Discontinuous Transition from a Real Bound State to Virtual Bound State in a Mixed-Valence State of SmS

Golden SmS is a paramagnetic, mixed-valence system with a pseudogap. With increasing pressure across a critical pressure Pc, the system undergoes a discontinuous transition into a metallic, anti-ferromagnetically ordered state. By using a combination of thermodynamic, transport, and magnetic measurements, we show that the pseudogap results from the formation of a local bound state with spin singlet. We further argue that the transition Pc is regarded as a transition from an insulating electron-hole gas to a Kondo metal, i.e., from a spatially bound state to a Kondo virtually bound state between 4f and conduction electrons.Comment: 5 pages, 5 figure

A Conjugate Study of Mean Winds and Planetary Waves Employing Enhanced Meteor Radars at Rio Grande, Argentina (53.8degS) and Juliusruh, Germany (54.6degN)

Two meteor radars with enhanced power and sensitivity and located at closely conjugate latitudes (54.6degN and 53.8degS) are employed for inter-hemispheric comparisons of mean winds and planetary wave structures. Our study uses data from June 2008 through May 2010 during which both radars provided nearly continuous wind measurements from approx.80 to 100 km. Monthly mean winds at 53.8degS exhibit a somewhat stronger westward mean zonal jet in spring and early summer at lower altitudes and no westward monthly mean winds at higher altitudes. In contrast, westward mean winds of approx.5-10 m/s at 54.6degN extend to above 96 km during late winter and early spring each year. Equatorward monthly mean winds extend approximately from spring to fall equinox at both latitudes, with amplitudes of approx.5-10 m/s and more rapid decreases in amplitude at 54.6degN at higher altitudes. Meridional mean winds are more variable at both latitudes during fall and winter, with both poleward and equatorward monthly means indicating longer-period variability. Planetary waves seen in the 2-day mean data are episodic and variable at both sites, exhibit dominant periodicities of approx.8-10 and 16-20 days and are more confined to late fall and winter at 54.6degN. At both latitudes, planetary waves in the two period bands coincide closely in time and exhibit similar horizontal velocity covariances that are positive (negative) at 54.6degN (53.8degS) during peak planetary wave responses

Strong quasi-particle tunneling study in the paired quantum Hall states

The quasi-particle tunneling phenomena in the paired fractional quantum Hall states are studied. A single point-contact system is first considered. Because of relevancy of the quasi-particle tunneling term, the strong tunneling regime should be investigated. Using the instanton method it is shown that the strong quasi-particle tunneling regime is described as the weak electron tunneling regime effectively. Expanding to the network model the paired quantum Hall liquid to insulator transition is discussed

Anomalous tunneling conductances of a spin singlet \nu=2/3 edge states: Interplay of Zeeman splitting and Long Range Coulomb Interaction

The point contact tunneling conductance between edges of the spin singlet $\nu=2/3,\hat{K}=(3/3/0)$ quantum Hall states is studied both in the quasiparticle tunneling picture and in the electron tunneling picture. Due to the interplay of Zeeman splitting and the long range Coulomb interaction between edges of opposite chirality novel spin excitations emerge, and their effect is characterized by anomalous exponents of the charge and spin tunneling conductances in various temperature ranges. Depending on the kinds of scatterings at the point contact and the tunneling mechanism the anomalous interaction in spin sector may enhance or suppress the tunneling conductances. The effects of novel spin excitation are also relevant to the recent NMR experiments on quantum Hall edges.Comment: Revtex File, 7 pages: To be published in Physical Reviews

A Summary of the ADVANCE Trial

The publication of the U.K. Prospective Diabetes Study (UKPDS) in 1998 helped to shape the management of type 2 diabetes in recent years (1). The study demonstrated several points. First, sulfonylureas are as safe as insulin in controlling blood glucose. Second, metformin reduced cardiovascular disease in an overweight subgroup. Third, the same benefit of glycemic control in reducing microvascular disease (previously noted in type 1 diabetes) is applied equally to patients with type 2 diabetes. A separation in A1C of ∼1% in the UKPDS reduced the risk of microvascular disease (largely diabetic retinopathy) by ∼25%. This reflected the data from the Diabetes Control and Complications Trial, where a separation in A1C of 2% in intensive and standard groups led to a reduction in microvascular disease of ∼50% (2). A fourth demonstration was that there was no significant reduction in macrovascular disease but a trend toward fewer myocardial infarctions with more intensive glucose control. Fifth, using the current treatment of the time (first-generation sulfonylureas, human ultratard insulin, or metformin), it proved impossible to maintain glucose control, which tended to deteriorate throughout the study. It is now generally believed that the progressive fall in endogenous insulin production as β-cell numbers decline makes it difficult, if not impossible, to maintain tight control using standard treatment. Sixth, the UKPDS also showed that in those patients with hypertension, lowering blood pressure (BP) to moderate levels with either captopril or atenolol could reduce microvascular disease (3). In a subsequent study, the UKPDS investigators presented the rates of both micro- and macrovascular disease according to the achieved levels of A1C during the study (4). They showed a linear relationship between A1C and both groups of complications. The implication of the article was that if glycemic control could be tightened below the levels achieved in the UKPDS, then it might be possible to reduce rates, not only of microvascular complications, but also cardiovascular disease as well. The aim of the glucose arm of the Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation (ADVANCE) trial (5) was to build on the information gained by the UKPDS and to answer the question as to whether intensifying glucose control to achieve an A1C of <6.5% would provide additional benefit in reducing the risk of both micro- and macrovascular disease. ADVANCE also asked questions about BP lowering in patients with type 2 diabetes. The aims of the BP arm were to establish whether routine provision of BP-lowering therapy produced additional benefits in terms of macro- and microvascular disease, irrespective of baseline BP, and added to the benefits produced by other cardiovascular preventive therapies, including ACE inhibitors

Purification and characterization of UDP-glucose: hydroxycoumarin 7-O-glucosyltransferase, with broad substrate specificity from tobacco cultured cells

The enzyme UDP-glucose: hydroxycoumarin 7-O-glucosyltransferase (CGTase), which catalyzes the formation of scopolin from scopoletin, was purified approximately 1200-fold from a culture of 2,4-D-treated tobacco cells (Nicotiana tabacum L. cv. Bright Yellow T-13) with a yield of 7%. Purification to apparent homogeneity, as judged by SDS-PAGE, was achieved by sequential anion-exchange chromatography, hydroxyapatite chromatography, gel filtration, a second round of anion-exchange chromatography, and affinity chromatography on UDP-glucuronic acid agarose. The purified enzyme had a pH optimum of 7.5, an isoelectric point (pI) of 5.0, and a molecular mass of 49 kDa. The enzyme did not require metal cofactors for activity. Its activity was inhibited by Zn2+, Co2+ and Cu2+ ions, as well as by SH-blocking reagents. The K-m values for UDP-glucose, scopoletin and esculetin were 43, 150 and 25 mu M. respectively. A study of the initial rate of the reaction suggested that the reaction proceeded via a sequential mechanism. The purified enzyme preferred hydroxycoumarins as substrates but also exhibited significant activity with flavonoids. A database search using the amino terminus amino acid sequence of CGTase revealed strong homology to the amino acid sequences of other glucosyltransferases in plants.ArticlePlant Science. 157(1):105-112 (2000)journal articl

Theory of suppressed shot-noise at ν=2/(2p+χ)\nu=2/(2p+\chi)

We study the edge states of fractional quantum Hall liquid at bulk filling factor $\nu=2/(2p+\chi)$ with $p$ being an even integer and $\chi=\pm 1$. We describe the transition from a conductance plateau $G=\nu G_0=\nu e^2/h$ to another plateau $G=G_0/(p+\chi)$ in terms of chiral Tomonaga-Luttinger liquid theory. It is found that the fractional charge $q$ which appears in the classical shot-noise formula $S_{I}=2q$ is $q=e/(2p+\chi)$ on the conductance plateau at $G=\nu G_0$ whereas on the plateau at $G=G_0/(p+\chi)$ it is given by $q=e/(p+\chi)$. For $p=2$ and $\chi=-1$ an alternative hierarchy constructions is also discussed to explain the suppressed shot-noise experiment at bulk filling factor $\nu=2/3$.Comment: Typos in Eqs. (5-7) correcte

Theory of non-equilibrium noise in general multi-terminal superconducting hydrid devices: application to multiple Cooper pair resonances

We consider the out-of-equilibrium behavior of a general class of mesoscopic devices composed of several superconducting or/and normal metal leads separated by quantum dots. Starting from a microscopic Hamiltonian description, we provide a non-perturbative approach to quantum electronic transport in the tunneling amplitudes between dots and leads: using the equivalent of a path integral formulation, the lead degrees of freedom are integrated out in order to compute both the current and the current correlations (noise) in this class of systems, in terms of the dressed Green's function matrix of the quantum dots. In order to illustrate the efficiency of this formalism, we apply our results to the "all superconducting Cooper pair beam splitter", a device composed of three superconducting leads connected via two quantum dots, where crossed Andreev reflection operates Cooper pair splitting. Commensurate voltage differences between the three leads allow to obtain expressions for the current and noise as a function of the Keldysh Nambu Floquet dressed Green's function of the dot system. This voltage configuration allows the occurrence of non-local processes involving multiple Cooper pairs which ultimately lead to the presence of non-zero DC currents in an out-of-equilibrium situation. We investigate in details the results for the noise obtained numerically in the specific case of opposite voltages, where the transport properties are dominated by the so called "quartet processes", involving the coherent exchange of two Cooper pairs among all three superconducting terminals. We show that these processes are noiseless in the non-resonant case, and that this property is also observed for other voltage configurations. When the dots are in a resonant regime, the noise characteristics change qualitatively, with the appearance of giant Fano factors.Comment: 18 pages, 12 figure

Quasi-Particle Tunneling in Anti-Pfaffian Quantum Hall State

We study tunneling phenomena at the edge of the anti-Pfaffian quantum Hall state at the filling factor $\nu=5/2$. The edge current in a single point-contact is considered. We focus on nonlinear behavior of two-terminal conductance with the increase in negative split-gate voltage. Expecting the appearance of the intermediate conductance plateau we calculate the value of its conductance by using the renormalization group (RG) analysis. Further, we show that non-perturbative quasi-particle tunneling is effectively described as perturbative electron tunneling by the instanton method. The two-terminals conductance is written as a function of the gate voltage. The obtained results enable us to distinguish the anti-Pfaffian state from the Pfaffian state experimentally.Comment: 5 pages, 4 figure