Spin thermoelectrics in a disordered Fermi gas

We study the connection between the spin-heat and spin-charge response in a disordered Fermi gas with spin-orbit coupling. It is shown that the ratio between the above responses can be expressed as the thermopower $S=-(\pi k_B)^2T\sigma'/3e\sigma$ times a number $R_s$ which depends on the strength and type of the spin-orbit couplings considered. The general results are illustrated by examining different two-dimensional electron or hole systems with different and competing spin-orbit mechanisms, and we conclude that a metallic system could prove much more efficient as a heat-to-spin than as a heat-to-charge converter.Comment: 6 pages, 1 figur

Onsager relations in a two-dimensional electron gas with spin-orbit coupling

Theory predicts for the two-dimensional electrons gas with only Rashba spin-orbit interaction a vanishing spin Hall conductivity and at the same time a finite inverse spin Hall effect. We show how these seemingly contradictory results are compatible with the Onsager relations: the latter do hold for spin and particle (charge) currents in the two-dimensional electron gas, although (i) their form depends on the experimental setup and (ii) a vanishing bulk spin Hall conductivity does not necessarily imply a vanishing spin Hall effect. We also discuss the situation in which extrinsic spin orbit from impurities is present and the bulk spin Hall conductivity can be different from zero.Comment: Accepted versio

Theory of scanning gate microscopy

A systematic theory of the conductance measurements of non-invasive (weak probe) scanning gate microscopy is presented that provides an interpretation of what precisely is being measured. A scattering approach is used to derive explicit expressions for the first and second order conductance changes due to the perturbation by the tip potential in terms of the scattering states of the unperturbed structure. In the case of a quantum point contact, the first order correction dominates at the conductance steps and vanishes on the plateaus where the second order term dominates. Both corrections are non-local for a generic structure. Only in special cases, such as that of a centrally symmetric quantum point contact in the conductance quantization regime, can the second order correction be unambiguously related with the local current density. In the case of an abrupt quantum point contact we are able to obtain analytic expressions for the scattering eigenfunctions and thus evaluate the resulting conductance corrections.Comment: 19 pages, 7 figure

Spin Hall and Edelstein effects in metallic films: from 2D to 3D

A normal metallic film sandwiched between two insulators may have strong spin-orbit coupling near the metal-insulator interfaces, even if spin-orbit coupling is negligible in the bulk of the film. In this paper we study two technologically important and deeply interconnected effects that arise from interfacial spin-orbit coupling in metallic films. The first is the spin Hall effect, whereby a charge current in the plane of the film is partially converted into an orthogonal spin current in the same plane. The second is the Edelstein effect, in which a charge current produces an in-plane, transverse spin polarization. At variance with strictly two-dimensional Rashba systems, we find that the spin Hall conductivity has a finite value even if spin-orbit interaction with impurities is neglected and "vertex corrections" are properly taken into account. Even more remarkably, such finite value becomes "universal" in a certain configuration. This is a direct consequence of the spatial dependence of spin-orbit coupling on the third dimension, perpendicular to the film plane. The non-vanishing spin Hall conductivity has a profound influence on the Edelstein effect, which we show to consist of two terms, the first with the standard form valid in a strictly two-dimensional Rashba system, and a second arising from the presence of the third dimension. Whereas the standard term is proportional to the momentum relaxation time, the new one scales with the spin relaxation time. Our results, although derived in a specific model, should be valid rather generally, whenever a spatially dependent Rashba spin-orbit coupling is present and the electron motion is not strictly two-dimensional.Comment: 23 pages, 3 figure

On the weak-coupling limit and complete positivity

We consider two non-interacting systems embedded in a heat bath. If they remain dynamically independent, physical inconsistencies are avoided only if the single-system reduced dynamics is completely positive also beyond the weak-coupling limit.Comment: 11 pages, plain-Te

Spin polarizations and spin Hall currents in a two-dimensional electron gas with magnetic impurities

We consider a two-dimensional electron gas in the presence of Rashba spin-orbit coupling, and study the effects of magnetic s-wave impurities and long-range non-magnetic disorder on the spin-charge dynamics of the system. We focus on voltage induced spin polarizations and their relation to spin Hall currents. Our results are obtained using the quasiclassical Green function technique, and hold in the full range of the disorder parameter $\alpha p_F\tau$.Comment: 5 pages, 2 figures. References added, minor stylistic modification

Positively Correlated miRNA-miRNA Regulatory Networks in Mouse Frontal Cortex During Early Stages of Alcohol Dependence

Although the study of gene regulation via the action of specific microRNAs (miRNAs) has experienced a boom in recent years, the analysis of genome-wide interaction networks among miRNAs and respective targeted mRNAs has lagged behind. MicroRNAs simultaneously target many transcripts and fine-tune the expression of genes through cooperative/combinatorial targeting. Therefore, they have a large regulatory potential that could widely impact development and progression of diseases, as well as contribute unpredicted collateral effects due to their natural, pathophysiological, or treatment-induced modulation. We support the viewpoint that whole mirnome-transcriptome interaction analysis is required to better understand the mechanisms and potential consequences of miRNA regulation and/or deregulation in relevant biological models. In this study, we tested the hypotheses that ethanol consumption induces changes in miRNA-mRNA interaction networks in the mouse frontal cortex and that some of the changes observed in the mouse are equivalent to changes in similar brain regions from human alcoholics. Results: miRNA-mRNA interaction networks responding to ethanol insult were identified by differential expression analysis and weighted gene coexpression network analysis (WGCNA). Important pathways (coexpressed modular networks detected by WGCNA) and hub genes central to the neuronal response to ethanol are highlighted, as well as key miRNAs that regulate these processes and therefore represent potential therapeutic targets for treating alcohol addiction. Importantly, we discovered a conserved signature of changing miRNAs between ethanol-treated mice and human alcoholics, which provides a valuable tool for future biomarker/diagnostic studies in humans. We report positively correlated miRNA-mRNA expression networks that suggest an adaptive, targeted miRNA response due to binge ethanol drinking. Conclusions: This study provides new evidence for the role of miRNA regulation in brain homeostasis and sheds new light on current understanding of the development of alcohol dependence. To our knowledge this is the first report that activated expression of miRNAs correlates with activated expression of mRNAs rather than with mRNA downregulation in an in vivo model. We speculate that early activation of miRNAs designed to limit the effects of alcohol-induced genes may be an essential adaptive response during disease progression.NIAAA 5R01AA012404, 5P20AA017838, 5U01AA013520, P01AA020683, 5T32AA007471-24/25Waggoner Center for Alcohol and Addiction Researc

Dissipative effects in semileptonic B decays

We study the time evolution and decay of the neutral B-meson system using quantum dynamical semigroups. New, nonstandard terms appear in the expression of relevant observables; they can be parametrized in terms of six phenomenological constants. Although very small, these parameters may be detected in the new generation of dedicated B-meson experiments.Comment: 14 pages, plain-Te

Complete positivity and correlated neutral kaons

In relation with experiments on correlated kaons at phi-factories, it is shown that the request of complete positivity is necessary in any physically consistent description of neutral kaons as open quantum systems.Comment: LaTeX, 9 page