101 research outputs found
Modeling Three and Four Coupled Phase Qubits
The Josephson junction phase qubit has been shown to be a viable candidate
for quantum computation. In recent years, the two coupled phase system has been
extensively studied theoretically and experimentally. We have analyzed the
quantum behavior of three and four capacitively-coupled phase qubits with
different possible configurations, using a two-level system model. Energy
levels and eigenstates have been calculated as a function of bias current and
detuning. The properties of these simple networks are discussed
Diffusing an Innovation: Clinician Perceptions of Continuous Predictive Analytics Monitoring in Intensive Care
Background The purpose of this article is to describe neonatal intensive care unit
clinician perceptions of a continuous predictive analytics technology and how those
perceptions influenced clinician adoption. Adopting and integrating new technology
into care is notoriously slow and difficult; realizing expected gains remain a challenge.
Methods Semistructured interviews from a cross-section of neonatal physicians
(n ¼ 14) and nurses (n ¼ 8) from a single U.S. medical center were collected 18 months
following the conclusion of the predictive monitoring technology randomized control
trial. Following qualitative descriptive analysis, innovation attributes from Diffusion of
Innovation Theory-guided thematic development.
Results Results suggest that the combination of physical location as well as lack of
integration into work flow or methods of using data in care decisionmaking may have
delayed clinicians from routinely paying attention to the data. Once data were routinely
collected, documented, and reported during patient rounds and patient handoffs,
clinicians came to view data as another vital sign. Through clinicians’ observation of
senior physicians and nurses, and ongoing dialogue about data trends and patient
status, clinicians learned how to integrate these data in care decision making (e.g.,
differential diagnosis) and came to value the technology as beneficial to care delivery.
Discussion The use of newly created predictive technologies that provide early warning of
illness may require implementation strategies that acknowledge the risk–benefit of
treatment cliniciansmust balance and take advantage of existing clinician trainingmethods
Comparison of diglyceride production from choline-containing phosphoglycerides in human neutrophils stimulated with N-formylmethionyl-leucylphenylalanine, ionophore A23187 or phorbol 12-myristate 13-acetate
WHS Guidelines for the Treatment of Pressure Ulcers: 2023 Update
The major populations at risk for developing pressure ulcers are older adults who have multiple risk factors that increase their vulnerability, people who are critically ill and those with spinal cord injury/disease. The reported prevalence of pressure ulcers in the United States is 2.5 million. However, this estimate is derived from acute care facilities and does not include people who are living at home or in nursing facilities. Despite the implementation of hospital and facility-based preventive measures, the incidence of pressure ulcers has not decreased in decades. In addition to the burden of pain, infection and death, it is estimated that hospital-acquired pressure ulcers cost the health system $26.8 billion annually with over 50% of the cost attributed to treating Stage 3 and 4 pressure injuries. Thus, it is critical to examine the literature and develop guidelines that will improve the outcomes of this complex and costly condition. This guideline update is a compendium of the best available evidence for the treatment of Pressure Ulcers published since the last update in 2015 and includes a new section based on changing demographics entitled ‘Palliative wound care for seriously ill patients with pressure ulcers’. The overall goal of the Wound Healing Society Guideline project is to present clear, concise and commercial free guidelines that clinicians can use to guide care, that researchers can use to develop studies that will improve treatment and that both clinicians and researchers can use to understand the gaps in our knowledge base
In situ protein Kinase C activity is increased in cultured fibroblasts from Type 1 diabetic patients with nephropathy
Efficient recovery of whole blood RNA - a comparison of commercial RNA extraction protocols for high-throughput applications in wildlife species
Models of classroom assessment for course-based research experiences
Course-based research pedagogy involves positioning students as contributors to authentic research projects as part of an engaging educational experience that promotes their learning and persistence in science. To develop a model for assessing and grading students engaged in this type of learning experience, the assessment aims and practices of a community of experienced course-based research instructors were collected and analyzed. This approach defines four aims of course-based research assessment—(1) Assessing Laboratory Work and Scientific Thinking; (2) Evaluating Mastery of Concepts, Quantitative Thinking and Skills; (3) Appraising Forms of Scientific Communication; and (4) Metacognition of Learning—along with a set of practices for each aim. These aims and practices of assessment were then integrated with previously developed models of course-based research instruction to reveal an assessment program in which instructors provide extensive feedback to support productive student engagement in research while grading those aspects of research that are necessary for the student to succeed. Assessment conducted in this way delicately balances the need to facilitate students’ ongoing research with the requirement of a final grade without undercutting the important aims of a CRE education
Stimulation of proximal convoluted tubule phosphate transport by epidermal growth factor: signal transduction
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