Ultrahigh-Energy Photons as a Probe of Nearby Transient Ultrahigh-Energy Cosmic-Ray Sources and Possible Lorentz-Invariance Violation

Detecting neutrinos and photons is crucial to identifying the sources of ultrahigh-energy cosmic rays (UHECRs), especially for transient sources. We focus on ultrahigh-energy gamma-ray emission from transient sources such as gamma-ray bursts, since >EeV gamma rays can be more direct evidence of UHECRs than PeV neutrinos and GeV-TeV gamma rays. We demonstrate that coincident detections of about 1-100 events can be expected by current and future UHECR detectors such as Auger and JEM-EUSO, and the detection probability can be higher than that of neutrinos for nearby transient sources at <50-100 Mpc. They may be useful for constraining the uncertain cosmic radio background as well as knowing the source properties and maximum energy of UHECRs. They can also give us more than 10^4 times stronger limits on the Lorentz-invariance violation than current constraints.Comment: 4 pages, 3 figures, replaced to match the published version (PRL, 103, 081102

Closure Relations for Electron-Positron Pair-Signatures in Gamma-Ray Bursts

We present recipes to diagnose the fireball of gamma-ray bursts (GRBs) by combining observations of electron-positron pair-signatures (the pair-annihilation line and the cutoff energy due to the pair-creation process). Our recipes are largely model-independent and extract information even from the non-detection of either pair-signature. We evaluate physical quantities such as the Lorentz factor, optical depth and pair-to-baryon ratio, only from the observable quantities. In particular, we can test whether the prompt emission of GRBs comes from the pair/baryonic photosphere or not. The future-coming Gamma-Ray Large Area Space Telescope (GLAST) satellite will provide us with good chances to use our recipes by detecting or non-detecting pair-signatures.Comment: 7 pages, 4 figures, accepted for publication in ApJ, with extended discussions. Conclusions unchange

Unstable GRB photospheres and electron-positron annihilation lines

We propose an emission mechanism of prompt gamma-ray bursts (GRBs) that can reproduce the observed non-thermal spectra with high radiative efficiencies, >50%. Internal dissipation below a photosphere can create a radiation-dominated thermal fireball. If electron-positron pairs outnumber protons, radiative acceleration of pairs drives the two-stream instabilities between pairs and protons, leading to the ``proton sedimentation'' in the accelerating pair frame. Pairs are continuously shock heated by proton clumps, scattering the thermal photons into the broken power-law shape, with the non-thermal energy that is comparable to the proton kinetic energy, consistent with observations. Pair photospheres become unstable around the radius of the progenitor star where strong thermalization occurs, if parameters satisfy the observed spectral (Yonetoku) relation. Pair annihilation lines are predicted above continua, which could be verified by GLAST.Comment: 4 pages, 2 figure

Genetic and Neural Modularity Underlie the Evolution of Schooling Behavior in Threespine Sticklebacks

SummaryAlthough descriptions of striking diversity in animal behavior are plentiful, little is known about the mechanisms by which behaviors change and evolve between groups. To fully understand behavioral evolution, it will be necessary to identify the genetic mechanisms that mediate behavioral change in a natural context [1–3]. Genetic analysis of behavior can also reveal associations between behavior and morphological or neural phenotypes, providing insight into the proximate mechanisms that control behavior. Relatively few studies to date have successfully identified genes or genomic regions that contribute to behavioral variation among natural populations or species [2], particularly in vertebrates [4–8]. Here, we apply genetic approaches to dissect a complex social behavior that has long fascinated biologists, schooling behavior [9–13]. We performed quantitative trait locus (QTL) analysis of schooling in an F2 intercross between strongly schooling marine and weakly schooling benthic sticklebacks (Gasterosteus aculeatus) and found that distinct genetic modules control different aspects of schooling behavior. Two key components of the behavior, tendency to school and body position when schooling, are uncorrelated in hybrids and map to different genomic regions. Our results further point to a genetic link between one behavioral component, schooling position, and variation in the neurosensory lateral line

High energy neutrino early afterglows from gamma-ray bursts revisited

The high energy neutrino emission from gamma-ray bursts (GRBs) has been expected in various scenarios. In this paper, we study the neutrino emission from early afterglows of GRBs, especially under the reverse-forward shock model and late prompt emission model. In the former model, the early afterglow emission occurs due to dissipation made by an external shock with the circumburst medium (CBM). In the latter model, internal dissipation such as internal shocks produces the shallow decay emission in early afterglows. We also discuss implications of recent Swift observations for neutrino signals in detail. Future neutrino detectors such as IceCube may detect neutrino signals from early afterglows, especially under the late prompt emission model, while the detection would be difficult under the reverse-forward shock model. Contribution to the neutrino background from the early afterglow emission may be at most comparable to that from the prompt emission unless the outflow making the early afterglow emission loads more nonthermal protons, and it may be important in the very high energies. Neutrino-detections are inviting because they could provide us with not only information on baryon acceleration but also one of the clues to the model of early afterglows. Finally, we compare various predictions for the neutrino background from GRBs, which are testable by future neutrino-observations.Comment: 18 pages, 12 figures, accepted for publication in PR

MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB

Autophagy is the major cellular pathway by which macromolecules are degraded, and amino acid depletion powerfully activates autophagy. MAP4K3, or germinal-center kinase-like kinase, is required for robust cell growth in response to amino acids, but the basis for MAP4K3 regulation of cellular metabolic disposition remains unknown. Here we identify MAP4K3 as an amino acid-dependent regulator of autophagy through its phosphorylation of transcription factor EB (TFEB), a transcriptional activator of autophagy, and through amino acid starvation-dependent lysosomal localization of MAP4K3. We document that MAP4K3 physically interacts with TFEB and MAP4K3 inhibition is sufficient for TFEB nuclear localization, target gene transactivation, and autophagy, even when mTORC1 is activated. Moreover, MAP4K3 serine 3 phosphorylation of TFEB is required for TFEB interaction with mTORC1-Rag GTPase-Ragulator complex and TFEB cytosolic sequestration. Our results uncover a role for MAP4K3 in the control of autophagy and reveal MAP4K3 as a central node in nutrient-sensing regulation

High Energy Neutrino Emission and Neutrino Background from Gamma-Ray Bursts in the Internal Shock Model

High energy neutrino emission from GRBs is discussed. In this paper, by using the simulation kit GEANT4, we calculate proton cooling efficiency including pion-multiplicity and proton-inelasticity in photomeson production. First, we estimate the maximum energy of accelerated protons in GRBs. Using the obtained results, neutrino flux from one burst and a diffuse neutrino background are evaluated quantitatively. We also take account of cooling processes of pion and muon, which are crucial for resulting neutrino spectra. We confirm the validity of analytic approximate treatments on GRB fiducial parameter sets, but also find that the effects of multiplicity and high-inelasticity can be important on both proton cooling and resulting spectra in some cases. Finally, assuming that the GRB rate traces the star formation rate, we obtain a diffuse neutrino background spectrum from GRBs for specific parameter sets. We introduce the nonthermal baryon-loading factor, rather than assume that GRBs are main sources of UHECRs. We find that the obtained neutrino background can be comparable with the prediction of Waxman & Bahcall, although our ground in estimation is different from theirs. In this paper, we study on various parameters since there are many parameters in the model. The detection of high energy neutrinos from GRBs will be one of the strong evidences that protons are accelerated to very high energy in GRBs. Furthermore, the observations of a neutrino background has a possibility not only to test the internal shock model of GRBs but also to give us information about parameters in the model and whether GRBs are sources of UHECRs or not.Comment: 14 pages, 17 figures, accepted for publication in PRD, with extended descriptions. Conclusions unchange

Chemical and Photometric Evolution of Extended Ultraviolet Disks: Optical Spectroscopy of M83 (NGC5236) and NGC4625

We present the results from the analysis of optical spectra of 31 Halpha-selected regions in the extended UV (XUV) disks of M83 (NGC5236) and NGC4625 recently discovered by GALEX. The spectra were obtained using IMACS at Las Campanas Observatory 6.5m Magellan I telescope and COSMIC at the Palomar 200-inch telescope, respectively for M83 and NGC4625. The line ratios measured indicate nebular oxygen abundances (derived from the R23 parameter) of the order of Zsun/5-Zsun/10. For most emission-line regions analyzed the line fluxes and ratios measured are best reproduced by models of photoionization by single stars with masses in the range 20-40 Msun and oxygen abundances comparable to those derived from the R23 parameter. We find indications for a relatively high N/O abundance ratio in the XUV disk of M83. Although the metallicities derived imply that these are not the first stars formed in the XUV disks, such a level of enrichment could be reached in young spiral disks only 1 Gyr after these first stars would have formed. The amount of gas in the XUV disks allow maintaining the current level of star formation for at least a few Gyr.Comment: 52 pages, 8 tables, 7 figures, accepted for publication in Ap

Dynamics of Scalar field in a Brane World

We study the dynamics of a scalar field in the brane cosmology. We assume that a scalar field is confined in our 4-dimensional world. As for the potential of the scalar field, we discuss three typical models: (1) a power-law potential, (2) an inverse-power-law potential, and (3) an exponential potential. We show that the behavior of the scalar field is very different from a conventional cosmology when the energy density square term is dominated.Comment: 15pages, 8figures, submitted to Physical Review

Galaxy Clusters as Reservoirs of Heavy Dark Matter and High-Energy Cosmic Rays: Constraints from Neutrino Observations

Galaxy Clusters (GCs) are the largest reservoirs of both dark matter and cosmic rays (CRs). Dark matter self-annihilation can lead to a high luminosity in gamma rays and neutrinos, enhanced by a strong degree of clustering in dark matter substructures. Hadronic CR interactions can also lead to a high luminosity in gamma rays and neutrinos, enhanced by the confinement of CRs from cluster accretion/merger shocks and active galactic nuclei. We show that IceCube/KM3Net observations of high-energy neutrinos can probe the nature of GCs and the separate dark matter and CR emission processes, taking into account how the results depend on the still-substantial uncertainties. Neutrino observations are relevant at high energies, especially at >10 TeV. Our results should be useful for improving experimental searches for high-energy neutrino emission. Neutrino telescopes are sensitive to extended sources formed by dark matter substructures and CRs distributed over large scales. Recent observations by Fermi and imaging atmospheric Cherenkov telescopes have placed interesting constraints on the gamma-ray emission from GCs. We also provide calculations of the gamma-ray fluxes, taking into account electromagnetic cascades inside GCs, which can be important for injections at sufficiently high energies. This also allows us to extend previous gamma-ray constraints to very high dark matter masses and significant CR injections at very high energies. Using both neutrinos and gamma rays, which can lead to comparable constraints, will allow more complete understandings of GCs. Neutrinos are essential for some dark matter annihilation channels, and for hadronic instead of electronic CRs. Our results suggest that the multi-messenger observations of GCs will be able to give useful constraints on specific models of dark matter and CRs. [Abstract abridged.]Comment: 31 pages, 20 figures, 1 table, accepted for publication in JCAP, references and discussions adde