Incidence of anthelmintic resistance in cattle farms in Northern Germany – first results

Anthelmintic resistance (AR) is an increasing problem worldwide especially for small ruminants and it is also rising in cattle. To maintain the efficacy of anthelmintics is an important objective. The current project aims at the investigation of the current efficacy of macrocyclic lactone anthelmintics for strongylid nematodes in first season grazing (FSG) calves in Northern Germany. On 8 participating farms in Northern Germany faecal egg count reduction tests (FECRT) with ivermectin (IVM) were performed. On 3 farms the efficacy of IVM was found to be ≤90% and on only 4 farms it was > 95% at 14 days post treatment (d.p.t.). Only 2 farms showed a reduction ≥ 95% at 21 d.p.t.. This survey reveals a rising problem of AR. The problem of drug resistance places the welfare of animals at risk. In organic farming, without a preventive treatment, livestock may harbour high worm counts. Therefore it is necessary to maintain powerful anthelmintic drugs to guarantee the welfare of animals that need salvage treatment. To investigate the AR problem in cattle more surveys with different anthelmintic drug classes are urgently needed

Remarks on E11 approach

We consider a few topics in $E_{11}$ approach to superstring/M-theory: even subgroups ($Z_2$ orbifolds) of $E_{n}$, n=11,10,9 and their connection to Kac-Moody algebras; $EE_{11}$ subgroup of $E_{11}$ and coincidence of one of its weights with the $l_1$ weight of $E_{11}$, known to contain brane charges; possible form of supersymmetry relation in $E_{11}$; decomposition of $l_1$ w.r.t. the $SO(10,10)$ and its square root at first few levels; particle orbit of $l_1 \ltimes E_{11}$. Possible relevance of coadjoint orbits method is noticed, based on a self-duality form of equations of motion in $E_{11}$.Comment: Two references adde

Dynamic Capabilities: Innovation Project Portfolio Management

Innovation Project Portfolio Management (IPPM) practices are a dynamic capability that provides competitive advantage by dynamically adjusting the organisation’s portfolio of projects and resource allocation profile for the best innovation outcomes. A relatively new body of empirical research into IPPM practices is starting to generate findings related to IPPM practices and innovation outcomes. However this research is fragmented and lacks a unifying theoretical base. The resource-based view of strategy, in particular the dynamic capabilities approach, provides a theoretical framework to unify IPPM research. A ‘processes, positions and paths’ perspective on IPPM practices helps to clarify the ways that IPPM practices contribute to competitive advantage. Existing empirical research into the processes used for IPPM reveals some links to innovation outcomes, but does not try to explain causality. Improved understanding of the mechanisms responsible for competitive advantage through IPPM practices is found in research on positions (how IPPM processes draw upon and contribute to the underlying resource position) and paths (the role of past decisions and organisational paths in shaping IPPM processes as well as future options and decisions).14 page(s

Project portfolio management for product innovation

The purpose of this paper is to create a benchmark and identify best practices for Project Portfolio Management (PPM) for both tangible product-based and service product-based development project portfolios. A questionnaire was developed to gather data to compare the PPM methods used, PPM performance, PPM challenges, and resulting new product success measures in 60 Australian organisations in a diverse range of service and manufacturing industries. The paper finds that PPM practices are shown to be very similar for service product development project portfolios and tangible product development project portfolios. New product success rates show strong correlation with measures of PPM performance and the use of some PPM methods is correlated with specific PPM performance outcomes. The findings in this paper are based on a survey of a diverse sample of 60 Australian organisations. The results are strengthened by comparisons with similar North American research; however, they may not be representative of all environments. Research in other regions would further qualify the findings. As each organisation's PPM process is unique, case study methods are recommended for future studies to capture more of the complexity in the environment. The paper shows that PPM practitioners and executives who make decisions about the development of tangible products and/or service products will benefit from the findings. This paper extends the existing understanding of PPM practices to include service development project portfolios as well as tangible product development project portfolios and strengthens the links between PPM practices and outcomes

Learning investments and organizational capabilities: case studies on the development of project portfolio management capabilities

Purpose The purpose of this paper is to improve understanding and provide guidance for investments in organizational learning mechanisms for the establishment and evolution of organizational capabilities such as project portfolio management (PPM) and project management capabilities. Design/methodology/approach A multiple-case study research project investigates the development of PPM capabilities in six successful organizations across diverse industries. Findings The research indicates that PPM and organizational learning are dynamic capabilities that enhance an organization's ability to achieve and maintain competitive advantage in dynamic environments. PPM capabilities are shown to co-evolve through a combination of tacit experience accumulation, explicit knowledge articulation and explicit knowledge codification learning mechanisms. Although all three learning mechanisms are important throughout the establishment and evolution of PPM capability development, the research indicates that the development of an effective PPM capability will require particularly strong investments in enhancing tacit experience accumulation mechanisms and explicit knowledge codification mechanisms during the initial establishment or during periods of radical change to the PPM process

Effects of nature of cooling surface on radiator performance

This report discusses the effects of roughness, smoothness, and cleanness of cooling surfaces on the performance of aeronautic radiators, as shown by experimental work, with different conditions of surface, on (1) heat transfer from a single brass tube and from a radiator; (2) pressure drop in an air stream in a single brass tube and in a radiator; (3) head resistance of a radiator; and (4) flow of air through a radiator. It is shown that while smooth surfaces are better than rough, the surfaces usually found in commercial radiators do not differ enough to show marked effect on performance, provided the surfaces are kept clean

Representations of involutory subalgebras of affine Kac-Moody algebras

We consider the subalgebras of split real, non-twisted affine Kac-Moody Lie algebras that are fixed by the Chevalley involution. These infinite-dimensional Lie algebras are not of Kac-Moody type and admit finite-dimensional unfaithful representations. We exhibit a formulation of these algebras in terms of $\mathbb{N}$-graded Lie algebras that allows the construction of a large class of representations using the techniques of induced representations. We study how these representations relate to previously established spinor representations as they arise in the theory of supergravity

Head Resistance Due to Radiators

Part 1 deals with the head resistance of a number of common types of radiator cores at different speeds in free air, as measured in the wind tunnel at the bureau of standards. This work was undertaken to determine the characteristics of various types of radiator cores, and in particular to develop the best type of radiator for airplanes. Some 25 specimens of core were tested, including practically all the general types now in use, except the flat plate type. Part 2 gives the results of wind tunnel tests of resistance on a model fuselage with a nose radiator. Part 3 presents the results of preliminary tests of head resistance of a radiator enclosed in a streamlined casing. Special attention is given to the value of wing radiator and of the radiator located in the open, especially when it is provided with a properly designed streamlined casing

Synopsis of aeronautic radiator investigations for years 1917 and 1918

Extensive series of experiments have been conducted at the Bureau of Standards to determine the properties of cooling radiator cores manufactured for airplanes and to develop improvements in design. The analysis of the problem on which this work was based, and consequently the experimental method employed, is different from that commonly used. Instead of attempting to test complete radiators, either full size or in model, uniform sections representing different types of core construction have been tested and an analysis of the results made with a view to determining independently the various factors which influence its performance. This report describes referenced method of analysis in predicting the performance of radiators designed for aeronautic use