3,448 research outputs found
Phase-averaged characterization of turbulent isothermal free swirling jet after vortex breakdown
This work mainly focused on the near-exit region of a round isothermal free swirling jet to characterize the effect of
swirl on the flow field and to identify large coherent structures. 3C-2D PIV was employed to capture the
instantaneous flow field close to the nozzle exit for non-swirling (S=0) and a high swirling jets (S=1.26) both with a
Reynolds number of 21800. At swirl level of 1.26 the pressure fluctuations measured by a capacitive microphone
indicate the existence of periodic instability, the so called precessing vortex core (PVC). A three-component proper
orthogonal decomposition (POD) applied to the instantaneous velocity fields allow to identify the dominant flow
structure associated to the PVC. The time coefficients of the two first most energetic POD modes were used to
reconstruct the phase of the oscillatory motion in the swirling flow. The phase information was then used to
conditionally average the instantaneous velocity field s, this allowed the 3D structure of the PVC to be reconstructed.
The instantaneous minima of negative swirling strength values calculated from the instantaneous velocity field
revealed the presence of two helical structures located in the inner and outer shear layers. By phase averaging the
instantaneous swirling strength maps, the 3D helical vortex structure was reconstructed . The two co-winding
counter-rotating helical structure fade out at an axial location of approximately z/ D = 1.5. The findings evidence
that the combined application of PIV, POD and frequency analysis using capacitive microphone can provide
detailed observations of coherent fluctuations ind uced by vortex precession
Posttransplant lymphoproliferative disorders in neuronal xenotransplanted macaques
Posttransplant lymphoproliferative disorders (PTLDs) are a heterogeneous group of lymphoid proliferations that occur in the setting of depressed T-cell function due to immunosuppressive therapy used following solid organ transplantation, hematopoietic stem cell transplantation, and also xenotransplantation. In the present study, 28 immunosuppressed parkinsonian Macaca fascicularis were intracerebrally injected with wild-type or CTLA4-Ig transgenic porcine xenografts to identify a suitable strategy to enable long-term cell survival, maturation, and differentiation. Nine of 28 (32%) immunosuppressed primates developed masses compatible with PTLD, located mainly in the gastrointestinal tract and/or nasal cavity. The masses were classified as monomorphic PTLD according to the World Health Organization classification. Immunohistochemistry and polymerase chain reaction (PCR) analyses revealed that the PTLDs were associated with macaca lymphocryptovirus as confirmed by double-labeling immunohistochemistry for CD20 and Epstein-Barr nuclear antigen 2 (EBNA-2), where the viral protein was located within the CD20+ neoplastic B cells. In sera from 3 distinct phases of the experimental life of the primates, testing by quantitative PCR revealed a progression of the viral load that paralleled the PTLD progression and no evidence of zoonotic transmission of porcine lymphotropic herpesvirus through xenoneuronal grafts. These data suggest that monitoring the variation of macaca lymphocryptovirus DNA in primates could be used as a possible early diagnostic tool for PTLD progression, allowing preemptive treatment such as immunosuppression therapy reduction
AN EXPERIMENTAL INVESTIGATION ON ISOTHERMAL FREE SWIRLING JET
This paper reports an experimental investigation on the dynamics of turbulent unconfined swirling flows. Isothermal free swirling jets with five different swirl
numbers (S) and fixed Reynolds number (Re = 21800) are investigated to analyze the effect of swirl intensity on the recirculation, vortex breakdown and the occurrence of the precession vortex core (PVC) by means of 3C-2D Stereoscopic Particle image velocimetry (PIV). The contours and radial profiles of mean axial velocity confirmed the central recirculation zone (CRZ) for high swirl number. The importance of central recirculation zone is to ensure a good mixing of air/ fuel and combustion products and to generate a low velocity region for flame stabilization. Results shows that swirl intensity increases the backflow rate in the recirculation zone and jet spreads almost linearly with a higher spread rate as compared to non swirling flow. The frequency characteristics have been measured with a capacitive microphone. The frequency spectrum indicates the presence of periodic oscillation related to the
existence of PVC. The Strouhal number associated with the frequency of the PVC vary almost linearly with swirl intensity
Nomenclature for the C60-Ih and C70-D5h(6) fullerenes (IUPAC Recommendations 2002)
Fullerenes are a new allotrope of carbon characterized by a closed-cage structure consisting of an even number of three-coordinate carbon atoms devoid of hydrogen atoms. This class was originally limited to closed-cage structures with 12 isolated five-membered rings, the rest being six-membered rings. Although it was recognized that existing organic ring nomenclature could be used for these structures, the resulting names would be extremely unwieldy and inconvenient for use. At the same time it was also recognized that established organic nomenclature principles could be used, or adapted, to provide a consistent nomenclature for this unique class of compounds based on the class name fullerene. However, it was necessary to develop an entirely new method for uniquely numbering closed-cage systems. This paper describes IUPAC recommendations for naming and uniquely numbering the two most common fullerenes with isolated pentagons, the icosahedral C60 fullerene and a D5h-C70 fullerene. It also describes recommendations for adapting organic nomenclature principles for naming fullerenes with nonclosed-cage structures, heterofullerenes, derivatives formed by substitution of hydrofullerenes, and the fusion of organic rings or ring systems to the fullerene cage. Finally, this paper suggests methods for describing structures consisting of two or more fullerene units and for denoting configurations of chiral fullerenes and their derivative
Experimental Observation of Non-Ideal Nozzle Flow of Siloxane Vapor MDM
The first experimental results from the Test-Rig for Organic Vapors (TROVA) at Politecnico di Milano are reported. The facility implements an Organic Rankine Cycle (ORC) where the expansion process takes place within a straight axis convergent-divergent nozzle, which is the simplest geometry representative of an ORC turbine blade passage. In order to reduce the required input thermal power, a batch operating mode was selected for the plant. Experimental runs with air allowed to verify the throttling valve operation and the measurement techniques, which include total pressure and temperature measurements in the settling chamber, static pressure measurements along the nozzle axis. A double-passage Schlieren technique is used to visualize the flow field in the nozzle throat and divergent section and to determine the position of shock waves within the flow field. The first experimental observation of non-ideal nozzle flows are presented for the expansion of siloxane fluid MDM (C8H24O2Si3, octamethyltrisiloxane) for vapor expansion in the close proximity of the liquid-vapor saturation curve, at relatively low pressure of operation. A supersonic flow is attained within the divergent section of the nozzle, as demonstrated by the observation of an oblique shock wave at the throat section, where a 0.1 mm recessed step is located. Schlieren visualizations are limited by the occurrence of condensation along the mirror side of the nozzle. Pressure measurements are compatible with the observed flow field
Experimental and numerical analysis of supersonic blade profiles developed for highly loaded impulse type steam turbine stages
The paper describes the results of a numerical and experimental research program addressing the aerodynamic investigation on the performance of blade profiles specifically developed for application in highly loaded impulse type turbine stages. The industrial requirements driving toward the adoption of highly loaded stage solutions are presented, along with an estimation of the profiles operating parameters. Two stator vanes and one rotor blade profile have been developed and extensively tested by means of flow field measurements and schlieren visualization in a transonic blow-down wind tunnel for linear cascades. Experimental results for the relevant operating conditions are presented, providing validation data for the CFD model used for blade design and evidencing that the main goals of the design optimization procedure have been achieved
Search for Intermediate Mass Magnetic Monopoles and Nuclearites with the SLIM experiment
SLIM is a large area experiment (440 m2) installed at the Chacaltaya cosmic
ray laboratory since 2001, and about 100 m2 at Koksil, Himalaya, since 2003. It
is devoted to the search for intermediate mass magnetic monopoles (107-1013
GeV/c2) and nuclearites in the cosmic radiation using stacks of CR39 and
Makrofol nuclear track detectors. In four years of operation it will reach a
sensitivity to a flux of about 10-15 cm-2 s-1 sr-1. We present the results of
the calibration of CR39 and Makrofol and the analysis of a first sample of the
exposed detector.Comment: Presented at the 22nd ICNTS, Barcelona 200
EXOSOMAL MICRORNA: POTENTIAL URINARY AND PLASMA BASED BIOMARKERS FOR THE DIAGNOSIS AND PROGNOSIS OF PROSTATE CANCER
Search for strange quark matter and Q-balls with the SLIM experiment
We report on the search for Strange Quark Matter (SQM) and charged Q-balls
with the SLIM experiment at the Chacaltaya High Altitude Laboratory (5230 m
a.s.l.) from 2001 to 2005. The SLIM experiment was a 427 m array of
Nuclear Track Detectors (NTDs) arranged in modules of cm
area. SLIM NTDs were exposed to the cosmic radiation for 4.22 years after which
they were brought back to the Bologna Laboratory where they were etched and
analyzed. We estimate the properties and energy losses in matter of nuclearites
(large SQM nuggets), strangelets (small charged SQM nuggets) and Q-balls; and
discuss their detection with the SLIM experiment. The flux upper limits in the
CR of such downgoing particles are at the level of /cm/s/sr
(90% CL).Comment: 4 pages, 7 eps figures. Talk given at the 24th International
Conference on Nuclear Tracks in Solids, Bologna, Italy, 1-5 September 200
Developing fencing policies in dryland ecosystems
The daily energy requirements of animals are determined by a combination of physical and physiological factors, but food availability may challenge the capacity to meet nutritional needs. Western gorillas (Gorilla gorilla) are an interesting model for investigating this topic because they are folivore-frugivores that adjust their diet and activities to seasonal variation in fruit availability. Observations of one habituated group of western gorillas in Bai-Hokou, Central African Republic (December 2004-December 2005) were used to examine seasonal variation in diet quality and nutritional intake. We tested if during the high fruit season the food consumed by western gorillas was higher in quality (higher in energy, sugar, fat but lower in fibre and antifeedants) than during the low fruit season. Food consumed during the high fruit season was higher in digestible energy, but not any other macronutrients. Second, we investigated whether the gorillas increased their daily intake of carbohydrates, metabolizable energy (KCal/g OM), or other nutrients during the high fruit season. Intake of dry matter, fibers, fat, protein and the majority of minerals and phenols decreased with increased frugivory and there was some indication of seasonal variation in intake of energy (KCal/g OM), tannins, protein/fiber ratio, and iron. Intake of non-structural carbohydrates and sugars was not influenced by fruit availability. Gorillas are probably able to extract large quantities of energy via fermentation since they rely on proteinaceous leaves during the low fruit season. Macronutrients and micronutrients, but not digestible energy, may be limited for them during times of low fruit availability because they are hind-gut fermenters. We discuss the advantages of seasonal frugivores having large dietary breath and flexibility, significant characteristics to consider in the conservation strategies of endangered species
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