A city hall for Delhi and New Delhi (India)

Thesis (M.Arch)--Massachusetts Institute of Technology, Dept. of Architecture, 1960.Accompanying drawings held by MIT Museum.Includes bibliographical references (leaf 44).by R. N. Kacker.M.Arc

Late infantile epileptic encephalopathy: A distinct developmental and epileptic encephalopathy syndrome

Objective: Within the spectrum of developmental and epileptic encephalopathy (DEE), there are a group of infants with features that are distinct from the well-recognized syndromes of early infantile developmental and epileptic encephalopathy (EIDEE), infantile epileptic spasm syndrome (IESS), and Lennox-Gastaut syndrome (LGS). We refer to this condition as late infantile epileptic encephalopathy (LIEE). Our objective is to highlight the characteristics of this group by analyzing patients who exhibit prototypical features. Methods: From July 2022 to May 2023, we searched for LIEE features in pediatric patients who underwent epilepsy follow-up at the University of Chicago Comer Children's Hospital. Results: Out of 850 patients evaluated, thirty patients (3.5%) were identified with LIEE based on electroclinical characteristics. These patients had an average onset of epilepsy at 6.8 months and an average onset of LIEE features at 18.1 months. The epilepsy etiology was most commonly genetic and metabolic (50%), followed by congenital cortical malformations (23%), acquired structural abnormalities (20%), and unknown (7%). The predominant seizure types were myoclonic-tonic (70%), spasm-tonic (50%), epileptic spasms (47%), tonic (43%), and myoclonic (43%) seizures. All patients reported a history of either spasm-tonic or myoclonic-tonic seizures in addition to other types. All patients had EEGs showing discontinuity, electro-decrements, or both along with diffuse slowing, background voltages between 100-300 μV, and superimposed multifocal, diffuse epileptiform discharges. Every patient, except one, fulfilled the definition of drug-resistant epilepsy and all reported either moderate to severe developmental delay. Significance: Late infantile epileptic encephalopathy (LIEE) is characterized by several unique clinical and electrographic features. Typically, LIEE manifests in patients during the second year of life and occurs before two years of age, hence late-infantile onset. The condition is commonly observed in infants with symptomatic epilepsy. Myoclonic-tonic and spasm-tonic seizures are the quintessential seizure types. The inter-ictal EEG exhibits more organization and lower voltages than seen with hypsarhythmia and lacks the defining EEG characteristics of EIDEE, IESS, or LGS. We propose that LIEE is a distinct electroclinical syndrome within the spectrum of developmental and epileptic encephalopathies

Modeling Distillers Dried Grains with Solubles (DDGS) Mass Flow Rate as Affected by Drying and Storage Conditions

Ethanol production in 2015 was over 15 million gallons in the United States, and it is projected to increase in the next few years to meet market demands. With the continued growth in the ethanol industry, there has been enormous expansion in distillers grains production. Because the local market for distillers dried grains with solubles (DDGS) is often saturated, it is essential to transport DDGS long distances, across the United States and to international markets. Caking and agglomeration of DDGS particles in hoppers and other storage structures are typical during transportation. The current study deals with DDGS prepared by combining condensed distillers solubles (CDS) with distillers wet grains and then drying at varying temperatures. DDGS was stored in conical hoppers under varying ambient temperature, consolidation pressure, and time conditions. We investigated the effects of CDS (10, 15, and 20% wb), drying temperature (100, 200, and 300°C), drying time (20, 40, and 60 min), cooling temperature (0, 25, and 50°C), consolidation pressure (0, 1.72, and 3.43 kPa), and consolidation time (0, 3, and 6 days) levels on various flow parameters. To examine these factors, Taguchi’s experimental design with an L18 orthogonal array was implemented. Response surface modeling yielded mass flow rate = f(Hausner ratio, angle of repose) with R2 = 0.99, and it predicted moisture content for good, fair, and poor flow. Results showed that drying temperature, drying time, and cooling type were the main factors in predicting mass flow rate. The Johansson model for predicted mass flow rate was calibrated with experimental data, and a new parameter, compressibility factor, with a value of 0.96 g2/(min cm3), was determined to quantify the divergence of compressible and cohesive materials (such as DDGS) for free-flowing bulk solids. Thus, the predicted models may be beneficial for quantitative understanding of DDGS flow

Partial Cholecystectomy Safe and Effective

Patients undergoing surgical treatment for calculous disease were considered to have had a partial cholecystectomy performed when a part of the gall bladder wall was retained for technical reasons. Forty patients underwent partial cholecystectomy: for chronic cholecystitis (20), acute cholecystitis (4), Mirizzi's syndrome (14), portal hypertension or partially accesible gall bladder (one patient each). Four patients (10%) developed infective complications and two patients had retained common bile duct stones. In a mean follow up period of 13 months (range 1–36 mths), only 3 patients have ongoing mild dyspeptic symptoms while the rest have remained asymptomatic. Partial cholecystectomy has been found to be a safe and effective procedure in difficult cholecystectomy situations, since it combines the merits of cholecystectomy and cholecystostomy

Hepatoblastoma in an Adult with Biliary Obstruction and Associated Portal Venous Thrombosis

We present a case of adult hepatoblastoma. This young female presented with severe acute cholangitis. Preoperative diagnosis was common bile duct (CBD) obstruction with portal vein thrombosis. On exploration she had a tumor mass in the CBD. The unusual features of this case are discussed in this report

Correction due to finite speed of light in absolute gravimeters

Correction due to finite speed of light is among the most inconsistent ones in absolute gravimetry. Formulas reported by different authors yield corrections scattered up to 8 $\mu$Gal with no obvious reasons. The problem, though noted before, has never been studied, and nowadays the correction is rather postulated than rigorously proven. In this paper we make an attempt to revise the subject. Like other authors, we use physical models based on signal delays and the Doppler effect, however, in implementing the models we additionally introduce two scales of time associated with moving and resting reflectors, derive a set of rules to switch between the scales, and establish the equivalence of trajectory distortions as obtained from either time delay or distance progression. The obtained results enabled us to produce accurate correction formulas for different types of instruments, and to explain the differences in the results obtained by other authors. We found that the correction derived from the Doppler effect is accountable only for $\frac23$ of the total correction due to finite speed of light, if no signal delays are considered. Another major source of inconsistency was found in the tacit use of simplified trajectory models