18 research outputs found
Value of Color-Doppler Imaging in Diagnosis of Intrabulbar and Intraorbital Tumors
Patients with intrabulbar and intraorbital tumours have been investigated by colour Doppler imaging. In the first group there were 20 patients with malignant melanoma of the uvea and in the second group there were 19 patients with cavernous hemangioma. The third group was a control group represented by 20 healthy individuals. In the group of patients with uveal melanoma it has been established that every patient, except one, has a blood flow inside of tumour tissue. Internal blood flow of intraorbital hemangioma was slower than inside the melanoma and the resistance index was lower. Comparison of blood flow in all patients has shown that there is no statistically significant difference between ophthalmic artery, central retinal artery and posterior ciliary arteries except in maximal blood flow in central retinal artery and posterior ciliary arteries
SiPP (Stroke in Pregnancy and Postpartum): A prospective,observational, international, multicentre study on pathophysiological mechanisms, clinical profile, management and outcome of cerebrovascular diseases in pregnant and postpartum women
Abstract
Rationale: Cerebrovascular diseases associated with pregnancy and postpartum period are uncommon; however, they can have an important impact on health of both women and foetus or newborn. Aims: To evaluate the frequency, characteristics and management of cerebrovascular events in pregnant/postpartum women, to clarify pathophysiological mechanisms underlying the occurrence of these events including biomolecular
aspects, and to assess the short- and long-term cerebrovascular and global cardiovascular outcome of these patients,their predictors and infant outcome.
Methods and design: This is an observational, prospective, multicentre, international case–control study. The study will include patients with cerebrovascular events during pregnancy and/or within six months after delivery. For each included case, two controls will be prospectively recruited: one pregnant or puerperal subject without any history of cerebrovascular event and one non-pregnant or non-puerperal subject with a recent cerebrovascular event. All controls
will be matched by age, ethnicity and type of cerebrovascular event with their assigned cases. The pregnant controls
will be matched also by pregnancy weeks/trimester. Follow-up will last 24 months for the mother and 12 months for the infant.
Summary: To better understand causes and outcomes of uncommon conditions like pregnancy/postpartum-related
cerebrovascular events, the development of multisite, multidisciplinary registry-based studies, such as the Stroke in Pregnancy and Postpartum study, is needed in order to collect an adequate number of patients, draw reliable conclusions
and give definite recommendations on their management.
© European Stroke Organisation 2019
SiPP (Stroke in Pregnancy and Postpartum): A prospective, observational, international, multicentre study on pathophysiological mechanisms, clinical profile, management and outcome of cerebrovascular diseases in pregnant and postpartum women
Rationale: Cerebrovascular diseases associated with pregnancy and postpartum period are uncommon; however, they can have an important impact on health of both women and foetus or newborn. Aims: To evaluate the frequency, characteristics and management of cerebrovascular events in pregnant/postpartum women, to clarify pathophysiological mechanisms underlying the occurrence of these events including biomolecular aspects, and to assess the short- and long-term cerebrovascular and global cardiovascular outcome of these patients, their predictors and infant outcome. Methods and design: This is an observational, prospective, multicentre, international case–control study. The study will include patients with cerebrovascular events during pregnancy and/or within six months after delivery. For each included case, two controls will be prospectively recruited: one pregnant or puerperal subject without any history of cerebrovascular event and one non-pregnant or non-puerperal subject with a recent cerebrovascular event. All controls will be matched by age, ethnicity and type of cerebrovascular event with their assigned cases. The pregnant controls will be matched also by pregnancy weeks/trimester. Follow-up will last 24 months for the mother and 12 months for the infant. Summary: To better understand causes and outcomes of uncommon conditions like pregnancy/postpartum-related cerebrovascular events, the development of multisite, multidisciplinary registry-based studies, such as the Stroke in Pregnancy and Postpartum study, is needed in order to collect an adequate number of patients, draw reliable conclusions and give definite recommendations on their management. © European Stroke Organisation 2019
SiPP (Stroke in Pregnancy and Postpartum): A prospective, observational, international, multicentre study on pathophysiological mechanisms, clinical profile, management and outcome of cerebrovascular diseases in pregnant and postpartum women
Rationale: Cerebrovascular diseases associated with pregnancy and postpartum period are uncommon; however, they
can have an important impact on health of both women and foetus or newborn.
Aims: To evaluate the frequency, characteristics and management of cerebrovascular events in pregnant/postpartum
women, to clarify pathophysiological mechanisms underlying the occurrence of these events including biomolecular
aspects, and to assess the short- and long-term cerebrovascular and global cardiovascular outcome of these patients,
their predictors and infant outcome.
Methods and design: This is an observational, prospective, multicentre, international case–control study. The study
will include patients with cerebrovascular events during pregnancy and/or within six months after delivery. For each
included case, two controls will be prospectively recruited: one pregnant or puerperal subject without any history of
cerebrovascular event and one non-pregnant or non-puerperal subject with a recent cerebrovascular event. All controls
will be matched by age, ethnicity and type of cerebrovascular event with their assigned cases. The pregnant controls
will be matched also by pregnancy weeks/trimester. Follow-up will last 24 months for the mother and 12 months for
the infant.
Summary: To better understand causes and outcomes of uncommon conditions like pregnancy/postpartum-related
cerebrovascular events, the development of multisite, multidisciplinary registry-based studies, such as the Stroke in
Pregnancy and Postpartum study, is needed in order to collect an adequate number of patients, draw reliable conclusions
and give definite recommendations on their manageme