A Network Model of Alcoholism and Alcohol Policy

The evolution of alcohol dependence in populations of people on different social networks is studied. Two models are studied. One is the evolution of the states of individuals on hypothesized social structures from a rewired connected caveman model. This model spans a range of social structures (networks) from very ordered to effectively random with small world structures in between. The second model is a zip-code-level model which uses data from a recent survey in Delaware. The model is a discrete model using 10 zip codes. The results show that the evolution of alcohol dependence, as governed by the simple rules that we use, depends sensitively on the network structure and a hypothetical treatment regime

Repeated exercise stress impairs volitional but not magnetically evoked electromechanical delay of the knee flexors

The effects of serial episodes of fatigue and recovery on volitional and magnetically evoked neuromuscular performance of the knee flexors were assessed in twenty female soccer players during: (i) an intervention comprising 4x35s maximal static exercise; (ii) a control condition. Volitional peak force (PFV) was impaired progressively (-16 % vs. baseline: 235.3±54.7 to 198.1±38.5 N) by the fatiguing exercise and recovered to within -97 % of baseline values following six-minutes of rest. Evoked peak twitch force (PTFE) was diminished subsequent to the fourth episode of exercise (23.3 %: 21.4±13.8 vs. 16.4±14.6 N) and remained impaired at this level throughout the recovery. Impairment of volitional electromechanical delay performance (EMDV) following the first episode of exercise (25.5 % :55.3±11.9 vs. 69.5±24.5 ms) contrasted with concurrent improvement (10.0 %: 24.5±4.7 vs. 22.1±5.0 ms) in evoked electromechanical delay (EMDE) (p <0.05) and this increased disparity between EMDE and EMDV remained during subsequent periods of intervention and recovery. The fatiguing exercise provoked substantial impairments to volitional strength and EMDV that showed differential patterns of recovery. However, improved EMDE performance might identify a dormant capability for optimal muscle responses during acute stressful exercise and an improved capacity to maintain dynamic joint stabilty during critical episodes of loading

Activity of water in aqueous systems; A frequently neglected property

In this critical review, the significance of the term ‘activity’ is examined in the context of the properties of aqueous solutions. The dependence of the activity of water(ℓ) at ambient pressure and 298.15 K on solute molality is examined for aqueous solutions containing neutral solutes, mixtures of neutral solutes and salts. Addition of a solute to water(ℓ) always lowers its thermodynamic activity. For some solutes the stabilisation of water(ℓ) is less than and for others more than in the case where the thermodynamic properties of the aqueous solution are ideal. In one approach this pattern is accounted for in terms of hydrate formation. Alternatively the pattern is analysed in terms of the dependence of practical osmotic coefficients on the composition of the aqueous solution and then in terms of solute–solute interactions. For salt solutions the dependence of the activity of water on salt molalities is compared with that predicted by the Debye–Hückel limiting law. The analysis is extended to consideration of the activities of water in binary aqueous mixtures. The dependence on mole fraction composition of the activity of water in binary aqueous mixtures is examined. Different experimental methods for determining the activity of water in aqueous solutions are critically reviewed. The role of water activity is noted in a biochemical context, with reference to the quality, stability and safety of food and finally with regard to health science.

What heavy weight buildings in hot climates can tell us about their thermal performance

Concrete, masonry walls and stone finishes are high density materials and have high thermal capacity, they are referred to as heavy-weight construction or thermal mass, which is the main construction type in Lebanon. Although thermal mass construction is usually recommended in hot climates in order to reduce internal temperature fluctuation, its actual thermal behavior in Lebanon is not well documented through direct observation, relying instead on its theoretical performance. This study’s main objective is to characterize the actual thermal performance of such construction, in the context of building occupancy and intermittent A/C usage. The paper starts with a brief introduction of the residential typologies in Lebanon followed by the description of the three thermally monitored apartments, in use or empty, located in one same neighborhood of Beirut, Lebanon. The monitoring was undertaken during summer 2015 using hourly data loggers. The analysis of the recorded data provides a clear and empirical understanding on: 1. how heavy weight buildings interact within the hot and humid climate of Beirut; 2. how the effect of regulating the internal thermal fluctuation is shown; and 3. what are the most influential factors that would further enhance thermal performance of thermal mass construction

A review of minimum U-values for Lebanon and the associated effect of Internal gains

Since 2005 various publications have proposed different U-values to be used in Lebanon to reduce the buildings’ energy demand, creating confusion and a lack of specific and authoritative recommendation. Moreover, the various thermal performance guidelines are not easily comparable due to unexplained basic assumptions and guidance on the calculation of internal gains. This study has two interrelated objectives: a) test the most appropriate U-values for the climate of Beirut, b) study the consequence of increased internal gains have on the cooling energy load in low U-value construction. The paper does dynamic thermal simulation of the various U-values from local and international sources. The analysis allows the comparison and ranking of these various U-values based on the overall yearly energy demand for cooling. This is followed by a sensitivity study where a range of increased internal heat gains are inputted onto a low and a high U-value model to demonstrate that an increase in internal gains results in both models having the same cooling loads. Low U-values under this scenario due not result in a lower annual energy load. The study concludes that, although finding the appropriate U-value for hot climates seems uncontroversial, the effect of internal gains must be taken into consideration. Hence the importance of having consistent and harmonized national and regional benchmark values for U-values and internal gains

Vulnerable adults in the privately rented sector in England: a snapshot of current practice issues

In the UK, in common with many developed countries, there is a crisis in the provision of adequate, affordable and quality housing. This paper discusses how an unprecedented rise in the privately rented housing sector has impacted on housing security for vulnerable adults and the challenges for social work emerging from this situation (The core definition of ‘vulnerable adult’ from the 1997 Consultation ‘Who Decides?’ issued by the Lord Chancellor’s Department, is a person: ‘Who is or may be in need of community care services by reason of disability, age or illness; and is or may be unable to take care of unable to protect him or herself against significant harm or exploitation’. This definition of an adult covers all people over 18 years of age.). We report on a scoping review of the relevant literature and a subsequent online survey of practitioner’s views on the challenges and possible solutions to this issue. Together these provide a snapshot of practice issues and concerns which can be used to promote further debate and help shape recommendations

Knee joint neuromuscular activation performance during muscle damage and superimposed fatigue

This study examined the concurrent effects of exercise-induced muscle damage and superimposed acute fatigue on the neuromuscular activation performance of the knee flexors of nine males (age: 26.7 ± 6.1yrs; height 1.81 ± 0.05m; body mass 81.2 ± 11.7kg [mean ± SD]). Measures were obtained during three experimental conditions: (i) FAT-EEVID, involving acute fatiguing exercise performed on each assessment occasion plus a single episode of eccentric exercise performed on the first occasion and after the fatigue trial; (ii) FAT, involving the fatiguing exercise only and; (iii) CON consisting of no exercise. Assessments were performed prior to (pre) and at lh, 24h, 48h, 72h, and 168h relative to the eccentric exercise. Repeated-measures ANOVAs showed that muscle damage within the FAT-EEVID condition elicited reductions of up to 38%, 24%) and 65%> in volitional peak force, electromechanical delay and rate of force development compared to baseline and controls, respectively (F[io, 80] = 2.3 to 4.6; p to 30.7%>) following acute fatigue (Fp; i6] = 4.3 to 9.1; p ; Fp, iq = 3.9; p <0.05). The safeguarding of evoked muscle activation capability despite compromised volitional performance might reveal aspects of capabilities for emergency and protective responses during episodes of fatigue and antecedent muscle damaging exercise