Facts and fiction about long-term survival in tardigrades

Tardigrades have achieved a widespread reputation for an ability to survive more than a century in an inactive, ametabolic state called cryptobiosis, However, a closer look at the empirical evidence provides little support for the claim that tardigrades are capable of century-long survival. Instead, current evidence suggests that a decade may more realistically represent the upper limit of cryptobiotic survival in the most resistant tardigrades

Levantamento pedológico semidetalhado (1:25.000) da microbacia da Água Três Unidos, Município de Vera Cruz (SP).

Este trabalho é um relato dos solos identificados no levantamento pedológico semidetalhado da microbacia da Água Três Unidos. Abrangendo aproximadamente 1.624 hectares, a microbacia situa-se no município de Vera Cruz, localizada a oeste do Estado de São Paulo, entre as coordenadas geográficas 22º13? e 22º17? de latitude sul e 49º49? e 49º52? de longitude oeste. Está inserida no compartimento geomorfológico do Planalto Ocidental Paulista e, geologicamente, é caracterizada pelos arenitos cretácicos do Grupo Bauru, Formações Marília e Adamantina. O relevo varia de plano, nos topos e planícies aluviais, a montanhoso e escarpado, nas escarpas areníticas, predominando os relevos suave ondulado sob domínio dos solos latossolizados e ondulado nas áreas de ocorrência dos Podzólicos abruptos. O tipo climático predominante é Cwa, segundo a classificação de Köppen, com temperatura média anual de 21,4 ºC e pluviosidade média anual próxima a 1.500 mm. A cultura do café está entre as de maior importância nos relevos plano e suave ondulado sob domínio dos solos latossolizados, enquanto as pastagens estendem-se em grandes áreas dominadas com os Podzólicos abruptos eutróficos e álicos. Foram identificadas e cartografadas 9 unidades de solos na microbacia da Água Três Unidos, as quais apresentam uma estreita relação com o relevo. Assim, duas toposseqüências são predominantes na região. A primeira, caracteriza-se pela presença dos Latossolos Vermelho-Amarelos ou Vermelho-Escuros álicos ou distróficos nos topos aplainados, transicionando-se para os Podzólicos abruptos e Podzólicos latossólicos com o aumento da declividade, nas posições de ombro e terço superior das vertentes. Enquanto os abruptos podem ser álicos, distróficos e, predominantemente eutróficos, os Podzólicos latossólicos são essencialmente álicos ou distróficos, de textura binária arenosa/média, mais friáveis e de menor gradiente textural em relação aos Podzólicos abruptos. Sucedendo aos solos com B textural na toposseqüência, são encontrados solos poucos desenvolvidos (Solos Litólicos, Regossolos e Podzólicos abruptos rasos) nas proximidades das escarpas areníticas em relevo, predominantemente, ondulado e forte ondulado. Abaixo da escarpa, os Podzólicos abruptos são dominantes, predominantemente eutróficos, de textura binária arenosa/média e com características semelhantes àqueles localizados a montante da mesma, enquanto nas planícies aluviais predominam os solos hidromórficos (Gleissolos) e os aluviais em menores proporções. A segunda toposseqüência difere da anterior pela predominância dos Podzólicos Vermelho-Amarelos latossólicos nos topos, geralmente, mais estreitos e declivosos em relação aos locais de ocorrência de Latossolos.bitstream/CNPS/11839/1/bp12002lvtomicrobacia.pd

Phase equilibrium modelling of the amphibolite to granulite facies transition in metabasic rocks (Ivrea Zone, NW Italy)

The development of thermodynamic models for tonalitic melt and the updated clinopyroxene and amphibole models now allow the use of phase equilibrium modelling to estimate P–T conditions and melt production for anatectic mafic and intermediate rock types at high‐temperature conditions. The Permian mid‐lower crustal section of the Ivrea Zone preserves a metamorphic field gradient from mid amphibolite facies to granulite facies, and thus records the onset of partial melting in metabasic rocks. Interlayered metabasic and metapelitic rocks allows the direct comparison of P–T estimates and partial melting between both rock types with the same metamorphic evolution. Pseudosections for metabasic compositions calculated in the Na2O–CaO–K2O–FeO–MgO–Al2O3–SiO2–H2O–TiO2–O (NCKFMASHTO) system are presented and compared with those of metapelitic rocks calculated with consistent endmember data and a–x models. The results presented in this study show that P–T conditions obtained by phase equilibria modelling of both metabasic and metapelitic rocks give consistent results within uncertainties, allowing integration of results obtained for both rock types. In combination, the calculations for both metabasic and metapelitic rocks allows an updated and more precisely constrained metamorphic field gradient for Val Strona di Omegna to be defined. The new field gradient has a slightly lower dP/dT which is in better agreement with the onset of crustal thinning of the Adriatic margin during the Permian inferred in recent studies

Supramolecular amplification of amyloid self-assembly by iodination

Amyloid supramolecular assemblies have found widespread exploitation as ordered nanomaterials in a range of applications from materials science to biotechnology. New strategies are, however, required for understanding and promoting mature fibril formation from simple monomer motifs through easy and scalable processes. Noncovalent interactions are key to forming and holding the amyloid structure together. On the other hand, the halogen bond has never been used purposefully to achieve control over amyloid self-assembly. Here we show that single atom replacement of hydrogen with iodine, a halogen-bond donor, in the human calcitonin-derived amyloidogenic fragment DFNKF results in a super-gelator peptide, which forms a strong and shape-persistent hydrogel at 30-fold lower concentration than the wild-type pentapeptide. This is remarkable for such a modest perturbation in structure. Iodination of aromatic amino acids may thus develop as a general strategy for the design of new hydrogels from unprotected peptides and without using organic solvents

Systematic review of antiepileptic drugs’ safety and effectiveness in feline epilepsy

Understanding the efficacy and safety profile of antiepileptic drugs (AEDs) in feline epilepsy is a crucial consideration for managing this important brain disease. However, there is a lack of information about the treatment of feline epilepsy and therefore a systematic review was constructed to assess current evidence for the AEDs’ efficacy and tolerability in cats. The methods and materials of our former systematic reviews in canine epilepsy were mostly mirrored for the current systematic review in cats. Databases of PubMed, CAB Direct and Google scholar were searched to detect peer-reviewed studies reporting efficacy and/or adverse effects of AEDs in cats. The studies were assessed with regards to their quality of evidence, i.e. study design, study population, diagnostic criteria and overall risk of bias and the outcome measures reported, i.e. prevalence and 95% confidence interval of the successful and affected population in each study and in total

Zircon ages in granulite facies rocks: decoupling from geochemistry above 850 °C?

Granulite facies rocks frequently show a large spread in their zircon ages, the interpretation of which raises questions: Has the isotopic system been disturbed? By what process(es) and conditions did the alteration occur? Can the dates be regarded as real ages, reflecting several growth episodes? Furthermore, under some circumstances of (ultra-)high-temperature metamorphism, decoupling of zircon U–Pb dates from their trace element geochemistry has been reported. Understanding these processes is crucial to help interpret such dates in the context of the P–T history. Our study presents evidence for decoupling in zircon from the highest grade metapelites (> 850 °C) taken along a continuous high-temperature metamorphic field gradient in the Ivrea Zone (NW Italy). These rocks represent a well-characterised segment of Permian lower continental crust with a protracted high-temperature history. Cathodoluminescence images reveal that zircons in the mid-amphibolite facies preserve mainly detrital cores with narrow overgrowths. In the upper amphibolite and granulite facies, preserved detrital cores decrease and metamorphic zircon increases in quantity. Across all samples we document a sequence of four rim generations based on textures. U–Pb dates, Th/U ratios and Ti-in-zircon concentrations show an essentially continuous evolution with increasing metamorphic grade, except in the samples from the granulite facies, which display significant scatter in age and chemistry. We associate the observed decoupling of zircon systematics in high-grade non-metamict zircon with disturbance processes related to differences in behaviour of non-formula elements (i.e. Pb, Th, U, Ti) at high-temperature conditions, notably differences in compatibility within the crystal structure