A colour-excess extinction map of the southern Galactic disc from the VVV and GLIMPSE surveys

An improved high-resolution and deep A Ks foreground dust extinction map is presented for the Galactic disc area within 295◦ ≾ l ≾ 350◦, −1.0◦ ≾ b ≾ +1.0◦. At some longitudes the map reaches up to |b| ~ 2.25◦, for a total of ~148 deg 2. The map was constructed via the Rayleigh–Jeans colour excess (RJCE) technique based on deep near-infrared (NIR) and mid-infrared (MIR) photometry. The new extinction map features a maximum bin size of 1 arcmin, and relies on NIR observations from the Two Micron All-Sky Survey (2MASS) and new data from ESO’s Vista Variables in the Vía Láctea (VVV) survey, in concert with MIR observations from the Galactic Legacy Infrared Mid-Plane Survey Extraordinaire. The VVV photometry penetrates ~4 mag fainter than 2MASS, and provides enhanced sampling of the underlying stellar populations in this heavily obscured region. Consequently, the new results supersede existing RJCE maps tied solely to brighter photometry, revealing a systematic underestimation of extinction in prior work that was based on shallower data. The new high-resolution and large-scale extinction map presented here is readily available to the community through a web query interface.Peer reviewe

AGN candidates in the VVV near-IR galaxy catalogue

© 2023 The Author(s). Published by Oxford University Press on behalf of Royal Astronomical Society. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1093/mnras/stad490The goal of this work is to search for Active Galactic Nuclei (AGN) in the Galactic disc at very low latitudes with |b|< 2°. For this, we studied the five sources from the VVV near-infrared (IR) galaxy catalogue that have also WISE counterparts and present variability in the VIrac VAriable Classification Ensemble (VIVACE) catalogue. In the near-IR colour-colour diagrams, these objects have in general redder colours compared to the rest of the sources in the field. In the mid-IR ones, they are located in the AGN region, however, there is a source that presents the highest interstellar extinction and different mid-IR colours to be a young stellar object (YSO). We also studied the source variability using two different statistical methods. The fractional variability amplitude σrms ranges from 12.6 to 33.8, being in concordance with previous results found for type-1 AGNs. The slopes of the light curves are in the range (2.6 - 4.7) × 10-4 mag d-1, also in agreement with results reported on quasars variability. The combination of all these results suggest that four galaxies are type-1 AGN candidates, whereas the fifth source likely a YSO candidate.Peer reviewe

The First Galaxy Cluster Discovered by the VISTA Variables in the Vía Láctea Survey

We report the first confirmed detection of the galaxy cluster VVV-J144321-611754 at very low latitudes (l = 315.°836, b = -1.°650) located in the tile d015 of the VISTA Variables in the Vía Láctea (VVV) survey. We defined the region of 30 ×30 arcmin 2 centered in the brightest galaxy finding 25 galaxies. For these objects, extinction-corrected median colors of (H-K s ) = 0.34 ± 0.05 mag, (J-H) = 0.57 ± 0.08 mag, and (J-K s ) = 0.87 ± 0.06 mag; R 1/2 = 1.59 ± 0.″16; C = 3.01 ± 0.08; and Sérsic index n = 4.63 ± 0.39 were estimated. They were visually confirmed showing characteristics of early-type galaxies in the near-IR images. An automatic clustering analysis performed in the whole tile found that the concentration of galaxies VVV-J144321-611754 is a real, compact concentration of early-type galaxies. Assuming a typical galaxy cluster with low X-ray luminosity, the photometric redshift of the brightest galaxy is z = 0.196 ± 0.025. Follow-up near-IR spectroscopy with FLAMINGOS-2 at the Gemini-South telescope revealed that the two brighter cluster galaxies have typical spectra of early-type galaxies and the estimated redshift for the brightest galaxy VVV-J144321.06-611753.9 is z = 0.234 ± 0.022 and that for VVV-J144319.02-611746.1 is z = 0.232 ± 0.019. Finally, these galaxies clearly follow the cluster red sequence in the rest-frame near-IR color-magnitude diagram with a slope similar to a galaxy cluster at a redshift of 0.2. These results are consistent with the presence of a bona fide galaxy cluster beyond the Milky Way disk.Fil: Baravalle, Laura Daniela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Nilo Castellón, José Luis. Universidad de La Serena; ChileFil: Alonso, Maria Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Díaz Tello, J.. Pontificia Universidad Católica de Chile; Chile. Universidad Nacional Autónoma de México; MéxicoFil: Damke, G.. Universidad de La Serena; ChileFil: Valotto, Carlos Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Cuevas Larenas, H.. Universidad de La Serena; ChileFil: Sánchez, Bruno Orlando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Ríos, M. de los. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Minniti, D.. Universidad Andrés Bello; ChileFil: Domínguez, M.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Gurovich, Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Barbá, R.. Universidad de La Serena; ChileFil: Soto, M.. Universidad de Atacama; ChileFil: Castro, F. Milla. Universidad de La Serena; Chil

Differential, Phosphorylation Dependent Trafficking of AQP2 in LLC-PK1 Cells

The kidney maintains water homeostasis by modulating aquaporin 2 (AQP2) on the plasma membrane of collecting duct principal cells in response to vasopressin (VP). VP mediated phosphorylation of AQP2 at serine 256 is critical for this effect. However, the role of phosphorylation of other serine residues in the AQP2 C-terminus is less well understood. Here, we examined the effect of phosphorylation of S256, S261 and S269 on AQP2 trafficking and association with recycling pathway markers. We used LLC-PK1 cells expressing AQP2(S-D) or (S-A) phospho mutants and a 20°C cold block, which allows endocytosis to continue, but prevents protein exit from the trans Golgi network (TGN), inducing formation of a perinuclear AQP2 patch. AQP2-S256D persists on the plasma membrane during cold block, while wild type AQP2, AQP2-S256A, S261A, S269A and S269D are internalized and accumulate in the patch. Development of this patch, a measure of AQP2 internalization, was most rapid with AQP2-S256A, and slowest with S261A and S269D. AQP2-S269D exhibited a biphasic internalization profile with a significant amount not internalized until 150 minutes of cold block. After rewarming to 37°C, wt AQP2, AQP2-S261A and AQP2-S269D rapidly redistributed throughout the cytoplasm within 20 minutes, whereas AQP2-S256A dissipated more slowly. Colocalization of AQP2 mutants with several key vesicular markers including clathrin, HSP70/HSC70, EEA, GM130 and Rab11 revealed no major differences. Overall, our data provide evidence supporting the role of S256 and S269 in the maintenance of AQP2 at the cell surface and reveal the dynamics of internalization and recycling of differentially phosphorylated AQP2 in cell culture

A colour-excess extinction map of the southern Galactic disc from the VVV and GLIMPSE surveys

Published versionAn improved high-resolution and deep AKs foreground dust extinction map is presented for the Galactic disc area within 295&deg; ≲ l ≲ 350&deg;, &minus;1.0&deg; ≲ b ≲ +1.0&deg;. At some longitudes the map reaches up to |b| &sim; 2.25&deg;, for a total of &sim;148&thinsp;deg2. The map was constructed via the Rayleigh&ndash;Jeans colour excess (RJCE) technique based on deep near-infrared (NIR) and mid-infrared (MIR) photometry. The new extinction map features a maximum bin size of 1', and relies on NIR observations from the Two Micron All-Sky Survey (2MASS) and new data from ESO&rsquo;s Vista Variables in the V&iacute;a L&aacute;ctea (VVV) survey, in concert with MIR observations from the Galactic Legacy Infrared Mid-Plane Survey Extraordinaire. The VVV photometry penetrates &sim;4&thinsp;mag fainter than 2MASS, and provides enhanced sampling of the underlying stellar populations in this heavily obscured region. Consequently, the new results supersede existing RJCE maps tied solely to brighter photometry, revealing a systematic underestimation of extinction in prior work that was based on shallower data. The new high-resolution and large-scale extinction map presented here is readily available to the community through a web query interface

Insights into Minor Group Rhinovirus Uncoating: The X-ray Structure of the HRV2 Empty Capsid

Upon attachment to their respective receptor, human rhinoviruses (HRVs) are internalized into the host cell via different pathways but undergo similar structural changes. This ultimately results in the delivery of the viral RNA into the cytoplasm for replication. To improve our understanding of the conformational modifications associated with the release of the viral genome, we have determined the X-ray structure at 3.0 Å resolution of the end-stage of HRV2 uncoating, the empty capsid. The structure shows important conformational changes in the capsid protomer. In particular, a hinge movement around the hydrophobic pocket of VP1 allows a coordinated shift of VP2 and VP3. This overall displacement forces a reorganization of the inter-protomer interfaces, resulting in a particle expansion and in the opening of new channels in the capsid core. These new breaches in the capsid, opening one at the base of the canyon and the second at the particle two-fold axes, might act as gates for the externalization of the VP1 N-terminus and the extrusion of the viral RNA, respectively. The structural comparison between native and empty HRV2 particles unveils a number of pH-sensitive amino acid residues, conserved in rhinoviruses, which participate in the structural rearrangements involved in the uncoating process

A deep near-infrared view of the Ophiuchus galaxy cluster

Context: The Ophiuchus cluster of galaxies, located at low latitudes in the direction of the Galactic bulge, has been relatively poorly studied in comparison with other rich galaxy clusters like Coma, Virgo and Fornax, in spite of being the 2nd brightest X-ray cluster in the sky. Methods: Deep near-infrared images and photometry from the VISTA Variables in the V\'ia L\'actea eXtended survey (VVVX) were used to detect galaxy member candidates of Ophiuchus cluster up to 2 Mpc from the cD galaxy 2MASX J17122774-2322108 using the Galdeano et al. criteria to select the galaxies among the foreground sources. We also perform a morphological visual classification, color-magnitude diagram and density profiles. Results: We identified 537 candidate galaxy members of the Ophiuchus cluster up to 2 Mpc from the cD galaxy, increasing 7 times the number of galaxies reported in previous catalogs. In addition, we performed a morphological classification of these galaxy candidates finding that the fraction of Ellipticals reaches more than the 60% in the central region of the cluster. On the other hand the Spirals fraction is lower than the 20% remaining almost constant throughout the cluster. Moreover, we study the red sequence of galaxy member candidates and use mock catalogs to explore the density profile of the cluster, finding that the value derived from the mock catalog towards an overdense region is in agreement with the galaxy excess of the central zone of the Ophiuchus cluster. Conclusions: Our investigation of the hidden population of Ophiuchus galaxies underscores the importance of this cluster as a prime target for future photometric and spectroscopic studies. Moreover the results of this work highlights the potential of VVVX survey to study extragalactic objects in the Zone of Avoidance.Comment: 8 pages, 4 figures, 1 appendi