Accessing emergency rest centres in the UK - lesson learnt

Emergency rest centres (ERC) are premises that are used for the temporary accommodation of evacuees during an emergency situation. They form an important part of emergency response, by providing a focal point for receiving people and providing food, shelter, information and support. The Disability Discrimination Act 2005 creates a legislative right for ‘reasonable’ access to goods and services for disabled people. This legislation does not differentiate between emergency and non emergency situations which means that those with a responsibility for emergency planning need to consider the accessibility of ERCs. This article examines ERC provision and reviews access for disabled people. It focuses on a study of three ERCs that were established in different local authority areas within the Yorkshire and Humber region in the UK during a flooding event on 25th June 2007. While uncovering many instances of good practise, the results from the research also identified a number of lessons to be learnt, in particular it was noted that the main barriers to access were encountered with: • Facilities and elements that did not comprise part of the buildings normal operation, such as the provision of bedding, medical assistance and effective communication; and • Facilities that would not normally be expected to be used to the extent, or duration, whilst the emergency rest centre was in operation, such as the provision of adequate welfare facilities. The research also noted that Civil Protection Legislation within the UK contains limited instruction or guidance to those with responsibility for Emergency Rest Centre provision. This provides little impetus for Emergency Planners to consider the needs of disabled people. This research has broad implications for local authorities and national government representatives. It identifies a need for those with responsibility for emergency planning and response to strengthen their knowledge of disabled people, and to adopt a more holistic approach to the provision of emergency planning and response

An observational prospective study of topical acidified nitrite for killing methicillin-resistant Staphylococcus aureus (MRSA) in contaminated wounds

Background Endogenous nitric oxide (NO) kills bacteria and other organisms as part of the innate immune response. When nitrite is exposed to low pH, NO is generated and has been used as an NO delivery system to treat skin infections. We demonstrated eradication of MRSA carriage from wounds using a topical formulation of citric acid (4.5%) and sodium nitrite (3%) creams co-applied for 5 days to 15 wounds in an observational prospective pilot study of 8 patients. Findings Following treatment with topical citric acid and sodium nitrite, 9 of 15 wounds (60%) and 3 of 8 patients (37%) were cleared of infection. MRSA isolates from these patients were all sensitive to acidified nitrite in vitro compared to methicillin-sensitive S. aureus and a reference strain of MRSA. Conclusions Nitric oxide and acidified nitrite offer a novel therapy for control of MRSA in wounds. Wounds that were not cleared of infection may have been re-contaminated or the bioavailability of acidified nitrite impaired by local factors in the tissue

The effects of riparian forestry on invertebrate drift and brown trout in upland streams of contrasting acidity

International audienceVariations in macroinvertebrate drift and benthic invertebrate abundance were assessed in 30 upland Welsh streams of varying acidity (pH 6.0) and riparian land-use (conifer, moorland or native broadleaf). The consequences for the diet and condition of wild brown trout Salmo trutta were also assessed. As expected from previous studies, there were significant reductions in benthic invertebrate abundance, aquatic drift density (by >60%), aquatic drift biomass (by >35%), total drift density (by >35%) and total drift biomass (by >20%) at acid sites by comparison with circumneutral sites due largely to the scarcity of mayflies. Absolute drift from terrestrial sources was unrelated to stream pH but formed a significantly greater proportion of total drift at acid sites (30-65% of density) than at circumneutral sites (20-40%) as aquatic contributions declined. Most of this apparent land use effect reflected significantly increased terrestrial drift under broadleaves. There was no significant reduction in terrestrial or aquatic drift at conifer forest sites per se after accounting for low pH. Trout diet varied substantially between locations partly reflecting variations in drift: significantly fewer mayflies and stoneflies were eaten at acid sites, and significantly more terrestrial prey were eaten under broadleaves. However, acidity did not reduce trout condition or gut-fullness. Unexpectedly, trout condition was significantly enhanced at conifer sites, irrespective of their pH. Hence, acidity has greater effects on the benthic abundance and drift density of invertebrates in upland streams than does riparian land use. However, trout forage flexibly enough to offset any possible food deficit, for example by switching to chironomids and terrestrial invertebrates. Enhanced terrestrial contributions to invertebrate drift from riparian broadleaf trees may be important in supplementing foraging opportunities for trout where aquatic prey are scarce. These data illustrate the value of native tree species in riparian locations in upland Britain and the energy subsidy they provide might well be disproportionately important for otherwise impoverished acid streams Keywords: brown trout, land-use, acidification, drift, forestry, stream

Microplastic ingestion by riverine macroinvertebrates

Although microplastics are a recognised pollutant in marine environments, less attention has been directed towards freshwater ecosystems despite their greater proximity to possible plastic sources. Here, we quantify the presence of microplastic particles (MPs) in river organisms upstream and downstream of five UK Wastewater Treatment Works (WwTWs). MPs were identified in approximately 50% of macroinvertebrate samples collected (Baetidae, Heptageniidae and Hydropsychidae) at concentrations up to 0.14 MP mg tissue−1 and they occurred at all sites. MP abundance was associated with macroinvertebrate biomass and taxonomic family, but MPs occurred independently of feeding guild and biological traits such as habitat affinity and ecological niche. There was no increase in plastic ingestion downstream of WwTW discharges averaged across sites, but MP abundance in macroinvertebrates marginally increased where effluent discharges contributed more to total runoff and declined with increasing river discharge. The ubiquity of microplastics within macroinvertebrates in this case study reveals a potential risk from MPs entering riverine food webs through at least two pathways, involving detritivory and filter-feeding, and we recommend closer attention to freshwater ecosystems in future research

Differential effects of phototherapy, adalimumab and betamethasone/calcipotriol on effector and regulatory T cells in psoriasis

I.S.K. thanks the Egyptian Government for financial support through the Egyptian Cultural Bureau Office. This work was partially supported by a National Health Service endowment grant RG12745 to A.D.O. and I.S.K. We thank Linda Lawson,the biologics nurse, all the staff members at the dermatology department and the participants.Peer reviewedPostprin

Biological traits and the transfer of persistent organic pollutants through river food webs

Freshwater organisms remain at risk from bioaccumulation and biomagnification of persistent organic pollutants (POPs), but factors affecting their transfer through food webs are poorly understood. Here, we investigate transfer pathways of polychlorinated biphenyls, polybrominated diphenyl ethers, and organochlorine through a river food web, assessing the distribution and flux between basal resources (n = 3), macroinvertebrates (n = 22), and fish (n = 1). We investigate the effects of biological traits on the observed patterns and use trait-based models to predict POP bioaccumulation. Transfer pathways differed among POPs and traits such as habitat affinity, feeding behavior, and body size explained some variation in POP burdens between organisms. Trait-based models indicated that relationships between POPs, trophic transfers, and traits were relatively well conserved across a wider array of river food webs. Although providing more consistent predictions of POP bioaccumulation than steady-state models, variability in bioaccumulation across food webs limited the accuracy of trait-model predictions. As some of the first data to illustrate how ecological processes alter the flux of pollutants through river food webs, these results reveal important links between POPs and contrasting energetic pathways. These data also show the utility of trait-based methods in the assessment of persistent contaminants, but further field validations are required

Evolution: Complexity, uncertainty and innovation

Complexity science provides a general mathematical basis for evolutionary thinking. It makes us face the inherent, irreducible nature of uncertainty and the limits to knowledge and prediction. Complex, evolutionary systems work on the basis of on-going, continuous internal processes of exploration, experimentation and innovation at their underlying levels. This is acted upon by the level above, leading to a selection process on the lower levels and a probing of the stability of the level above. This could either be an organizational level above, or the potential market place. Models aimed at predicting system behaviour therefore consist of assumptions of constraints on the micro-level – and because of inertia or conformity may be approximately true for some unspecified time. However, systems without strong mechanisms of repression and conformity will evolve, innovate and change, creating new emergent structures, capabilities and characteristics. Systems with no individual freedom at their lower levels will have predictable behaviour in the short term – but will not survive in the long term. Creative, innovative, evolving systems, on the other hand, will more probably survive over longer times, but will not have predictable characteristics or behaviour. These minimal mechanisms are all that are required to explain (though not predict) the co-evolutionary processes occurring in markets, organizations, and indeed in emergent, evolutionary communities of practice. Some examples will be presented briefly

The statistical laws of popularity: Universal properties of the box office dynamics of motion pictures

Are there general principles governing the process by which certain products or ideas become popular relative to other (often qualitatively similar) competitors? To investigate this question in detail, we have focused on the popularity of movies as measured by their box-office income. We observe that the log-normal distribution describes well the tail (corresponding to the most successful movies) of the empirical distributions for the total income, the income on the opening week, as well as, the weekly income per theater. This observation suggests that popularity may be the outcome of a linear multiplicative stochastic process. In addition, the distributions of the total income and the opening income show a bimodal form, with the majority of movies either performing very well or very poorly in theaters. We also observe that the gross income per theater for a movie at any point during its lifetime is, on average, inversely proportional to the period that has elapsed after its release. We argue that (i) the log-normal nature of the tail, (ii) the bimodal form of the overall gross income distribution, and (iii) the decay of gross income per theater with time as a power law, constitute the fundamental set of {\em stylized facts} (i.e., empirical "laws") that can be used to explain other observations about movie popularity. We show that, in conjunction with an assumption of a fixed lower cut-off for income per theater below which a movie is withdrawn from a cinema, these laws can be used to derive a Weibull distribution for the survival probability of movies which agrees with empirical data. The connection to extreme-value distributions suggests that popularity can be viewed as a process where a product becomes popular by avoiding failure (i.e., being pulled out from circulation) for many successive time periods. We suggest that these results may apply to popularity in general.Comment: 14 pages, 11 figure