue remaining in the velocity, density, and temperature tree (VDTT) and the waste in Tank 241-SY-101 (101SY) will be chemically compatible with wastes in 101SY when two VDTTs are removed from 101SY, the Pacific Northwest National Laboratory measured the thermal reaction sensitivity of the lubricant residue. This residue is a simulated 101SY waste containing the organic surrogate trisodium hydroxyethyl-ethylenediaminetriacetate (Na{sub 3}HEDTA) and two simulated potential waste and lubricant residue mixtures containing 10 and 90 percent lubricant residue. These studies using accelerating rate calorimetry found that the residue did not react at a rate exceeding 0.1 J/min/g mixture up to 190 degrees C with simulated 101SY waste containing Na{sub 3}HEDTA as the organic surrogate. Also, the dried lubricant residue did not decompose exothermically at a rate exceeding 0.1 J/min/g. Using guidelines used by the chemical industry, these results indicate that the lubricant residue should not react as a significant rate with the waste in 101SY when added to the waste at 60 degrees C or when the mixture cools to the waste`s temperature of 48 degrees C
Ultrahigh Bandwidth Spin Noise Spectroscopy: Detection of Large g-Factor Fluctuations in Highly n-Doped GaAs
We advance all optical spin noise spectroscopy (SNS) in semiconductors to
detection bandwidths of several hundred gigahertz by employing an ingenious
scheme of pulse trains from ultrafast laser oscillators as an optical probe.
The ultrafast SNS technique avoids the need for optical pumping and enables
nearly perturbation free measurements of extremely short spin dephasing times.
We employ the technique to highly n-doped bulk GaAs where magnetic field
dependent measurements show unexpected large g-factor fluctuations.
Calculations suggest that such large g-factor fluctuations do not necessarily
result from extrinsic sample variations but are intrinsically present in every
doped semiconductor due to the stochastic nature of the dopant distribution.Comment: 5 pages, 3 figure
Ion-lithium collision dynamics studied with an in-ring MOTReMi
We present a novel experimental tool allowing for kinematically complete
studies of break-up processes of laser-cooled atoms. This apparatus, the
'MOTReMi', is a combination of a magneto-optical trap (MOT) and a Reaction
Microscope (ReMi). Operated in an ion-storage ring, the new setup enables to
study the dynamics in swift ion-atom collisions on an unprecedented level of
precision and detail. In first experiments on collisions with 1.5 MeV/amu
O-Li the pure ionization of the valence electron as well as
ionization-excitation of the lithium target has been investigated
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Epilepsy Surgery for Pharmacoresistant Temporal Lobe Epilepsy: A Decision Analysis
Context Patients with pharmacoresistant epilepsy have increased mortality compared with the general population, but patients with pharmacoresistant temporal lobe epilepsy who meet criteria for surgery and who become seizure-free after anterior temporal lobe resection have reduced excess mortality vs those with persistent seizures.
Objective To quantify the potential survival benefit of anterior temporal lobe resection for patients with pharmacoresistant temporal lobe epilepsy vs continued medical management.
Design Monte Carlo simulation model that incorporates possible surgical complications and seizure status, with 10 000 runs. The model was populated with health-related quality-of-life data obtained directly from patients and data from the medical literature. Insufficient data were available to assess gamma-knife radiosurgery or vagal nerve stimulation.
Main Outcome Measures Life expectancy and quality-adjusted life expectancy.
Results Compared with medical management, anterior temporal lobe resection for a 35-year-old patient with an epileptogenic zone identified in the anterior temporal lobe would increase survival by 5.0 years (95% CI, 2.1-9.2) with surgery preferred in 100% of the simulations. Anterior temporal lobe resection would increase quality-adjusted life expectancy by 7.5 quality-adjusted life-years (95%, CI, −0.8 to 17.4) with surgery preferred in 96.5% of the simulations, primarily due to increased years spent without disabling seizures, thereby reducing seizure-related excess mortality and improving quality of life. The results were robust to sensitivity analyses.
Conclusion The decision analysis model suggests that on average anterior temporal lobe resection should provide substantial gains in life expectancy and quality-adjusted life expectancy for surgically eligible patients with pharmacoresistant temporal lobe epilepsy compared with medical management
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