DENTAL HEALTH EDUCATION FOR A COMMUNITY'S PARENTS *

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65215/1/j.1752-7325.1971.tb00592.x.pd

PREVENTION IN DENTISTRY AS VIEWED BY A DENTAL HEALTH EDUCATOR *

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65679/1/j.1752-7325.1973.tb00641.x.pd

Dynamic pathfinding for a swarm intelligence based UAV control model using particle swarm optimisation

In recent years unmanned aerial vehicles (UAVs) have become smaller, cheaper, and more efficient, enabling the use of multiple autonomous drones where previously a single, human-operated drone would have been used. This likely includes crisis response and search and rescue missions. These systems will need a method of navigating unknown and dynamic environments. Typically, this would require an incremental heuristic search algorithm, however, these algorithms become increasingly computationally and memory intensive as the environment size increases. This paper used two different Swarm Intelligence (SI) algorithms: Particle Swarm Optimisation and Reynolds flocking to propose an overall system for controlling and navigating groups of autonomous drones through unknown and dynamic environments. This paper proposes Particle Swarm Optimisation Pathfinding (PSOP): a dynamic, cooperative algorithm; and, Drone Flock Control (DFC): a modular model for controlling systems of agents, in 3D environments, such that collisions are minimised. Using the Unity game engine, a realtime application, simulation environment, and data collection apparatus were developed and the performances of DFC-controlled drones—navigating with either the PSOP algorithm or a D* Lite implementation—were compared. The simulations do not consider UAV dynamics. The drones were tasked with navigating to a given target position in environments of varying size and quantitative data on pathfinding performance, computational and memory performance, and usability were collected. Using this data, the advantages of PSO-based pathfinding were demonstrated. PSOP was shown to be more memory efficient, more successful in the creation of high quality, accurate paths, more usable and as computationally efficient as a typical incremental heuristic search algorithm when used as part of a SI-based drone control model. This study demonstrated the capabilities of SI approaches as a means of controlling multi-agent UAV systems in a simple simulation environment. Future research may look to apply the DFC model, with the PSOP algorithm, to more advanced simulations which considered environment factors like atmospheric pressure and turbulence, or to real-world UAVs in a controlled environment

Fundamental investigation of losses of skeletal mineral in young adult human males and collaterally in young adult male pigtail monkeys /macacus nemestrima/ through immobilization for varying periods of time, coupled with a study of methods of preven

Skeletal mineral losses in young adult humans and monkeys resulting from immobilizatio

Creating a STEM Identity: Investment with Return

Establishing a strong STEM (science, technology, engineering and mathematics) identity at Boise State University, a metropolitan campus with approximately 3,655 undergraduate STEM students and a total undergraduate enrollment of approximately 19,042 (16,136 FTE) has been an important step toward creating a climate conducive to facilitating fundamental change. Examples of such change include building collaborations among faculty within and across departments, establishing the identity of students as part of a community beyond their chosen major, improving the efficiency and effectiveness of university systems, and perhaps most importantly, developing a framework to think deliberately about ways to effect change. This paper is focused on describing and categorizing the development of a STEM “identity” over the past decade within a metropolitan campus that does not have an overall STEM central mission. The College of Engineering (CoE), established in 1997 as a result of a regional demand for engineering and computer science graduates, began focusing heavily on student success initiatives in 2004 with support from the Engineering Schools of the West Initiative, through the William and Flora Hewlett Foundation. This first wave of initiatives was critically assessed, and engineering student success became a focal point for the CoE. Internal research conducted under this grant exposed numerous roadblocks that impeded students\u27 academic success. In 2010, another large grant, funded through the National Science Foundation Science Talent Expansion Program (STEP), was awarded to increase the numbers of students graduating with STEM degrees. This grant engaged an interdisciplinary, cross-college team of STEM educators passionate about continuous improvement and pedagogical reform. Six months after the STEP grant launch, a second grant was awarded, a NSF Innovation through Institutional Integration (I^3) grant. All activities associated with these grants were deliberately categorized as “STEM” activities, in order to benefit all STEM students and faculty. This had the added benefit of unifying the STEM community and helping launch a sense of common purpose among STEM faculty and staff. We discuss a framework and present supporting cases to show how developing a STEM identity has been a critical step towards cross-curricular integration and improvements in pedagogical development, structures, policies and a sense of STEM community

Larvivorous fish for preventing malaria transmission.

Background Adult female Anopheles mosquitoes can transmit Plasmodium parasites that cause malaria. Some fish species eat mosquito larvae and pupae. In disease control policy documents, the World Health Organization (WHO) includes biological control of malaria vectors by stocking ponds, rivers, and water collections near where people live with larvivorous fish to reduce Plasmodium parasite transmission. In the past, the Global Fund has financed larvivorous fish programmes in some countries, and, with increasing efforts in eradication of malaria, policymakers may return to this option. Therefore, we assessed the evidence base for larvivorous fish programmes in malaria control. Objectives To evaluate whether introducing larvivorous fish to anopheline larval habitats impacts Plasmodium parasite transmission. We also sought to summarize studies that evaluated whether introducing larvivorous fish influences the density and presence of Anopheles larvae and pupae in water sources. Search methods We searched the Cochrane Infectious Diseases Group Specialized Register; the Cochrane Central Register of Controlled Trials (CENTRAL), published in the Cochrane Library; MEDLINE (PubMed); Embase (Ovid); CABS Abstracts; LILACS; and the metaRegister of Controlled Trials (mRCT) up to 6 July 2017. We checked the reference lists of all studies identified by the search. We examined references listed in review articles and previously compiled bibliographies to look for eligible studies. Also we contacted researchers in the field and the authors of studies that met the inclusion criteria for additional information regarding potential studies for inclusion and ongoing studies. This is an update of a Cochrane Review published in 2013. Selection criteria Randomized controlled trials (RCTs) and non-RCTs, including controlled before-and-after studies, controlled time series, and controlled interrupted time series studies from malaria-endemic regions that introduced fish as a larvicide and reported on malaria in the community or the density of the adult anopheline population. In the absence of direct evidence of an effect on transmission, we performed a secondary analysis on studies that evaluated the effect of introducing larvivorous fish on the density or presence of immature anopheline mosquitoes (larvae and pupae forms) in water sources to determine whether this intervention has any potential that may justify further research in the control of malaria vectors. Data collection and analysis Two review authors independently screened each article by title and abstract, and examined potentially relevant studies for inclusion using an eligibility form. At least two review authors independently extracted data and assessed risk of bias of included studies. If relevant data were unclear or were not reported, we contacted the study authors for clarification. We presented data in tables, and we summarized studies that evaluated the effects of introducing fish on anopheline immature density or presence, or both. We used the GRADE approach to summarize the certainty of the evidence. We also examined whether the included studies reported any possible adverse impact of introducing larvivorous fish on non-target native species. Main results We identified no studies that reported the effects of introducing larvivorous fish on the primary outcomes of this review: malaria infection in nearby communities, entomological inoculation rate, or on adult Anopheles density. For the secondary analysis, we examined the effects of introducing larvivorous fish on the density and presence of anopheline larvae and pupae in community water sources, and found 15 small studies with a follow-up period between 22 days and five years. These studies were undertaken in Sri Lanka (two studies), India (three studies), Ethiopia (one study), Kenya (two studies), Sudan (one study), Grande Comore Island (one study), Korea (two studies), Indonesia (one study), and Tajikistan (two studies). These studies were conducted in a variety of settings, including localized water bodies (such as wells, domestic water containers, fishponds, and pools (seven studies); riverbed pools below dams (two studies)); rice field plots (five studies); and water canals (two studies). All included studies were at high risk of bias. The research was insufficient to determine whether larvivorous fish reduce the density of Anopheles larvae and pupae (12 studies, unpooled data, very low certainty evidence). Some studies with high stocking levels of fish seemed to arrest the increase in immature anopheline populations, or to reduce the number of immature anopheline mosquitoes, compared with controls. However, this finding was not consistent, and in studies that showed a decrease in immature anopheline populations, the effect was not always consistently sustained. In contrast, some studies reported larvivorous fish reduced the number of water sources withAnopheles larvae and pupae (five studies, unpooled data, low certainty evidence). None of the included studies reported effects of larvivorous fish on local native fish populations or other species

Computational KIR copy number discovery reveals interaction between inhibitory receptor burden and survival.

Natural killer (NK) cells have increasingly become a target of interest for immunotherapies. NK cells express killer immunoglobulin-like receptors (KIRs), which play a vital role in immune response to tumors by detecting cellular abnormalities. The genomic region encoding the 16 KIR genes displays high polymorphic variability in human populations, making it difficult to resolve individual genotypes based on next generation sequencing data. As a result, the impact of polymorphic KIR variation on cancer phenotypes has been understudied. Currently, labor-intensive, experimental techniques are used to determine an individual's KIR gene copy number profile. Here, we develop an algorithm to determine the germline copy number of KIR genes from whole exome sequencing data and apply it to a cohort of nearly 5000 cancer patients. We use a k-mer based approach to capture sequences unique to specific genes, count their occurrences in the set of reads derived from an individual and compare the individual's k-mer distribution to that of the population. Copy number results demonstrate high concordance with population copy number expectations. Our method reveals that the burden of inhibitory KIR genes is associated with survival in two tumor types, highlighting the potential importance of KIR variation in understanding tumor development and response to immunotherapy