pH-Impedance testing in gastro-oesophageal reflux

Gastro-Oesophageal Reflux Diseases (GORD) are one of the most common reasons for physician consultation. Out of 2,056 individuals randomly surveyed in the United States and Canada, up to 35% had more than one upper gastrointestinal symptom occurring at least once per week with at least moderate intensity. Investigation of GORD has evolved over the years.peer-reviewe

On computing fixpoints in well-structured regular model checking, with applications to lossy channel systems

We prove a general finite convergence theorem for "upward-guarded" fixpoint expressions over a well-quasi-ordered set. This has immediate applications in regular model checking of well-structured systems, where a main issue is the eventual convergence of fixpoint computations. In particular, we are able to directly obtain several new decidability results on lossy channel systems.Comment: 16 page

Reachability of Communicating Timed Processes

We study the reachability problem for communicating timed processes, both in discrete and dense time. Our model comprises automata with local timing constraints communicating over unbounded FIFO channels. Each automaton can only access its set of local clocks; all clocks evolve at the same rate. Our main contribution is a complete characterization of decidable and undecidable communication topologies, for both discrete and dense time. We also obtain complexity results, by showing that communicating timed processes are at least as hard as Petri nets; in the discrete time, we also show equivalence with Petri nets. Our results follow from mutual topology-preserving reductions between timed automata and (untimed) counter automata.Comment: Extended versio