798 research outputs found
âsome kind of thing it aint us but yet its in usâ: David Mitchell, Russell Hoban, and metafiction after the millennium
This article appraises the debt that David Mitchellâs Cloud Atlas owes to the novels of Russell Hoban, including, but not limited to, Riddley Walker. After clearly mapping a history of Hobanâs philosophical perspectives and Mitchellâs inter-textual genre-impersonation practice, the article assesses the degree to which Mitchellâs metatextual methods indicate a nostalgia for by-gone radical aesthetics rather than reaching for new modes of its own. The article not only proposes several new backdrops against which Mitchellâs novel can be read but also conducts the first in-depth appraisal of Mitchellâs formal linguistic replication of Riddley Walker
Results of the 1977 southern California pismo clam survey
A Pismo clam, Tivela stultorum, survey was conducted
in January 1977 on selected southern California beaches.
Effort and catch information was collected through clammer interviews. Estimates for the two day survey were 1,596
clammers spending 2,506 hours to take 6,139 clams. Comparisons were made between the 1977 survey results and
previous surveys.
Clams were collected for length and age studies. Compliance
to the 4.5-inch (114.3 mm) minimum size limit appeared to be good. (15pp.
Unbounded randomness certification using sequences of measurements
Unpredictability, or randomness, of the outcomes of measurements made on an
entangled state can be certified provided that the statistics violate a Bell
inequality. In the standard Bell scenario where each party performs a single
measurement on its share of the system, only a finite amount of randomness, of
at most bits, can be certified from a pair of entangled particles
of dimension . Our work shows that this fundamental limitation can be
overcome using sequences of (nonprojective) measurements on the same system.
More precisely, we prove that one can certify any amount of random bits from a
pair of qubits in a pure state as the resource, even if it is arbitrarily
weakly entangled. In addition, this certification is achieved by near-maximal
violation of a particular Bell inequality for each measurement in the sequence.Comment: 4 + 5 pages (1 + 3 images), published versio
Social and Demographic Influences on Environmental Attitudes
Sociologists have studied environmental attitudes for over two decades. Much of this research has sought to determine what factors are related to these attitudes. Past research has shown that certain social and demographic variables tend to have a positive influence on environmentalism. One of the more valid and reliable indicators of environmentalism is the 12-item attitude scale known as the New Environmental Paradigm (NEP). That scale has been shown to consist of three sub-scales. This paper extends previous research by examining the relative influence of six independent variables (age, gender, race, education, income, and residence) on each of the sub-scales and the overall NEP scale. The analysis generally supports the hypotheses that younger people, women, whites, and people of higher education levels hold more environmental attitudes as measured by the NEP index. Income has a significant nonlinear effect
In-vitro activity of OPC-17116 against more than 6000 consecutive clinical isolates: a multicentre international study
Generalized Bell Inequality Experiments and Computation
We consider general settings of Bell inequality experiments with many
parties, where each party chooses from a finite number of measurement settings
each with a finite number of outcomes. We investigate the constraints that Bell
inequalities place upon the correlations possible in a local hidden variable
theories using a geometrical picture of correlations. We show that local hidden
variable theories can be characterized in terms of limited computational
expressiveness, which allows us to characterize families of Bell inequalities.
The limited computational expressiveness for many settings (each with many
outcomes) generalizes previous results about the many-party situation each with
a choice of two possible measurements (each with two outcomes). Using this
computational picture we present generalizations of the Popescu-Rohrlich
non-local box for many parties and non-binary inputs and outputs at each site.
Finally, we comment on the effect of pre-processing on measurement data in our
generalized setting and show that it becomes problematic outside of the binary
setting, in that it allows local hidden variable theories to simulate maximally
non-local correlations such as those of these generalised Popescu-Rohrlich
non-local boxes.Comment: 16 pages, 2 figures, supplemental material available upon request.
Typos corrected and references adde
The effect of lamb carcase weight and GR depth on the production of value-added cuts â A short communication
Times for the progressive breakdown of 95 lamb carcases were recorded to determine the impact of carcase weight and GR tissue depth on the time and therefore cost to produce value added retail cuts. Further analysis also assessed the potential to use these carcase traits as predictors of fabrication times. Regression modeling demonstrated there was a limited ability to predict the difference in time to fabricate mid value-added (R2 = 0.18) and extreme value-added (R2 = 0.12) cuts compared to traditional cuts, suggesting that other factors need to be considered. However, this study highlighted the significant increases in time required to fabricate more value-added cuts and to breakdown heavier carcases. Furthermore, this study demonstrated the changes to the saleable meat yield as the degree of fabrication increased, such that the average product prices increased (28.72/kg for extreme value added) compared to traditional retail cuts ($15/kg) to offset the increased labour of fabricating value-added cuts
The human ankyrin 1 promoter insulator sustains gene expression in a ÎČ-globin lentiviral vector in hematopoietic stem cells.
Lentiviral vectors designed for the treatment of the hemoglobinopathies require the inclusion of regulatory and strong enhancer elements to achieve sufficient expression of the ÎČ-globin transgene. Despite the inclusion of these elements, the efficacy of these vectors may be limited by transgene silencing due to the genomic environment surrounding the integration site. Barrier insulators can be used to give more consistent expression and resist silencing even with lower vector copies. Here, the barrier activity of an insulator element from the human ankyrin-1 gene was analyzed in a lentiviral vector carrying an antisickling human ÎČ-globin gene. Inclusion of a single copy of the Ankyrin insulator did not affect viral titer, and improved the consistency of expression from the vector in murine erythroleukemia cells. The presence of the Ankyrin insulator element did not change transgene expression in human hematopoietic cells in short-term erythroid culture or in vivo in primary murine transplants. However, analysis in secondary recipients showed that the lentiviral vector with the Ankyrin element preserved transgene expression, whereas expression from the vector lacking the Ankyrin insulator decreased in secondary recipients. These studies demonstrate that the Ankyrin insulator may improve long-term ÎČ-globin expression in hematopoietic stem cells for gene therapy of hemoglobinopathies
Multi-Drug Resistant (MDR) S. aureus Against Tigecycline and Comparators: A Global Evaluation
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