Reading Disorders

There are two major types of reading disorder; developmental dyslexia and reading comprehension impairment. The primary difficulty in dyslexia is with the accurate and fluent reading of single words, whilst in reading comprehension impairment words can be read accurately but there is no or little understanding of what is read. Using the causal modelling framework, the underlying causes of the two disorders are reviewed together with the co-occurrence of reading and language disorders. The rationale for viewing reading as a dimensional disorder, where the difficulties experienced are on a continuum rather than using cut-off points to identify disorders is also reviewed

Preliminary results of the Mariner IV radio occultation measurements of the upper atmosphere of Mars

Mariner IV radio occultation measurements of Mars upper atmospher

Preliminary results of the Mariner IV OCCULATION measurement of the atmosphere of Mars

Mariner IV radio occultation measurement of Mars atmospher

Nature, Causes and Correction of Discoloration of Canned Blackeye and Purple Hull Peas.

23 p

In the Interests of clients or commerce? Legal aid, supply, demand, and 'ethical indeterminacy' in criminal defence work

As a professional, a lawyer's first duty is to serve the client's best interests, before simple monetary gain. In criminal defence work, this duty has been questioned in the debate about the causes of growth in legal aid spending: is it driven by lawyers (suppliers) inducing unnecessary demand for their services or are they merely responding to increased demand? Research reported here found clear evidence of a change in the handling of cases in response to new payment structures, though in ways unexpected by the policy's proponents. The paper develops the concept of 'ethical indeterminacy' as a way of understanding how defence lawyers seek to reconcile the interests of commerce and clients. Ethical indeterminacy suggests that where different courses of action could each be said to benefit the client, the lawyer will tend to advise the client to decide in the lawyer's own interests. Ethical indeterminacy is mediated by a range of competing conceptions of 'quality' and 'need'. The paper goes on to question the very distinction between 'supply' and 'demand' in the provision of legal services

The Politics of Commerce : The Congress of Chambers of Commerce of the Empire, 1886-1914

Peer reviewedPublisher PD

Universality of the critical conductance distribution in various dimensions

We study numerically the metal - insulator transition in the Anderson model on various lattices with dimension $2 < d \le 4$ (bifractals and Euclidian lattices). The critical exponent $\nu$ and the critical conductance distribution are calculated. We confirm that $\nu$ depends only on the {\it spectral} dimension. The other parameters - critical disorder, critical conductance distribution and conductance cummulants - depend also on lattice topology. Thus only qualitative comparison with theoretical formulae for dimension dependence of the cummulants is possible

Tissue Doppler echocardiographic quantification. Comparison to coronary angiography results in Acute Coronary Syndrome patients

BACKGROUND: Multiples indices have been described using tissue Doppler imaging (DTI) capabilities. The aim of this study was to assess the capability of one or several regional DTI parameters in separating control from ischemic myocardium. METHODS: Twenty-eight patients with acute myocardial infarction were imaged within 24-hour following an emergent coronary angioplasty. Seventeen controls without any coronary artery or myocardial disease were also explored. Global and regional left ventricular functions were assessed. High frame rate color DTI cineloop recordings were made in apical 4 and 2-chamber for subsequent analysis. Peak velocity during isovolumic contraction time (IVC), ejection time, isovolumic relaxation (IVR) and filling time were measured at the mitral annulus and the basal, mid and apical segments of each of the walls studied as well as peak systolic displacement and peak of strain. RESULTS: DTI-analysis enabled us to discriminate between the 3 populations (controls, inferior and anterior AMI). Even in non-ischemic segments, velocities and displacements were reduced in the 2 AMI populations. Peak systolic displacement was the best parameter to discriminate controls from AMI groups (wall by wall, p was systematically < 0.01). The combination IVC + and IVR< 1 discriminated ischemic from non-ischemic segments with 82% sensitivity and 85% specificity. CONCLUSION: DTI-analysis appears to be valuable in ischemic heart disease assessment. Its clinical impact remains to be established. However this simple index might really help in intensive care unit routine practice

Impact of Vaccination and Pathogen Exposure Dosage on Shedding Kinetics of Infectious Hematopoietic Necrosis Virus (IHNV) in Rainbow Trout

Vaccine efficacy in preventing clinical disease has been well characterized. However, vaccine impacts on transmission under diversefied conditions, such as variable pathogen exposure dosages, are not fully understood. We evaluated the impacts of vaccination on disease-induced host mortality and shedding of infectious hematopoietic necrosis virus (IHNV) in Rainbow Trout Oncorhynchus mykiss. Fish, in up to three different genetic lines, were exposed to different dosages of IHNV to simulate field variability. Mortality and viral shedding of each individual fish were quantified over the course of infection. As the exposure dosage increased, mortality, number offish shedding virus,daily virus quantity shed, and total amount of virus shed also increased. Vaccination significantly reduced mortality but had a much smaller impact on shedding, such that vaccinated fish still shed significant amounts of virus, particularly at higher viral exposure dosages. These studies demonstrate that the consideration of pathogen exposure dosage and transmission are critical for robust inference of vaccine efficacy