6,903 research outputs found
Adjustable speed operation of a hydropower plant associated to an irrigation reservoir
This paper deals with the issue of adjustable speed operation (ASO) of hydropower plants. The main idea of this technique is to allow the turbine speed to change in accordance with hydraulic conditions, thus improving the overall unit efficiency. General technical aspects of ASO are further discussed with special emphasis on the energy and operational benefits that may potentially result from its application. In order to assess these benefits, annual operation of a hydropower plant associated to an irrigation reservoir has been simulated under different scenarios, with both adjustable and fixed speed. Turbine operating range proved to be wider with ASO. In addition, simulation results confirm that considerable energy gains are expected to be obtained
Multi-centre retrospective study of long-term outcomes following traumatic elbow luxation in 37 dogs
Grid-Free 2D Plasma Simulations of the Complex Interaction Between the Solar Wind and Small, Near-Earth Asteroids
We present results from a new grid-free 2D plasma simulation code applied to a small, unmagnetized body immersed in the streaming solar wind plasma. The body was purposely modeled as an irregular shape in order to examine photoemission and solar wind plasma flow in high detail on the dayside, night-side, terminator and surface-depressed 'pocket' regions. Our objective is to examine the overall morphology of the various plasma interaction regions that form around a small body like a small near-Earth asteroid (NEA). We find that the object obstructs the solar wind flow and creates a trailing wake region downstream, which involves the interplay between surface charging and ambipolar plasma expansion. Photoemission is modeled as a steady outflow of electrons from illuminated portions of the surface, and under direct illumination the surface forms a non-monotonic or ''double-sheath'' electric potential upstream of the body, which is important for understanding trajectories and equilibria of lofted dust grains in the presence of a complex asteroid geometry. The largest electric fields are found at the terminators, where ambipolar plasma expansion in the body-sized night-side wake merges seamlessly with the thin photoelectric sheath on the dayside. The pocket regions are found to be especially complex, with nearby sunlit regions of positive potential electrically connected to unlit negative potentials and forming adjacent natural electric dipoles. For objects near the surface, we find electrical dissipation times (through collection of local environmental solar wind currents) that vary over at least 5 orders of magnitude: from 39 Micro(s) inside the near-surface photoelectron cloud under direct sunlight to less than 1 s inside the particle-depleted night-side wake and shadowed pocket region
Disrupted Lipid Metabolism in Multiple Sclerosis: A Role for Liver X Receptors?
Multiple sclerosis (MS) is a chronic neurological disease driven by autoimmune, inflammatory and neurodegenerative processes leading to neuronal demyelination and subsequent degeneration. Systemic lipid metabolism is disturbed in people with MS, and lipid metabolic pathways are crucial to the protective process of remyelination. The lipid-activated transcription factors liver X receptors (LXRs) are important integrators of lipid metabolism and immunity. Consequently, there is a strong interest in targeting these receptors in a number of metabolic and inflammatory diseases, including MS. We have reviewed the evidence for involvement of LXR-driven lipid metabolism in the dysfunction of peripheral and brain-resident immune cells in MS, focusing on human studies, both the relapsing remitting and progressive phases of the disease are discussed. Finally, we discuss the therapeutic potential of modulating the activity of these receptors with existing pharmacological agents and highlight important areas of future research
Ion Trap Mass Spectrometers for Identity, Abundance and Behavior of Volatiles on the Moon
NASA GSFC and The Open University (UK) are collaborating to deploy an Ion Trap Mass Spectrometer on the Moon to investigate the lunar water cycle. The ITMS is flight-proven throughthe Rosetta Philae comet lander mission. It is also being developed under ESA funding to analyse samples drilled from beneath the lunar surface on the Roscosmos Luna-27 lander (2025).Now, GSFC and OU will now develop a compact ITMS instrument to study the near-surface lunar exosphere on board a CLPS Astrobotic lander at Lacus Mortis in 2021
Behavioral, Cognitive, and Socioemotional Pathways from Early Childhood Adversity to BMI: Evidence from Two Prospective, Longitudinal Studies
Childhood adversity is associated with higher adult weight, but few investigations prospectively test mechanisms accounting for this association. Using two socioeconomically high-risk prospective longitudinal investigations, the Minnesota Longitudinal Study of Risk and Adaptation (MLSRA; N = 267; 45.3% female) and the Fragile Families and Child Wellbeing Study (FFCWS; n = 2,587; 48.5% female), pathways between childhood adversity and later body mass index (BMI) were tested using impulsivity, emotion dysregulation, and overeating as mediators. Childhood adversity from 0 to 5 years included four types of adversities: greater unpredictability, threat/abuse, deprivation/neglect, and low socioeconomic status. Parents reported on child impulsivity, emotion dysregulation, and overeating. Height and weight were self-reported and measured at 32 and 37 years in MLSRA and at 15 years in FFCWS. FFCWS results indicated that threat, deprivation, and low socioeconomic status predicted greater impulsivity and emotion dysregulation at 5 years, which in turn predicted greater overeating at 9 years and higher BMI z-score at 15 years. Early unpredictability in FFCWS predicted higher BMI through greater impulsivity but not emotion dysregulation at age 5. MLSRA regression results replicated the threat/abuse → emotion dysregulation → overeating → higher BMI pathway. These findings suggest that different dimensions of early adversity may follow both similar and unique pathways to predict BMI
Correlated Optical/X-ray Long-term Variability in LMXB 4U1636-536
We have conducted a 3-month program of simultaneous optical, soft and hard
X-ray monitoring of the LMXB 4U1636-536/V801 Ara using the SMARTS 1.3m
telescope and archival RXTE/ASM and Swift/XRT data. 4U1636-536 has been
exhibiting a large amplitude, quasi-periodic variability since 2002 when its
X-ray flux dramatically declined by roughly an order of magnitude. We confirmed
that the anti-correlation between soft (2-12 keV) and hard (> 20 keV) X-rays,
first investigated by Shih et al. (2005), is not an isolated event but a
fundamental characteristic of this source's variability properties. However,
the variability itself is neither strictly stable nor changing on an even
longer characteristic timescale. We also demonstrate that the optical
counterpart varies on the same timescale, and is correlated with the soft, and
not the hard, X-rays. This clearly shows that X-ray reprocessing in LMXB discs
is mainly driven by soft X-rays. The X-ray spectra in different epochs of the
variability revealed a change of spectral characteristics which resemble the
state change of black hole X-ray binaries. All the evidence suggests that
4U1636-536 is frequently (~monthly) undergoing X-ray state transitions, a
characteristic feature of X-ray novae with their wide range of luminosities
associated with outburst events. In its current behavioural mode, this makes
4U1636-536 an ideal target for investigating the details of state changes in
luminous X-ray binaries.Comment: 7 pages, 6 figures, accepted for publication in MNRA
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