Extracting B→K∗B \to K^* Form Factors from Data

We extract ratios of $B \to K^*$ form factors at low hadronic recoil from recent data on $B \to K^* \mu^+ \mu^-$ decays in a model-independent way. The presented method will improve in the future with further (angular) studies in semileptonic rare B-decays and advance our understanding of form factors, which are important inputs in precision tests of the Standard Model

Katalogisierungskulturen in den USA und Deutschland – ein Vergleich / Comparing cataloging cultures in the US and Germany

Wie wird man Formal- bzw. Sacherschließer? Was macht ein Formal- bzw. Sacherschließer? Unterschiedliche Traditionen. Ausblick in die Zukunft Unterschiede in der derzeitigen Erschließungspraxis Kooperative Erschließungsprogramme Herkunft bibliografischer Datensätze: Wo kommen sie her? Herausforderungen der Zukunf

До проблеми міжетнічних контактів сарматських племен Північного Причорномор’я перших століть нашої ери (за матеріалами ліпної кераміки)

(uk) Стаття присвячена дослідженню проблем трансформації сарматського ліпного керамічного комплексу як вияву міжетнічної взаємодії племен Північного Причорномор’я І – ІV ст. н.е.(en) The article investigates the problems of transformation of Sarmatian ceramic plastic complex as a manifestation of interethnic interaction of the tribes of Northern Prychornomorya in the I – IV centuries A.D

Risk factors for severe postoperative complications in dogs with cranial cruciate ligament disease-A survival analysis

Objective: To analyze the effect of surgical technique and other risk factors on severe postoperative complications in dogs with cranial cruciate ligament disease (CCLD). Materials and Methods: A cohort study of 255 dogs (287 stifles) surgically treated for CCLD at two veterinary university hospitals (2011 & ndash;2016) was performed. The electronic medical records were reviewed and dog owners and referring veterinarians contacted for additional information. The complications were classified as minor, major and catastrophic, where major and catastrophic were considered severe. A multivariable Cox proportional hazards model was applied to assess risk factors for severe postoperative complications.Results: Three surgical techniques were used; lateral fabellotibial suture (LFS, 141 stifles), tibial plateau leveling osteotomy (TPLO, 77 stifles) and tibial tuberosity advancement (TTA, 69 stifles). The most common severe postoperative complications were surgical site infections or complications related to the surgical implant. Severe postoperative complications occurred in 31 % of the stifles treated with TPLO, 22 % of the stifles treated with LFS and 25 % of the stifles treated with TTA. The multivariable Cox proportional hazards model identified surgical technique (p = 0.0258) as a risk factor for severe postoperative complications; TPLO had a significantly lower hazard than LFS (hazard ratio (HR) = 0.37, p = 0.007) when controlling for body weight and age, which also were identified as risk factors (HR = 1.05, p < 0.001 and HR = 0.91, p = 0.047, respectively).Conclusion and Clinical relevance: Although TPLO procedures had the highest occurrence of severe postoperative complications, the hazard was lower than for LFS after adjusting for body weight and age. This implies that it is important to consider potential effect-modifiers when comparing postoperative complications after CCLD surgery

Further Characterization of Dopamine Release by Permeabilized PC 12 Cells

Rat pheochromocytoma cells (PC 12) permeabilized with staphylococcal α-toxin release [3H]dopamine after addition of micromolar Ca2+. This does not require additional Mg2+-ATP (in contrast to bovine adrenal medullary chromaffin cells). We also observed Ca2+-dependent [3H]-dopamine release from digitonin-permeabilized PC 12 cells. Permeabilization with α-toxin or digitonin and stimulation of the cells were done consecutively to wash out endogenous Mg2+-ATP. During permeabilization, ATP was removed effectively from the cytoplasm by both agents but the cells released [3H]dopamine in response to micromolar Ca2+ alone. Replacement by chloride of glutamate, which could sustain mitochondrial ATP production in permeabilized cells, does not significantly alter catecholamine release induced by Ca2+. However, Mg2+ without ATP augments the Ca2+-induced release. The release was unaltered by thiol-, hydroxyl-, or calmodulin-interfering substances. Thus Mg2+-ATP, calmodulin, or proteins containing -SH or -OH groups are not necessary for exocytosis in permeabilized PC 12 cells

Розвиток творчої активності студентів-гітаристів через імпровізацію під час роботи над музичним твором

(uk) У статті розглядається питання розвитку творчої активності студентів-гітарістів. Надається обґрунтування того, що одним з ефективних засобів розвитку творчої активності студентів-гітарістів є високий рівень засвоєння прийомів імпровізації на заняттях з основного музичного інструменту. Наголошується, що розвиток творчого потенціалу в процесі музично-творчої діяльності студентів буде ефективним за умов здійснення педагогічного керівництва.(ru) В статье рассматривается вопрос развития творческой активности студентов-гитаристов. Предоставляется обоснование того, что одним из эффективных средств развития творческой активности студентов-гитаристов является высокий уровень усвоения приемов импровизации на занятиях основного музыкального инструмента. Отмечается, что развитие творческого потенциала в процессе музыкально-творческой деятельности студентов будет эффективным в условиях осуществления педагогического руководства.(en) This article deals with the development of the creative activity of students guitarists. The ground of being one of the most effective means of creative activity of students guitarists is a high level of mastering techniques of improvisation in the classroom with the main musical instrument. It is noted that the development of creativity in the process of musical and creative activities students will be effective on condition that educational leadership. ndependent work on a musical composition is a productive form of developing students creative musical thinking. In the work plan of the students must be enabled as works of high complexity and fragments or themes from the works that are very difficult to implement fully. The basic weight school repertoire is designed for self-study students

Resolvins: A Family of Bioactive Products of Omega-3 Fatty Acid Transformation Circuits Initiated by Aspirin Treatment that Counter Proinflammation Signals

Aspirin (ASA) is unique among current therapies because it acetylates cyclooxygenase (COX)-2 enabling the biosynthesis of R-containing precursors of endogenous antiinflammatory mediators. Here, we report that lipidomic analysis of exudates obtained in the resolution phase from mice treated with ASA and docosahexaenoic acid (DHA) (C22:6) produce a novel family of bioactive 17R-hydroxy-containing di- and tri-hydroxy-docosanoids termed resolvins. Murine brain treated with aspirin produced endogenous 17R-hydroxydocosahexaenoic acid as did human microglial cells. Human COX-2 converted DHA to 13-hydroxy-DHA that switched with ASA to 17R-HDHA that also proved a major route in hypoxic endothelial cells. Human neutrophils transformed COX-2-ASA–derived 17R-hydroxy-DHA into two sets of novel di- and trihydroxy products; one initiated via oxygenation at carbon 7 and the other at carbon 4. These compounds inhibited (IC50 ∼50 pM) microglial cell cytokine expression and in vivo dermal inflammation and peritonitis at ng doses, reducing 40–80% leukocytic exudates. These results indicate that exudates, vascular, leukocytes and neural cells treated with aspirin convert DHA to novel 17R-hydroxy series of docosanoids that are potent regulators. These biosynthetic pathways utilize omega-3 DHA and EPA during multicellular events in resolution to produce a family of protective compounds, i.e., resolvins, that enhance proresolution status