Kecenderungan Kecanduan Gim Daring Dan Konformitas Kelompok Gim Daring Pada Remaja

Pada umumnya remaja senang berorientasi pada teman sebaya atau kelompoknya sertamembutuhkan pengakuan dari kelompoknya. Perilaku konformitas mudah dijumpai di dalampergaulan maupun permainan, salah satunya adalah kebersamaan dalam bermain gim daring.Tujuan dari penelitian ini adalah menguji hubungan antara kecenderungan kecanduan gimdaring dengan konformitas terhadap kelompok gim daring pada remaja. Partisipan dalampenelitian ini adalah remaja laki-laki dan perempuan, berusia 11-21 tahun, tingkat pendidikanSekolah Menengah Pertama (SMP) hingga Perguruan Tinggi, belum menikah, diduga memilikikecenderungan kecanduan gim daring, serta yang berdomisili di Bekasi sebanyak 67 orang.Metode pengambilan sampel yang digunakan dalam penelitian ini adalah sampling purposif.Pengumpulan data dalam penelitian ini diperoleh dari Skala Konformitas serta SkalaKecanduan Gim Daring berbentuk skala Likert. Teknik analisis data yang akan digunakan padapenelitian ini adalah analisis korelasi product moment. Berdasarkan analisis data diperolehskor korelasi sebesar 0.428 (p < .00). Hasil tersebut menunjukkan bahwa terdapat hubunganpositif yang signifikan antara kecenderungan kecanduan gim daring dengan konformitasterhadap kelompok gim daring pada remaja. Hal ini berarti bahwa semakin tinggikecenderungan kecanduan gim daring maka semakin tinggi pula konformitas terhadap kelompokgim daring tersebut

On Edge Dominating Number of Tensor Product of Cycle and Path

A subset S' of E(G) is called an edge dominating set ofG if every edge not in S' is adjacent to some edge in S'. The edge dominatingnumber of G, denoted by γ'(G), of G is the minimum cardinality takenover all edge dominating sets of G. Let G1 (V1, E1) and G2(V2,E2) betwo connected graph. The tensor product of G1 and G2, denoted byG1⨂▒G2 is a graph with the cardinality of vertex |V| = |V1| × |V2|and two vertices (u1,u2) and (v1,v2) in V are adjacent in G1⨂▒G2ifu1 v1 ∈ E1 and u2,v2 ∈E2 . In this paper we study an edge dominatingnumber in the tensor product of path and cycle. The results show thatγ'(Cn⨂▒P2) = ⌈2n/3⌉ for n is odd, γ'(Cn⨂▒P3) = n for n is odd, and theedge dominating number is undefined if n is even. For n ∈even number,we investigated the edge dominating number of its component on tensorproduct of cycle Cn and path. The results are γ'c(Cn⨂▒P2)= ⌈n/3⌉ andγ'c(Cn ⨂▒P3) = ⌈n/2⌉ which Cn ,P2 and P3, respectively, is Cycle order n,Path order 2 and Path order 3

The Tree Inclusion Problem: In Linear Space and Faster

Given two rooted, ordered, and labeled trees $P$ and $T$ the tree inclusion problem is to determine if $P$ can be obtained from $T$ by deleting nodes in $T$. This problem has recently been recognized as an important query primitive in XML databases. Kilpel\"ainen and Mannila [\emph{SIAM J. Comput. 1995}] presented the first polynomial time algorithm using quadratic time and space. Since then several improved results have been obtained for special cases when $P$ and $T$ have a small number of leaves or small depth. However, in the worst case these algorithms still use quadratic time and space. Let $n_S$, $l_S$, and $d_S$ denote the number of nodes, the number of leaves, and the %maximum depth of a tree $S \in \{P, T\}$. In this paper we show that the tree inclusion problem can be solved in space $O(n_T)$ and time: O(\min(l_Pn_T, l_Pl_T\log \log n_T + n_T, \frac{n_Pn_T}{\log n_T} + n_{T}\log n_{T})). This improves or matches the best known time complexities while using only linear space instead of quadratic. This is particularly important in practical applications, such as XML databases, where the space is likely to be a bottleneck.Comment: Minor updates from last tim

Structure-guided design and optimization of small molecules targeting the protein-protein interaction between the von hippel-lindau (VHL) E3 ubiquitin ligase and the hypoxia inducible factor (HIF) alpha subunit with in vitro nanomolar affinities

E3 ubiquitin ligases are attractive targets in the ubiquitin-proteasome system, however, the development of small-molecule ligands has been rewarded with limited success. The von Hippel-Lindau protein (pVHL) is the substrate recognition subunit of the VHL E3 ligase that targets HIF-1α for degradation. We recently reported inhibitors of the pVHL:HIF-1α interaction, however they exhibited moderate potency. Herein, we report the design and optimization, guided by X-ray crystal structures, of a ligand series with nanomolar binding affinities

Pola Gaya Hidup dalam Keuangan Keluarga (Studi Kasus:unit Kerja Institusi Pendidikan Swasta di Bandung)

This research was conducted to discover lifestyle patterns in family finances. This research was conducted in a private educational institution in Bandung. Data collection technique used in this research is survey technique with questionnaires and the data analysis technique that used in this study is descriptive analysis. It has been found that the lifestyle patterns of employees at one of private educational institution in Bandung generally still have a good patterns. This is proved by the monetary sequences of their revenues and expenses. Also, the priority selection of their needs and wants in fulfilling their life style is still in control. From this research, it is known generally the respondents already have their own house, vehicles, and mobile communication devices like hand phone. The purchasing frequency of hand phone in average is less than 2 times per year. Moreover, the respondents have already had a habit of saving/investing and buying insurance. To fill their spare time, respondents prefer to gather with their family, go to mall with frequency of 1-4 times per month and do exercise. But, the problem that needs to be taken care of is how to handle their credit cards/loans because a lot of respondents have routine spending of paying credit card installment/loans. From this research, it is also found that there is still a lack of awareness for making simple bookkeeping of their revenues and expenses. Therefore to make them family finances literate, they need to follow a counseling and training on family finances. Even, they are suggested to follow the counseling and training with their family members

Pola Gaya Hidup dalam Keuangan Keluarga (Studi Kasus:unit Kerja Institusi Pendidikan Swasta di Bandung)

This research was conducted to determine lifestyle patterns in family finances. This research was conducted in a private educational institution in Bandung. Data collection technique used in this research is survey technique with questionnaires and for data analysis technique that used in this study is descriptive analysis. It has been found that the lifestyle patterns of employees at one of private educational institution in Bandung generally still have a good patterns.This is proved by the monetary sequences of their revenue and expense. Also, the priority selection of their needs and wants in fullfilling their life style is still in control.The result of this research, generally the respondents already have their own house, vehicles, and mobile communication devices like handphone, with purchasing frequency in 1 year mostly less than 2 times.Moreover, the respondents also already have a habit of saving/investing and insurance.T o fill their spare time, respondents prefer to gather with their family, go to mall with frequency in a month 1-4 times and also they do exercise. But, the problem that needs to be taken care of is how to handle their credit card/loans because a lot of respondents have routine spending of paying credit card installment/loans.From this research, also found that there is still a lack of awareness for making simple bookkeeping of their revenue and expense. Therefore to make them literate family finances, they need to follow a counseling and training about family finances. Even, they are suggested to follow the counseling and training with their family members

Pola Gaya Hidup dalam Keuangan Keluarga (Studi Kasus:unit Kerja Institusi Pendidikan Swasta di Bandung)

This research was conducted to determine lifestyle patterns in family finances. This research was conducted in a private educational institution in Bandung. Data collection technique used in this research is survey technique with questionnaires and for data analysis technique that used in this study is descriptive analysis. It has been found that the lifestyle patterns of employees at one of private educational institution in Bandung generally still have a good patterns.This is proved by the monetary sequences of their revenue and expense. Also, the priority selection of their needs and wants in fullfilling their life style is still in control.The result of this research, generally the respondents already have their own house, vehicles, and mobile communication devices like handphone, with purchasing frequency in 1 year mostly less than 2 times.Moreover, the respondents also already have a habit of saving/investing and insurance.T o fill their spare time, respondents prefer to gather with their family, go to mall with frequency in a month 1-4 times and also they do exercise. But, the problem that needs to be taken care of is how to handle their credit card/loans because a lot of respondents have routine spending of paying credit card installment/loans.From this research, also found that there is still a lack of awareness for making simple bookkeeping of their revenue and expense. Therefore to make them literate family finances, they need to follow a counseling and training about family finances. Even, they are suggested to follow the counseling and training with their family members

Bar Evolution Over the Last Eight Billion Years: A Constant Fraction of Strong Bars in GEMS

One third of present-day spirals host optically visible strong bars that drive their dynamical evolution. However, the fundamental question of how bars evolve over cosmological times has yet to be addressed, and even the frequency of bars at intermediate redshifts remains controversial. We investigate the frequency of bars out to z~1.0 drawing on a sample of 1590 galaxies from the GEMS survey, which provides morphologies from HST ACS two-color images, and highly accurate redshifts from the COMBO-17 survey. We identify spiral galaxies using the Sersic index, concentration parameter, and rest-frame color. We characterize bars and disks by fitting ellipses to F606W and F850LP images, taking advantage of the two bands to minimize bandpass shifting. We exclude highly inclined (i>60 deg) galaxies to ensure reliable morphological classifications, and apply completeness cuts of M_v <= -19.3 and -20.6. More than 40% of the bars that we detect have semi major axes a<0.5" and would be easily missed in earlier surveys without the small PSF of ACS. The bars that we can reliably detect are fairly strong (with ellipticities e>=0.4) and have a in the range ~1.2-13 kpc. We find that the optical fraction of such strong bars remains at ~(30% +- 6%) from the present-day out to look-back times of 2-6 Gyr (z~0.2-0.7) and 6-8 Gyr (z~0.7-1.0); it certainly shows no sign of a drastic decline at z>0.7. Our findings of a large and similar bar fraction at these three epochs favor scenarios in which cold gravitationally unstable disks are already in place by z~1, and where on average bars have a long lifetime (well above 2 Gyr). The distributions of structural bar properties in the two slices are, however, not statistically identical and therefore allow for the possibility that the bar strengths and sizes may evolve over time.Comment: Accepted by ApJ Letters, to appear in Nov 2004 issue. Minor revisions,updated reference

Sterol 14α-Demethylase as a Potential Target for Antitrypanosomal Therapy: Enzyme Inhibition and Parasite Cell Growth

SummarySterol 14α-demethylases (CYP51) serve as primary targets for antifungal drugs, and specific inhibition of CYP51s in protozoan parasites Trypanosoma brucei (TB) and Trypanosoma cruzi (TC) might provide an effective treatment strategy for human trypanosomiases. Primary inhibitor selection is based initially on the cytochrome P450 spectral response to ligand binding. Ligands that demonstrate strongest binding parameters were examined as inhibitors of reconstituted TB and TC CYP51 activity in vitro. Direct correlation between potency of the compounds as CYP51 inhibitors and their antiparasitic effect in TB and TC cells implies essential requirements for endogenous sterol production in both trypanosomes and suggests a lead structure with a defined region most promising for further modifications. The approach developed here can be used for further large-scale search for new CYP51 inhibitors